Flow balancing and synchronization system

• US 9,084,855 B2
• Filed: 02/03/2012
• Issued: 07/21/2015
• Est. Priority Date: 10/15/2003
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Ware, Lee C., Boehnlein, Arnold F.
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US13/365,654
• Publication Number:
  US 20120132574A1
• Time in Patent Office: 1,264 Days
• Field of Search: 604 401- 616, 604/151, 604 65- 67, 604/131
• US Class Current: 1/1
• CPC Class Codes: A61M 1/3434 with pre-dilution and post-dilution
• CPC Class Codes: A61M 1/3437 downstream of the filter, e.g. post-dilution with filtrate
• CPC Class Codes: A61M 1/3441 Substitution rate control as a function of the ultrafiltration rate
• CPC Class Codes: A61M 1/3451 the difference in weight between both ultra-filtrate and substitution reservoir being used as control signal
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

A renal failure therapy system includes a blood circuit with a blood pump and a drug delivery pump. A control unit is operable with the blood pump and the drug delivery pump to control the drug delivery pump based upon the status of the blood pump.

Claims

1. A blood filtration system comprising:

a blood filtration machine including;

(i) a blood filter;

(ii) a blood filtration machine controller housed within the blood filtration machine; and

(iii) a blood pump housed within the blood filtration machine;

a blood circuit in fluid communication with the blood filter and the blood pump; and

a drug delivery device including a substitution solution pump and a substitution solution pump controller, the drug delivery device housed external to the blood filtration machine, wherein the substitution solution pump is positioned and arranged to pump at least one medical fluid from a substitution solution fluid source into the blood circuit, wherein

the blood filtration machine controller is operable with the substitution solution pump controller to cause the substitution solution pump controller to automatically prevent the substitution solution pump from operating if the blood filtration machine controller determines that the blood pump is not running.

2. The blood filtration system of claim 1, wherein, the blood filtration machine controller is further operable with the substitution solution pump controller to cause the substitution solution pump controller to enable the substitution solution pump to operate when the blood filtration machine controller determines that the blood pump is operating.

3. The blood filtration system of claim 1, which further includes a blood flow detector that sends a blood flow signal to the blood filtration machine controller, the blood flow signal indicative of whether or not the blood pump is running.

4. The blood filtration system of claim 1, wherein the control unit is further configured to adjust a delivery flow rate of the substitution solution pump controller based upon the blood flow signal.

5. A blood filtration system comprising:

a blood filtration machine including a blood filter, a blood filtration machine controller, and a blood pump, wherein the blood filter, the blood filtration machine controller and the blood pump are housed within the blood filtration machine;

a blood circuit in fluid communication with the blood filter and the blood pump;

a plurality of substitution fluid pumps external to the blood filtration machine, wherein the plurality of external substitution fluid pumps are each positioned and arranged to pump a substitution fluid into the blood circuit; and

a plurality of substitution fluid pump controllers, each substitution fluid pump controller associated with one of the respective substitution fluid pumps, wherein

the blood filtration machine controller is operable to;

(i) determine if the blood pump is running, and (ii) if the blood pump is running, cause at least one of the plurality of substitution fluid pump controllers to enable the associated external substitution fluid pump(s) to be operated.

6. The blood filtration system of claim 5, wherein each of the plurality of external substitution fluid pumps from a different substitution fluid source into the blood circuit.

7. The blood filtration system of claim 5, which includes at least one substitution fluid source, and wherein each of the plurality of external substitution fluid pumps is positioned and arranged to pump the same fluid from the at least one fluid source into the blood circuit.

8. The blood filtration system of claim 5, which further includes a blood flow detector that sends a blood flow signal to the blood filtration machine controller, the signal indicative of whether or not the blood pump is running.

9. A blood filtration system comprising:

a blood filtration machine including a blood filter, a blood filtration machine controller and a blood pump, wherein the blood filter, the blood filtration machine controller and the blood pump are housed within the blood filtration machine;

a blood circuit in fluid communication with the blood filter and the blood pump; and

a drug delivery device including a substitution solution pump and a substitution solution pump controller, the drug delivery device housed external to the blood filtration machine, wherein the substitution solution pump is positioned and arranged to pump at least one medical fluid from a substitution solution fluid source into the blood circuit, wherein

the blood filtration machine controller is operable with the substitution solution pump controller to cause the substitution solution pump controller to only allow the substitution solution pump to operate when the blood filtration machine controller determines that the blood pump is operating.

10. A blood filtration system comprising:

a blood filtration machine including a blood filter, a blood filtration machine controller, and a blood pump configured to pump blood from a patient at a blood flowrate, wherein the blood filter, the blood filtration machine controller and the blood pump are housed within the blood filtration machine;

a blood circuit in fluid communication with the blood filter and the blood pump; and

a drug delivery device including a substitution solution pump and a substitution solution pump controller, the drug delivery device housed external to the blood filtration machine, wherein the substitution solution pump is positioned and arranged to pump at least one substitution solution from the drug delivery device into the blood circuit at a substitution solution flowrate,

wherein,

the blood filtration machine controller is operable with the substitution solution pump controller to cause the substitution solution pump controller to automatically adjust the substitution solution flowrate based upon the blood flowrate.

11. The blood filtration system of claim 10, wherein the substitution solution pump controller is configured to adjust the substitution solution flowrate based upon a chemical property of the substitution solution.

12. The blood filtration system of claim 10, which includes an electrolyte sensor in the blood circuit and in communication with the blood filtration machine controller, and wherein the substitution solution pump controller is configured to operate with the blood filtration machine controller to adjust the substitution solution flowrate based upon electrolyte levels provided by the blood filtration machine controller from the electrolyte sensor.

13. A blood filtration system comprising:

a blood filtration machine including a blood filter, a blood filtration machine controller, and a blood pump configured to pump blood from a patient at a blood flowrate, wherein the blood filter, the blood filtration machine controller and the blood pump are housed within the blood filtration machine;

a blood circuit in fluid communication with the blood filter and the blood pump;

a plurality of substitution fluid pumps external to the blood filtration machine, wherein each of the plurality of external substitution fluid pumps is configured to pump a substitution fluid into the blood circuit at a substitution fluid flowrate; and

a plurality of substitution fluid pump controllers, each substitution fluid pump controller associated with one of the respective substitution fluid pumps, wherein

the blood filtration machine controller is operable with each of the plurality of substitution fluid pump controllers to;

(i) cause the blood filtration machine controller to determine the blood flowrate, and (ii) cause at least one of the plurality of substitution fluid pump controllers to adjust the substitution fluid flowrate of at least one of the substitution fluid pumps based upon the blood flowrate.

14. The blood filtration system of claim 13, wherein the substitution fluid is an intravenous fluid.

15. The blood filtration system of claim 13, wherein each of the plurality of substitution fluid pumps from a different source into the blood circuit.

16. The blood filtration system of claim 13, wherein each of the plurality of substitution fluid pumps a same fluid from different fluid sources into the blood circuit.

17. The blood filtration system of claim 13, wherein the plurality of external substitution fluid pumps are infusion pumps.

18. The blood filtration system of claim 13, which also includes a blood flow detector that indicates a blood flow signal to the blood filtration machine controller based upon whether the blood pump is running.