Neuromodulation system and method for reducing energy requirements using feedback

• US 9,084,900 B2
• Filed: 06/28/2013
• Issued: 07/21/2015
• Est. Priority Date: 06/29/2012
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Hershey, Bradley L., Bradley, Kerry
• Primary Examiner(s): Wieland, Robert N
• Application Number:
  US13/930,176
• Publication Number:
  US 20140005744A1
• Time in Patent Office: 753 Days
• Field of Search: 607/46
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0209 adapted for power saving
• CPC Class Codes: A61B 5/4833 Assessment of subject's compliance to treatment
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36128 Control systems
• CPC Class Codes: A61N 1/36132 using patient feedback
• CPC Class Codes: A61N 1/3614 based on impedance measurement
• CPC Class Codes: A61N 1/36171 Frequency
• CPC Class Codes: A61N 1/37211 Means for communicating with stimulators

Abstract

An electrical neuromodulation system and method of meeting a therapeutic goal for a patient using a neuromodulation device. A modulation parameter value is varied by a step size. The neurostimulation device instructs the neuromodulation device to deliver electrical energy to at least one electrode in accordance with the varied modulation parameter value. A therapeutic feedback indicator is compared to a threshold in response to the delivery of the electrical energy. Whether the therapeutic goal has been met is determined based on the comparison, and the previous steps are repeated to determine the modulation parameter value at the resolution of the step size that minimizes energy consumption of the neuromodulation device required to meet the therapeutic goal when delivering the electrical energy to the electrode(s) in accordance with the varied modulation parameter value.

Claims

1. An electrical neuromodulation system, comprising:

a neuromodulation device capable of delivering electrical energy to at least one electrode in accordance with a modulation parameter value;

memory configured for storing a threshold indicative of a therapeutic goal; and

control/processing circuitry configured tier automatically (a) varying the modulation parameter value by a step size, (b) instructing the neuromodulation device to deliver the electrical energy to the at least one electrode in accordance with the varied modulation parameter value, (c) comparing a therapeutic feedback indicator to the stored threshold in response to the delivery of the electrical energy, (d) determining whether the therapeutic goal has been met based on the comparison, and (e) repeating steps (a)-(d) to determine the modulation parameter value at the resolution of the step size that minimizes energy consumption of the neuromodulation device required to meet the therapeutic goal when delivering the electrical energy to the at least one electrode in accordance with the varied modulation parameter value.

2. The electrical neuromodulation system of claim 1, wherein the controller/processor is configured for incrementally varying the modulation parameter value at step (a) to increase the energy consumption of the neuromodulation device, and if the therapeutic goal is initially determined to not be met at step (d), repeating steps (a)-(d) until the therapeutic goal has been determined to be met at step (d), such that the modulation parameter value that minimizes energy consumption of the neuromodulation device required to meet the therapeutic goal is determined to be the last modulation parameter value.

3. The electrical neuromodulation system of claim 1, wherein the controller/processor is configured for incrementally varying the modulation parameter value at step (a) to decrease the energy consumption of the neuromodulation device, and if the therapeutic goal is initially determined to he met at step (d), repeating steps (a)-(d) until the therapeutic goal has been determined to not be met at step (d), such that the modulation parameter value that minimizes energy consumption of the neuromodulation device required to meet the therapeutic goal is determined to be the previous modulation parameter value.

4. The electrical neuromodulation system of claim 1, wherein the electrical energy is pulsed electrical energy.

5. The electrical neuromodulation system of claim 4, wherein the modulation parameter is a pulse rate.

6. The electrical neuromodulation system of claim 4, wherein the modulation parameter is a pulse width.

7. The electrical neuromodulation system of claim 1, wherein the modulation parameter is a duty cycle.

8. The electrical neuromodulation system of claim 1, wherein the modulation parameter is an amplitude.

9. The electrical neuromodulation system of claim 1, wherein the modulation parameter is an electrode combination.

10. The electrical neuromodulation system of claim 1, wherein therapeutic feedback indicator is conscious feedback from the patient.

11. The electrical neuromodulation system of claim 1, further comprising at least one sensor configured for sensing the therapeutic feedback indicator.

12. The electrical neuromodulation system of claim 11, wherein the therapeutic indicator is one of a body activity, body temperature, blood flow, electrocardiogram and derived autonomic tone metrics thereof, electrocortigram, electroencephalogram, tissue or transcutaneous oxygen tension, glucose concentration, electrode impedance, compound action potentials, intra- or extra-cellular potential or electrical current, and chemical species concentration.

13. The electrical neuromodulation systemclaim 1, wherein the the therapeutic goal is the alleviation of chronic pain.

14. The electrical neuromodulation system of claim 1, wherein the neuromodulation device is configured for conveying the electrical energy at a frequency in the range of 1 KHz-50 KHz.

15. The electrical neuromodulation system of claim 1, wherein the memory and control/processing circuitry are contained in the neuromodulation device.

16. The electrical neuromodulation system of claim 1, wherein the memory and control/processing circuitry are contained in an external control device.

17. The electrical neuromodulation system of claim 1, further comprising a battery configured for storing power used to generate the electrical energy.