Neural interface device and insertion tools

• US 9,095,267 B2
• Filed: 12/21/2012
• Issued: 08/04/2015
• Est. Priority Date: 12/22/2011
• Status: Active Grant

• Current Assignee: Modular Bionics, Inc.
• Original Assignee: Modular Bionics, Inc.
• Inventors: Halpern, Ian Loren, Merlo, Mark William
• Primary Examiner(s): Cohen, Lee S
• Application Number:
  US13/725,732
• Publication Number:
  US 20130172717A1
• Time in Patent Office: 956 Days
• Field of Search: 600/377, 600/378, 600/544, 607/116
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/685 Microneedles
• CPC Class Codes: A61N 1/0502 Skin piercing electrodes
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor

Abstract

An implanted neural micro interface device is provided. The device comprises microfilaments of various materials and forms embedded within a body. The microfilaments form interaction sites with surrounding neural tissue at their exit points from the implantable body. The body and filaments are configurable in a multitude of positions to provide increased engagement of a given neural tissue section as well as interaction and closed loop feedback between the microfilament sites. Such configurations allow for a range of recording, stimulating, and treatment modalities for the device within research and clinical settings.

Claims

1. A neural microarray, comprising:

a base member configured to be sufficiently flexible to bend around the curvature of neural tissue;

a plurality of elongate shafts extending from the base member, the elongate shafts each having a sidewall, a channel therethrough; and

a plurality of sites in communication with the channel and spaced apart along the sidewall; and

a plurality of microfilaments housed within the channel of the plurality of elongate shafts and extending proximally from at least the base member and at least one of the microfilaments each extending distally out each of the plurality of sites, wherein each of the microfilaments are configured to stimulate tissue or record a tissue parameter,

wherein the base member has a major axis that is transverse to the major axis of the plurality of the elongate shafts, wherein a thickness dimension of the base member parallel to the major axis of the plurality of the elongate shafts is no more than about 10 times the average diameter of the plurality of microfilaments.

2. The microarray of claim 1, further comprising at least one site disposed on a surface of the base member, at least one of the microfilaments extending distally out of the site.

3. The microarray of claim 1, wherein the base member comprises a first portion, a second portion, and a hinged portion separating the first portion and the second portion, the first portion and the second portion comprising at least one of the elongate shafts thereon.

4. The microarray of claim 1, wherein the sites are configured such that the microfilaments extending distally out of each of the plurality of sites are configured to be movable in at least 6 degrees of freedom when inserted in or proximate neural tissue.

5. The microarray of claim 1, wherein the sites are spaced axially apart along longitudinal axes of the shafts.

6. The microarray of claim 1, wherein the shafts comprise a helical shape.

7. The microarray of claim 1, wherein the shafts comprise a proximal non-linear portion and a distal linear portion.

8. The microarray of claim 7, wherein the proximal non-linear portion is curved.

9. The microarray of claim 1, further comprising a power source operably connected to the microfilaments.

10. The microarray of claim 1, further comprising an amplifier operably connected to the microfilaments.

11. The neural microarray of claim 1, wherein the microarray is a continuous body.

12. The neural microarray of claim 11, wherein the continuous body is integrally formed of a single material.

13. The neural microarray of claim 1, wherein at least one of the microfilaments has a portion that is substantially orthogonal to the major axis of the base member.

14. A microarray system comprising the microarray of claim 1, and a power source wirelessly connectable to the microfilaments.