Ultrasound guided tissue ablation

• US 9,089,340 B2
• Filed: 12/21/2011
• Issued: 07/28/2015
• Est. Priority Date: 12/30/2010
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Hastings, Roger, Koblish, Josef V., Pikus, Michael J., Richardson, Leonard B., Edmunds, Kevin, Teo, Tat-Jin
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): CAREY, MICHAEL JAMES
• Application Number:
  US13/332,570
• Publication Number:
  US 20120172871A1
• Time in Patent Office: 1,315 Days
• Field of Search: 606/41, 606/34
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00011 with fluids
• CPC Class Codes: A61B 2018/00357 Endocardium
• CPC Class Codes: A61B 2018/00404 Blood vessels other than those in or around the heart
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00511 Kidney
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2218/002 Irrigation
• CPC Class Codes: A61B 8/0891 for diagnosis of blood vessels
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/14 Echo-tomography
• CPC Class Codes: A61B 8/445 Details of catheter construction

Abstract

An imaging assembly comprises a catheter having a distal end and a proximal end, an ablation tip at the distal end of the catheter, and an imaging device disposed within the ablation tip. The catheter defines a catheter lumen that extends from the proximal end to the distal end. The catheter is configured and arranged for insertion into a body lumen such as a blood vessel or heart chamber. The ablation tip has a wall that defines a lumen in communication with the lumen of the catheter. The imaging device is disposed within the lumen of the ablation tip, and is configured to transmit pulsed acoustic waves for generating images of body tissue at a target ablation site within the body.

Claims

1. An ultrasound imaging assembly for an ablation system, the imaging assembly comprising:

a catheter having a proximal end and a distal end, the catheter defining a catheter lumen extending from the proximal end to the distal end, the catheter configured and arranged for insertion into a bodily lumen;

an ablation tip at the distal end of the catheter, the ablation tip having a wall that defines a lumen, the wall including a plurality of openings, the lumen of the ablation tip in communication with the lumen of the catheter, the wall formed by metal and configured to deliver ablation energy to tissue; and

an imaging device disposed at least in part within the lumen of the ablation tip, the imaging device comprising a plurality of ultrasonic transducers disposed within the lumen of the ablation tip and positioned to direct acoustic signals through the plurality of openings, respectively, the imaging device further comprising a drive motor within the lumen of the ablation tip.

2. The imaging assembly of claim 1, wherein each ultrasonic transducer is configured and arranged for transducing applied electrical signals to the acoustic signals and for transducing received echo signals to electrical signals.

3. The imaging assembly of claim 1, wherein the drive motor is configured to receive electrical current that drives the drive motor to rotate.

4. The imaging assembly of claim 1, wherein the plurality of ultrasonic transducers comprises a first transducer and a second transducer, the first ultrasonic transducer is configured for imaging tissue located distally of the distal end of the ablation tip, and wherein the second ultrasonic transducer is configured for imaging tissue located adjacent to a circumference of the ablation tip.

5. The imaging assembly of claim 1, wherein the motor is coaxially aligned with each of the ultrasonic transducers.

6. The imaging assembly of claim 1, wherein the drive motor includes a stator and a rotor.

7. The imaging assembly of claim 6, wherein the stator comprises a three-phase winding for receiving three-phase current.

8. The imaging assembly of claim 6, wherein at least one of the ultrasonic transducers is fixed.

9. The imaging assembly of claim 8, further comprising a reflective surface that is rotatably coupled to the rotor of the motor, and wherein the acoustic signals produced by the at least one fixed ultrasonic transducer are reflected by the reflective surface through the openings.

10. The imaging assembly of claim 9, wherein the reflective surface is planar.

11. The imaging assembly of claim 9, wherein the reflective surface is non-planar.

12. The imaging assembly of claim 6, wherein at least one ultrasonic transducer is rotatably coupled to the rotor.

13. The imaging assembly of claim 12, wherein the imaging device includes a transformer configured for electrically coupling the at least one ultrasonic transducer to an electrical lead within the lumen of the catheter.

14. The imaging assembly of claim 13, wherein the transformer is further configured for rotatably coupling the at least one ultrasonic transducer to the rotor.

15. The imaging assembly of claim 1, further comprising a sensing device configured for sensing a location of the ablation tip within the bodily lumen.

16. The imaging assembly of claim 1, wherein the plurality of openings comprises a plurality of side openings and at least one front opening.

17. The imaging assembly of claim 1, further comprising:

a user interface; and

a control unit electrically coupled to the imaging device.

18. The imaging assembly of claim 17, wherein the control unit comprises:

a pulse generator electrically coupled to the ultrasonic transducers via at least one transducer conductor, the pulse generator configured for generating electric signals that are applied to each ultrasonic transducer during an imaging scan;

an ablation control unit electrically coupled to the ablation tip;

a motor control unit configured for controlling the motor; and

a processor electrically coupled to the ultrasonic transducers via the at least one transducer conductor.

19. An ultrasound imaging assembly for an ablation system, the imaging assembly comprising:

a catheter having a proximal end and a distal end, the catheter defining a catheter lumen extending from the proximal end to the distal end, the catheter configured and arranged for insertion into a bodily lumen;

an ablation tip at the distal end of the catheter, the ablation tip having a wall defining a lumen in communication with the lumen of the catheter; and

an imaging device disposed at least in part within the lumen of the ablation tip, the imaging device comprising;

a first stationary ultrasonic transducer located within the lumen of the ablation tip, the first stationary ultrasonic transducer configured to generate acoustic pulses and orientated to project the acoustic pulses in a first direction distally of the distal end of the ablation tip for imaging tissue located distally of the distal end of the ablation tip;

a second stationary ultrasonic transducer located within the lumen of the ablation tip, the second stationary ultrasonic transducer coaxially aligned with the first stationary ultrasonic transducer, the second stationary ultrasonic transducer configured to generate acoustic pulses and orientated to project the acoustic pulses in a second direction that is opposite the first direction; and

a drive motor configured for rotating a reflective surface within the lumen of the ablation tip, wherein the reflective surface is configured for reflecting the acoustic pulses generated by the second stationary ultrasonic transducer in a lateral direction with respect to the ablation tip for imaging tissue located adjacent to a circumference of the ablation tip.

20. An ultrasound imaging assembly for an ablation system, the imaging assembly comprising:

a catheter having a distal end and a proximal end, the catheter defining a catheter lumen extending from the proximal end to the distal end, the catheter configured and arranged for insertion into a bodily lumen;

an ablation tip at the distal end of the catheter, the ablation tip having a wall defining a lumen in communication with the lumen of the catheter; and

an imaging device disposed at least in part within the lumen of the ablation tip, the imaging device comprising;

a first ultrasonic transducer configured for imaging tissue located distally of the distal end of the ablation tip;

a second ultrasonic transducer configured for imaging tissue located adjacent to a circumference of the ablation tip; and

a transformer comprising a stator and a rotor, the stator and the rotor inductively coupled to one another, the transformer electrically coupling the first and second ultrasonic transducers to an electrical lead via the inductive coupling between the stator and the rotor, wherein the transformer is configured for rotating the first and second ultrasonic transducers within the lumen of the ablation tip.