Analyte concentration detection devices and methods
First Claim
1. A device for conducting an assay to determine the concentration of an analyte in a sample of bodily fluid, the device comprising:
- a microneedle configured to collect the sample and comprising a lumen therethrough;
an elongate sample collection channel transverse to the lumen of the microneedle, wherein the sample collection channel comprises a proximal end and a distal end, and wherein the proximal end is in communication with the lumen of the microneedle;
an assay pad comprising a reagent that produces a reaction when exposed to the analyte, wherein the assay pad is in communication with the sample collection channel along a length between the proximal and distal ends of the sample collection channel; and
a linear array of detectors configured to scan a line across the assay pad to detect the reaction.
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Accused Products
Abstract
Arrangements for the detection of the presence and/or concentration of an analyte in a sample of bodily fluid include diffuse transmission, diffuse reflection and edge or waveguide illumination arrangements. A vertical flow assay arrangement and/or technique is also disclosed, and includes a detection component that can be in the form of an array of optical detection elements. A number of assay pad constructions are described which may include at least one or more of the following components: a prefilter component, a reflective component, a membrane component, a reagent component, a mesh component, and a component to prevent lateral spreading.
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Citations
8 Claims
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1. A device for conducting an assay to determine the concentration of an analyte in a sample of bodily fluid, the device comprising:
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a microneedle configured to collect the sample and comprising a lumen therethrough; an elongate sample collection channel transverse to the lumen of the microneedle, wherein the sample collection channel comprises a proximal end and a distal end, and wherein the proximal end is in communication with the lumen of the microneedle; an assay pad comprising a reagent that produces a reaction when exposed to the analyte, wherein the assay pad is in communication with the sample collection channel along a length between the proximal and distal ends of the sample collection channel; and a linear array of detectors configured to scan a line across the assay pad to detect the reaction. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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Specification