Infusion set with a massage-hub

• US 9,084,848 B2
• Filed: 11/13/2008
• Issued: 07/21/2015
• Est. Priority Date: 05/15/2006
• Status: Expired due to Fees

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Schiltges, Gilbert, Haeberli, Michael, Kalt, Lucas
• Primary Examiner(s): Bosques, Edelmira
• Application Number:
  US12/270,540
• Publication Number:
  US 20090234272A1
• Time in Patent Office: 2,441 Days
• Field of Search: 604/20, 60428801-28803, 604/469, 604/21, 604/22
• US Class Current: 1/1
• CPC Class Codes: A61H 2201/0207 heated
• CPC Class Codes: A61H 2201/0228 heated by an electric resistance element
• CPC Class Codes: A61H 2201/10 with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
• CPC Class Codes: A61H 23/02 with electric or magnetic drive
• CPC Class Codes: A61H 23/0245 with ultrasonic transducers, e.g. piezoelectric
• CPC Class Codes: A61M 2005/1581 Right-angle needle-type devices
• CPC Class Codes: A61M 2025/0266 using pads, patches, tapes or the like
• CPC Class Codes: A61M 2205/058 with ultrasound therapy
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/158 Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
• CPC Class Codes: A61M 5/44 having means for cooling or heating the devices or media
• CPC Class Codes: A61N 1/0492 Patch electrodes A61N1/0412, A61N1/0428 take precedence
• CPC Class Codes: A61N 1/306 Arrangements where at least part of the apparatus is introduced into the body
• CPC Class Codes: A61N 1/327 for enhancing the absorption properties of tissue, e.g. by electroporation
• CPC Class Codes: A61N 2005/0659 infrared

Abstract

A device and method for stimulating tissue to improve the resorption kinetics of an active substance. The device and method can include an infusion set having a main body, a cannula, and a base plate through which the cannula projects so that the cannula can puncture into a tissue of an animal to deliver the active substance.

Claims

1. An infusion set for placement on a skin surface for delivering an active substance to the body of an animal and for massaging the skin surface around a puncture site to accelerate resorption of an active substance, the infusion set comprising:

a main body;

a cannula supported on the main body and protruding into a coupling area of the main body; and

a base plate through which the cannula projects such that the cannula can puncture into a tissue of the animal to deliver the active substance, wherein the base plate includes a device spaced from the cannula such that the cannula has no contact with the device which stimulates the skin surface around the puncture site of the cannula for an extended period of time of more than one minute after puncturing the tissue with the cannula to increase the flow of blood and the resorption of an administered active substance, wherein the base plate vibrates, oscillates, emits thermal radiation, or combinations thereof, to improve blood flow; and

wherein an underside of the base plate comprises apertures designed as sectors of a circle, and the underside of the base plate has projections that are directed through the apertures toward the skin surface to be stimulated, the sectors of the circle surrounding and spaced from the cannula and the sectors of the circle having a spacing present between the apertures in a circumferential direction, for the massaging of the skin surface around the puncture site to accelerate the resorption of the active substance.

2. The infusion set of claim 1, wherein the device is removably attached to the main body.

3. The infusion set of claim 1, wherein the device is designed to be connected to and detached from the main body via an adhesive layer, hook and loop fasteners, bayonet catches, cooperating locking elements or complementary locking elements.

4. The infusion set of claim 1, wherein the base plate can be mounted substantially with a cross-sectional form fit onto the main body such that it bears on the main body.

5. The infusion set of claim 1, further comprising a self-adhesive layer on an upper face of the base plate.

6. The infusion set of claim 1, wherein the device is disc-shaped, and can be pushed or plugged onto the main body.

7. The infusion set of claim 1, wherein the device further comprises an energy supply in the form of one of an accumulator and/or energy-storing cells.

8. The infusion set of claim 1, further comprising a lead coupled to the main body or the device that is configured to carry at least one of electrical energy and control signals.

9. The infusion set of claim 8, wherein the lead is one of connected to an infusion set tubing or formed in one piece with the tubing.

10. The infusion set of claim 1, wherein the projections radiate heat, transmit heat, release chemical substances, or emit electrical stimulating currents.

11. The infusion set of claim 1, wherein the device has the shape of a flat disc.

12. The infusion set of claim 1, wherein a bottom surface of the projections lies flush with the underside of the base plate.

13. The infusion set of claim 1, wherein the base plate comprises the underside for positioning on the body of the animal, the underside having an adhesive layer coupled thereto for securing the infusion set to the body of the animal.

14. The infusion set of claim 1, wherein the device is configured to stimulate the tissue around the puncture site of the cannula up to thirty minutes after puncturing the tissue with the cannula.

15. The infusion set of claim 1 wherein the cannula projects through a generally central cutout of the device defining a space having an outer perimeter, the space located between the cannula and the device, and the infusion set is configured to deliver stimulation outside of the space provided by the cutout.

16. A method of placing an infusion set on a skin surface for delivering an active substance to the body of an animal and for massaging the skin surface around a puncture site to accelerate resorption of an active substance, the method comprising:

providing the infusion set comprising;

a main body;

a cannula supported on the main body and protruding into a coupling area of the main body; and

a base plate through which the cannula projects such that the cannula can puncture into a tissue of the animal to deliver the active substance, wherein the base plate includes a device spaced from the cannula such that the cannula has no contact with the device which stimulates the skin surface around the puncture site of the cannula for an extended period of time of more than one minute after puncturing the tissue with the cannula to increase the flow of blood and the resorption of an administered active substance, wherein the base plate vibrates, oscillates, emits thermal radiation, or combinations thereof, to improve blood flow; and

wherein an underside of the base plate comprises apertures designed as sectors of a circle, and the underside of the base plate has projections that are directed through the apertures toward the skin surface to be stimulated, the sectors of the circle surrounding and spaced from the cannula and the sectors of the circle having a spacing present between the apertures in a circumferential direction, for the massaging of the skin surface around the puncture site to accelerate the resorption of the active substance; and

placing the infusion set on the skin surface, stimulating the skin surface, and infusing the active substance into the body of the animal.

17. The method of claim 16, wherein the device is removably attached to the main body.

18. The method of claim 17, wherein the device is designed to be connected to and detached from the main body via an adhesive layer, hook and loop fasteners, bayonet catches, cooperating locking elements or complementary locking elements.

19. The method of claim 16, wherein the base plate can be mounted substantially with a cross-sectional form fit onto the main body such that it bears on the main body.

20. The method of claim 16, further comprising a self-adhesive layer on an upper face of the base plate.

21. The method of claim 16, wherein the device is disc-shaped, and can be pushed or plugged onto a main body.

22. The method of claim 16, wherein the device further comprises an energy supply comprising at least one of an accumulator or energy-storing cells.

23. The method of claim 16, wherein the infusion set further comprises a lead configured for carrying at least one of electrical energy and control signals.

24. The method of claim 23, wherein the lead is one of connected to an infusion set tubing or formed in one piece with the tubing.

25. The method of claim 16, wherein the projections radiate heat, transmit heat, release chemical substances, or emit electrical stimulating currents.

26. The method of claim 16, wherein the device has the shape of a flat disc.

27. An infusion set for placement on a skin surface for delivering an active substance to the body of an animal and for massaging the skin surface around a puncture site to accelerate resorption of an active substance, the infusion set comprising:

a main body;

a cannula supported on the main body and protruding into a coupling area of the main body; and

a base plate through which the cannula projects such that the cannula can puncture into a tissue of the animal to deliver the active substance, wherein the base plate includes a device spaced from the cannula such that the cannula has no contact with the device which stimulates the skin surface around the puncture site of the cannula for an extended period of time of more than one minute after puncturing the tissue with the cannula to increase the flow of blood and the resorption of an administered active substance, wherein the base plate vibrates; and

wherein an underside of the base plate comprises apertures designed as sectors of a circle, and the underside of the base plate has projections that are directed through the apertures toward the skin surface to be stimulated, the sectors of the circle surrounding and spaced from the cannula and the sectors of the circle having a spacing present between the apertures in a circumferential direction, for the massaging of the skin surface around the puncture site to accelerate the resorption of the active substance.

28. The infusion set of claim 27, wherein the device is configured to stimulate the tissue around the puncture site of the cannula for up to thirty minutes after puncturing the tissue with the cannula.

29. An infusion set for placement on a skin surface for delivering an active substance to the body of an animal and for massaging the skin surface around a puncture site to accelerate resorption of an active substance, the infusion set comprising:

a main body;

a cannula supported on the main body and protruding into a coupling area of the main body;

a base plate through which the cannula projects such that the cannula can puncture into a tissue of the animal to deliver the active substance, wherein the base plate includes a device spaced from the cannula such that the cannula has no contact with the device which stimulates the skin surface around the puncture site of the cannula for an extended period of time of more than one minute after puncturing the tissue with the cannula to increase the flow of blood and the resorption of an administered active substance, wherein the base plate vibrates, oscillates, emits thermal radiation, or combinations thereof, to improve blood flow; and

a reservoir coupled to the infusion set, wherein the reservoir contains an amount of the active substance effective for increasing the flow of blood and being resorbed; and

wherein an underside of the base plate comprises apertures designed as sectors of a circle, and the underside of the base plate has projections that are directed through the apertures toward the skin surface to be stimulated, the sectors of the circle surrounding and spaced from the cannula and the sectors of the circle having a spacing present between the apertures in a circumferential direction, for the massaging of the skin surface around the puncture site to accelerate the resorption of the active substance.