Invasive cardiac valve

• US 9,095,431 B2
• Filed: 12/30/2010
• Issued: 08/04/2015
• Est. Priority Date: 12/30/2009
• Status: Active Grant

• Current Assignee: Shanghai Microport Cardioflow Medtech Co., Ltd. (MicroPort Scientific Corp.)
• Original Assignee: Shanghai MicroPort Medical (Group) Co., Ltd. (MicroPort Scientific Corp.)
• Inventors: Yu, Qifeng, Yue, Chengyun, Luo, Qiyi, Liu, Xiang, Wang, Yunlei
• Primary Examiner(s): Sweet, Thomas J
• Assistant Examiner(s): DUKERT, BRIAN AINSLEY
• Application Number:
  US13/519,930
• Publication Number:
  US 20120316642A1
• Time in Patent Office: 1,678 Days
• Field of Search: 623/1.26, 623/2.17, 623/2.18
• US Class Current: 1/1
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2415 Manufacturing methods
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2002/3021 frustoconical
• CPC Class Codes: A61F 2002/9528 for retrieval of stents
• CPC Class Codes: A61F 2002/9534 for repositioning of stents
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0021 square
• CPC Class Codes: A61F 2230/0023 triangular
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0039 differing in diameter

Abstract

An invasive cardiac valve comprises a tubular stent (1) and a valve (2). One end of the tubular stent (1) is of a frusto-conical structure, the other end is wide open, and the diameter of the open end is greater than the diameter of the frusto-conical end. The valve (2) is attached to the frusto-conical end of the tubular stent (1); and a delivery and retrieval hole (4) of the cardiac valve is provided at the top of the open end of the tubular stent (1). Because the diameter of the open end is greater than the diameter of the frusto-conical end, the cardiac valve can be effectively fixed in a position of aortic annulus to prevent the cardiac valve displacement caused by the impact of the blood flow. Because the valve (2) is attached to the frusto-conical end of the tubular stent (1), the valve (2) can totally avoid the left and right coronary ostia and does not affect the haemodynamics of the coronary artery. Because a delivery and retrieval hole (4) of the cardiac valve is provided at the top of the open end of the tubular stent (1), the cardiac valve can be retrieved and reset at any time by handle control if it is found to be placed in an improper position during the release process.

Claims

1. An invasive cardiac valve having a top end and a bottom end, comprising a tubular stent and a valve, characterized in that

a first portion of the tubular stent is of a frusto-conical structure and defines a first end, a second portion of the tubular stent defines a wide open second end, the second portion of the tubular stent includes three rhombic grids which expand towards the second end in a petal shape, and the diameter of the second end is greater than the diameter of the first end, wherein the three rhombic grids of the tubular stent are composed of stent rods, and the thickness of the stent rods gradually decreases from the second end to the first end;

the valve is attached to the first end of the tubular stent;

a delivery and retrieval hole of the cardiac valve is provided at the second end of the tubular stent, wherein there are three delivery and retrieval holes of the cardiac valve, which are provided at the second end of the three rhombic grids respectively;

a frusto-cone generatrix of the first end of the tubular stent is a straight line, a circular arc or a combination of a straight line and a circular arc;

the cardiac valve defines at least two stent units, the at least two stent units gradually becoming smaller from the top end to the bottom end;

the valve is embodied as a leaflet and a skirt, and the leaflet and the skirt are designed as an integral structure;

the valve is sewed on the grids of the tubular stent, and a middle part of the valve is sewed with a transverse arc line using a suture line; and

the transverse arc line is sutured with the grids of the stent.

2. The invasive cardiac valve according to claim 1, characterized in that the tubular stent is of a grid structure composed of a plurality of rhombic stent units.

3. The invasive cardiac valve according to claim 1, characterized in that the portions of the rhombic grids positioned at the second end and at a location spaced from the second end are of an open structure, and the portion of the rhombic grids of the tubular stent between the second end and the location spaced from the second end are of a closed structure.

4. The invasive cardiac valve according to claim 1, characterized in that each of the three rhombic grids at the second end has a size that is greater than the diameter of the left and right coronary arteries.

5. The invasive cardiac valve according to claim 1, characterized in that the tubular stent is made of a nickel-titanium alloy material.

6. The invasive cardiac valve according to claim 1, characterized in that the valve is fixed inside the tubular stent by means of sewing using a suture line.

7. The invasive cardiac valve according to claim 1, characterized in that the leaflet and the skirt can be made of a biological tissue, a polymer material, a metallic material or a tissue engineered valve.

8. The invasive cardiac valve according to claim 1, characterized in that the skirt is of a frusto-conical shape sewed by three skirt base bodies of a same trapezoidal shape.

9. The invasive cardiac valve according to claim 1, characterized in that the valve can be made of a biological tissue, a polymer material, a metallic material or a tissue engineered valve.

10. The invasive cardiac valve according to claim 1, characterized in that the valve is formed by three valve base bodies of the same shape;

at one end of the valve base body, both sides are provided with leaflet suture ears, which are sewed on the tubular stent;

roots of any two adjacent leaflet suture ears are sewed together.

11. The invasive cardiac valve according to claim 1, characterized in that the tubular stent further includes a plurality of grids including the three rhombic grids.

12. The invasive cardiac valve according to claim 1, characterized in that the cardiac valve further includes a plurality of grids including the three rhombic grids.