Systems and methods for treating dyspnea, including via electrical afferent signal blocking

• US 9,089,700 B2
• Filed: 08/07/2009
• Issued: 07/28/2015
• Est. Priority Date: 08/11/2008
• Status: Active Grant

• Current Assignee: Cibiem, Inc.
• Original Assignee: Cibiem, Inc.
• Inventors: Hlavka, Edwin J., Elliott, Lynn S.
• Primary Examiner(s): PATTON, AMANDA K
• Application Number:
  US12/537,984
• Publication Number:
  US 20100070004A1
• Time in Patent Office: 2,181 Days
• Field of Search: 607/42
• US Class Current: 1/1
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: A61N 1/3601 of respiratory organs

Abstract

Systems and methods for treating a patient with dyspnea are disclosed. A method in accordance with a particular embodiment includes identifying the patient as suffering from dyspnea, and, based at least in part on identifying the patient as suffering from dyspnea, implanting an electrical signal delivery element within the patient in signal communication with an afferent neural pathway of a carotid body chemoreceptor. The method can further include at least reducing dyspneic sensations in the patient by directing an electrical signal from the electrical signal delivery element to the neural pathway to at least partially block afferent signals from the chemoreceptor.

Claims

1. A method for treating a patient comprising directing an electrical signal from an electrical signal delivery device to a carotid body in a human patient to block afferent signals from the carotid body,

further comprising positioning the electrical signal delivery device with respect to the carotid body such that blocking the afferent signals from the carotid body with the electrical signal does not interfere with afferent signals transmitted by baroreceptor neurons in the patient,

wherein the blocking of the afferent signals achieves a therapeutic effect by disabling a function of the carotid body in sensing hypoxia or hypercapnia.

2. The method of claim 1 wherein directing an electrical signal from an electrical signal delivery device to a carotid body comprises directing an electrical signal in bipolar mode.

3. The method of claim 1 further comprising, prior to directing the electrical signal, simulating carotid body inhibition.