Device for measuring at least one parameter of an arterial blood sample

• US 9,091,660 B2
• Filed: 01/12/2010
• Issued: 07/28/2015
• Est. Priority Date: 01/13/2009
• Status: Active Grant

• Current Assignee: Smart Medical Solutions GmbH
• Original Assignee: Smart Medical Solutions GmbH
• Inventors: Koehler, Hans
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Fardanesh, Marjan
• Application Number:
  US13/144,364
• Publication Number:
  US 20110275913A1
• Time in Patent Office: 2,023 Days
• Field of Search: 600310-344
• US Class Current: 1/1
• CPC Class Codes: A61B 5/1427 Multiple blood sampling, e.g. at periodic or pre-established intervals
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14557 specially adapted to extracorporeal circuits
• CPC Class Codes: A61B 5/15003 for venous or arterial blood
• CPC Class Codes: A61B 5/150389 Hollow piercing elements, e.g. canulas, needles, for piercing the skin
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/15074 Needle sets comprising wings, e.g. butterfly type, for ease of handling
• CPC Class Codes: A61B 5/150992 Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves tubing connectors and couplings A61M39/00
• CPC Class Codes: A61B 5/153 Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
• CPC Class Codes: G01N 2021/7763 Sample through flow
• CPC Class Codes: G01N 21/77 by observing the effect on a chemical indicator
• CPC Class Codes: G01N 21/7703 using reagent-clad optical fibres or optical waveguides using measurement of total internal reflection or attenuated total reflection G01N21/552; optical fibres or waveguides per se G02B
• CPC Class Codes: G01N 21/80 Indicating pH value

Abstract

The invention relates to a device for measuring at least one parameter of an arterial blood sample, including a flow sensor having standardized connecting elements which are connected to the inlet and the outlet side of a measuring cell of the flow sensor, the measuring cell having at least one optochemical sensor element which can be brought in contact with the blood sample. A connector is removably placed on the flow sensor and includes at least one light source for exciting the optochemical sensor element and at least one photodetector for receiving the measurement radiation of the optochemical sensor element. An electronic module has an electric connecting line to the connector and contacts the at least one light source and the at least one photodetector, the flow sensor being connectible to the standardized connection of an arterial catheter via the connecting element on the inlet side and to the standardized connection of an arterial infusion set via the connection on the outlet side.

Claims

1. A device for measuring at least one parameter of an arterial blood sample, the device comprising:

a disposable flow-through sensor including a measuring cell configured to receive the arterial blood sample;

wherein the measuring cell is detachably connected between an inlet standardized connecting element and an outlet standardized connecting element of the flow-through sensor;

at least one optochemical sensor element within the measuring cell that contacts the arterial blood sample received by the measuring cell;

a reusable connector, which can be detachably plugged externally onto the flow-through sensor including the measuring cell containing the at least one optochemical sensor element, the connector including at least one light source for excitation of the optochemical sensor element and at least one photodetector for receiving the measurement radiation of the optochemical sensor element, wherein the at least one light source and the at least one photodetector of the connector do not come in contact with the received arterial blood sample when the connector is plugged onto the flow-through sensor,

an electronic module with an electrical connecting line to the connector, the module in contact with the at least one light source and the at least one photodetector,

the inlet standardized connecting element coupled to an inlet side of the measuring cell for removable connection to a standardized fitting of an arterial catheter; and

the outlet standardized connecting element coupled to an outlet side of the measuring cell for removable connection to a standardized fitting of an arterial infusion set.

2. The device according to claim 1, wherein the electronic module is provided with an electrical connecting line or with a wireless link to an evaluation and display unit.

3. The device according to claim 1, wherein the electronic module is integrated in an evaluation and display unit.

4. The device according to claim 1, wherein a piece of flexible tubing is provided between either the connecting element on the inlet side or the connecting element on the outlet side of the flow-through sensor and the measuring cell to relieve the arterial catheter from mechanical load.

5. The device according to claim 1, wherein the connector has a clamp which grips the flow-through sensor in a mechanically stable way.

6. The device according to claim 1, further comprising an optical measuring element in the measuring cell of the flow-through sensor, which on contact with the blood sample emits a starting signal for activating parameter measurement.

7. The device according to claim 6, wherein the optical measuring element is configured to generate a warning signal when the blood sample enters the flow-through sensor by mistake.

8. The device according to claim 1, further comprising a manually actuated aspiration piston of the arterial infusion set configured to aspirate the blood sample into the measuring cell of the flow-through sensor.

9. The device according to claim 1, further comprising an automatically actuated piston or peristaltic pump configured to aspirate the blood sample into the measuring cell of the flow-through sensor.

10. The device according to claim 1, wherein the measuring cell of the flow-through sensor additionally is provided with a sensor for temperature measurement.

11. The device according to claim 10, wherein the sensor for temperature measurement is configured to detect a rise in temperature based on the flow of the blood sample.

12. The device according to claim 11, wherein an automated system is configured to start measurement of the at least one parameter upon the sensor for temperature measurement detecting the rise in temperature.

13. The device according to claim 1, wherein the measuring cell of the flow-through sensor is provided with at least one sensor for measuring a parameter selected from the group consisting of O₂, CO₂, pH, sodium, potassium, glucose, lactate and temperature.

14. The device according to claim 1, wherein the connector further comprises a clamp configured to grip the flow-through sensor to align the at least one light source and the at least one photodetector of the connector with the optochemical sensor element within the measuring cell.