Adjustable orthopedic implant and method for treating an orthopedic condition in a subject

• US 9,095,436 B2
• Filed: 04/14/2009
• Issued: 08/04/2015
• Est. Priority Date: 04/14/2009
• Status: Expired due to Fees

• Current Assignee: Gearbox LLC (Intellectual Ventures LLC)
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Boyden, Edward S., Della Rocca, Gregory J., Hyde, Roderick A., Kare, Jordin T., Leuthardt, Eric C., Santiago, Paul, Stewart, Todd J.
• Primary Examiner(s): Bates, David
• Assistant Examiner(s): HANNA, SAMUEL SALEEB
• Application Number:
  US12/386,269
• Publication Number:
  US 20100262239A1
• Time in Patent Office: 2,303 Days
• Field of Search: 606251-260, 606/299, 606/320, 606/282, 606/279, 606/900, 606/61, 623/2.73, 623/2.39, 623 1311- 2219, 623/23.45, 623/23.47, 623/38, 623/45, 623/11.11
• US Class Current: 1/1
• CPC Class Codes: A61B 17/68 Internal fixation devices , including fasteners and spinal fixators, even if a part thereof projects from the skin bone staples A61B17/0642
• CPC Class Codes: A61F 2/30 Joints
• CPC Class Codes: A61F 2/32 for the hip
• CPC Class Codes: A61F 2/38 for elbows or knees
• CPC Class Codes: A61F 2/40 for shoulders
• CPC Class Codes: A61F 2/42 for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
• CPC Class Codes: A61F 2/44 for the spine, e.g. vertebrae, spinal discs
• CPC Class Codes: A61F 2/48 Operating or control means, e.g. from outside the body, control of sphincters
• CPC Class Codes: A61F 2002/30537 adjustable
• CPC Class Codes: A61F 2002/3067 for data transfer
• CPC Class Codes: A61F 2002/4666 for measuring force, pressure or mechanical tension
• CPC Class Codes: A61F 2250/0002 for data transfer
• CPC Class Codes: A61F 2250/0004 adjustable

Abstract

An orthopedic implant is described including at least one adjustment mechanism configured for securing to at least one orthopedic structure of a subject, and at least one motor operatively connected to the at least one adjustment mechanism, wherein the at least one motor is configured to move the at least one adjustment mechanism in at least three degrees of freedom.

Claims

1. An orthopedic implant comprising:

at least one adjustment mechanism configured for securing to at least one orthopedic structure of a subject, the at least one adjustment mechanism consisting of tension band wiring in combination with one or more of pins, screws, or intramedullary nails or rods;

at least six one motors directly connected to the at least one adjustment mechanism, wherein the at least six motors are configured to move the at least one adjustment mechanism in six degrees of freedom;

at least one ultrasonic actuator operably connected to the at least six motors, the ultrasonic actuator is operable to power the at least six motors from an energy source configured to be remote from the orthopedic implant and operably coupled to the at least one ultrasonic actuator via ultrasonic energy;

a controller and a transmitter;

a sensor in communication with the controller and the transmitter, the sensor including circuitry for detecting a change in at least one of strain, pressure, or position of the at least one adjustment mechanism of the orthopedic implant when operably secured to the at least one orthopedic structure;

the transmitter including circuitry for transcutaneously reporting to a network configured to be remote from the orthopedic implant, information from the sensor indicative of the detected change;

the controller including circuitry for receiving energy from the remote energy source operably coupled to the at least one ultrasonic actuator via ultrasonic energy to remotely power the at least one motor to move the at least one adjustment mechanism of the orthopedic implant responsive to receiving reporting information indicative of the detected change in the at least one adjustment mechanism; and

the controller including circuitry for transcutaneously receiving control commands from the remote network to the controller to cause movement of the at least one adjustment mechanism responsive to reporting information from the sensor and the transmitter indicative of the detected change to adjust the curvature of the at least one orthopedic structure.

2. The implant of claim 1, wherein the controller including the circuitry for transcutaneously receiving control commands to cause movement of the at least one adjustment mechanism includes the controller configured to receive an input signal from the transmitter to actuate the at least six motors.

3. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of strain, pressure, or position of the orthopedic structure includes the sensor configured to send an input signal to the transmitter.

4. The implant of claim 1, wherein the controller including the circuitry for transcutaneously receiving control commands includes the controller configured to control actuation of the at least six motors configured to maintain the at least one orthopedic structure in a defined position.

5. The implant of claim 1, wherein the controller including the circuitry for transcutaneously receiving control commands includes the controller configured to control actuation of the at least six motors to execute a sequence of two or more defined configurational changes to the at least one adjustment mechanism.

6. The implant of claim 1, wherein the controller including the circuitry for transcutaneously receiving control commands includes the controller configured to receive an input signal originating from human input.

7. The implant of claim 1, wherein the controller including the circuitry for transcutaneously receiving control commands includes the controller configured to receive an input signal originating from data input.

8. The implant of claim 7, wherein the data input is X-ray data, magnetic resonance imaging data, or ultrasound data.

9. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of a strain, a pressure, or a position of an orthopedic structure includes the sensor configured to inform the controller in response to a sensed condition of the orthopedic structure.

10. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of strain, pressure, or position of an orthopedic structure includes a strain gauge, accelerometer, piezoelectric film, Hall effect sensor, linear variable displacement transducer (LVDT), differential variable reluctance transducer (DVRT), or reed switch sensor.

11. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of strain, pressure, or position of an orthopedic structure includes a sensor configured to detect health or integrity of the orthopedic structure.

12. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of strain, pressure, or position of an orthopedic structure includes the sensor configured to detect ultrasound through the orthopedic structure or conductivity of the orthopedic structure.

13. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of strain, pressure, or position of the orthopedic structure includes the sensor configured to detect an osteogenic cell marker.

14. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of strain, pressure, or position of the orthopedic structure includes the sensor configured to detect an osteogenic cell marker on a mesenchymal stem cell or osteoblast.

15. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of strain, pressure, or position of the orthopedic structure includes the sensor configured to detect alkaline phosphatase, osteocalcin, CBFA1/Osf2, or collagen 1A1.

16. The implant of claim 1, wherein the transmitter including the circuitry for transcutaneously reporting information indicative of the detected change to the remote network includes the transmitter in communication with the sensor and the controller, the transmitter configured to report activity of the implant to an external source.

17. The implant of claim 1, wherein the transmitter including the circuitry for transcutaneously reporting information indicative of the detected change to the remote network includes the transmitter configured to report activity of the implant to the remote network including a sensed condition of the orthopedic structure.

18. The implant of claim 1, wherein the transmitter including the circuitry for transcutaneously reporting information indicative of the detected change to the remote network includes the transmitter in communication with the sensor and the controller, the transmitter configured to send an actuation signal to the at least six motors.

19. The implant of claim 1, wherein the at least six motors are configured to be remotely-actuated from outside a body of a subject.

20. The implant of claim 1, wherein at least one of the at least six motors includes at least one of an electronic motor, electrostrictive motor, piezoelectric motor, ultrasonically-activated motor, shape memory alloy actuator, paraffin actuator, electromagnetic solenoid, or electroactive polymer.

21. The implant of claim 1, wherein at least one of the at least six motors includes a stepper motor, drive motor, or servomotor.

22. The implant of claim 1, wherein at least one of the at least six motors includes a piezoelectric stepper motor.

23. The implant of claim 1, wherein at least one of the at least six motors includes an ultrasonic lead screw motor.

24. The implant of claim 1, wherein the at least six motors includes an ultrasonically-activated motor configured to controllably move the at least one adjustment mechanism in at least six degrees of freedom to adjust curvature of the at least one orthopedic structure, wherein the orthopedic structure is a femur.

25. The implant of claim 1, wherein the at least six motors are configured to controllably move the at least one adjustment mechanism in at least six degrees of freedom to lengthen the at least one orthopedic structure, shorten the at least one orthopedic structure, tighten the at least one orthopedic structure, apply compression to the at least one orthopedic structure, twist the at least one orthopedic structure, shear the at least one orthopedic structure, increase or decrease stress or load on the at least one orthopedic structure.

26. The implant of claim 1, wherein the at least one adjustment mechanism is configured to be incrementally adjusted.

27. The implant of claim 1, wherein the orthopedic structure is bone.

28. The implant of claim 1, wherein the at least one adjustment mechanism is configured to be attached at a bone fracture site, bone graft, or fused bone.

29. The implant of claim 1, wherein at least one of the at least six motors is powered from an internal energy source including battery, capacitor, or mechanical storage.

33. The implant of claim 1, wherein the sensor including the circuitry for detecting the change in at least one of strain, pressure, or position of an orthopedic structure includes the sensor configured to detect flexibility or stiffness of the orthopedic implant.

30. A system comprising:

an indwelling orthopedic implant including;

at least one adjustment mechanism configured for securing to at least one orthopedic structure of a subject, the at least one adjustment mechanism consisting of tension band wiring in combination with one or more of pins, screws, or intramedullary nails or rods;

at least six motors directly connected to the at least one adjustment mechanism, wherein the at least six motors are configured to move the at least one adjustment mechanism in six degrees of freedom;

an energy source configured to be remote from the orthopedic implant and operably coupled to at least one ultrasonic actuator via ultrasonic energy to remotely power the at least six motors directly connected to the at least one adjustment mechanism;

wherein the at least one ultrasonic actuator is operably connected to the at least six motors, and the at least one ultrasonic actuator is operable to power the at least six motors from the remote energy source operably coupled via ultrasonic energy;

a controller and a transmitter;

a sensor in communication with the controller and the transmitter, the sensor including circuitry for detecting a change in an applied force or a change in position of the at least one adjustment mechanism when operably secured to a bone fracture site of a limb of a subject;

the controller including circuitry for transcutaneously receiving energy from the remote energy source operably coupled to the at least one ultrasonic actuator via ultrasonic energy to remotely power the at least motors directly connected to the at least one adjustment mechanism of the indwelling orthopedic implant responsive to reporting information from the sensor to the transmitter indicative of the detected change in an applied force or a change in position of the at least one adjustment mechanism when operably secured to the bone fracture site of the limb of the subject; and

the controller including circuitry for actuating the at least one adjustment mechanism in at least six degrees of freedom to adjust curvature of the limb of the subject responsive to reporting information indicative of the detected change in the applied force or the change in position of the at least one adjustment mechanism when operably secured to the bone fracture site of the limb of the subject.

31. The system of claim 30, wherein the controller including the circuitry for actuating the at least one adjustment mechanism includes the controller configured to receive an input signal from the transmitter to actuate the at least six motors.

32. The system of claim 31, wherein the sensor including the circuitry for detecting the change in an applied force or the change in position includes the sensor configured to send the input signal to the transmitter and to inform the controller in response to a sensed condition of the at least one adjustment mechanism.