Device and system for determining, preparing and administering therapeutically effective doses

• US 9,095,495 B2
• Filed: 02/24/2010
• Issued: 08/04/2015
• Est. Priority Date: 02/24/2010
• Status: Active Grant

• Current Assignee: Aquestive Therapeutics, Inc.
• Original Assignee: Monosol Rx LLC (Kuraray Company Limited)
• Inventors: Bogue, Beuford A.
• Primary Examiner(s): COLLINS, MICHAEL
• Application Number:
  US12/711,899
• Publication Number:
  US 20110208348A1
• Time in Patent Office: 1,987 Days
• Field of Search: 700/237, 700/240
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0095 by applying light and detecting acoustic waves, i.e. photoacoustic measurements
• CPC Class Codes: A61J 2200/44 Cooling means
• CPC Class Codes: A61J 7/0076 Medicament distribution means with pill counting devices A61J7/02; with time indication A61J7/04; containers or packages with special means for dispensing contents B65D83/00
• CPC Class Codes: A61J 7/0084 for multiple medicaments
• CPC Class Codes: G07F 17/0092 for assembling and dispensing of pharmaceutical articles medical dispensers for private use, A61J7/00
• CPC Class Codes: G16H 20/13 delivered from dispensers
• CPC Class Codes: G16H 20/60 relating to nutrition control, e.g. diets

Abstract

The present invention relates to a system and method for dispensing a therapeutically effective amount of dosage containing a medicament including an instrument for inputting data from a user, analyzing the inputted data to determine an appropriate amount of medicament to be administered to the user, and a dispenser for sizing and dispensing a therapeutically effective amount of the medicament. The medicament may be in the form of a continuous roll of oral thin film including the medicament.

Claims

1. A system for dispensing an amount of film containing a medicament comprising:

a. an instrument for inputting contemporaneously produced user related data from a user;

b. a processor for analyzing said inputted contemporaneously produced user related data to determine an appropriate and therapeutically effective amount of medicament required by the user at the time at which the user uses the system;

c. an instrument for producing an output signal;

d. a housing for storing a continuous roll of film, said film comprising a medicament in a known amount of medicament per unit volume of film;

e. an instrument for receiving said output signal and determining an amount of film which includes said appropriate amount of medicament to be administered to said user; and

f. a dispenser for sizing and dispensing said amount of film.

2. The system of claim 1, wherein said data comprises manually entered data.

3. The system of claim 1, wherein said data comprises chemical data.

4. The system of claim 3, wherein said chemical data comprises a bodily fluid.

5. The system of claim 4, wherein said bodily fluid comprises saliva, blood, urine, mucous material, tears, perspiration, and combinations thereof.

6. The system of claim 4, wherein said instrument for inputting data from a user comprises a means for accepting said bodily fluid.

7. The system of claim 1, wherein said data comprises information selected from the group consisting of information related to food consumed by said user, information related to food to be consumed by said user, information related to the level of pain experienced by said user, information related to the body temperature of said user, information related to the level of allergic reaction experienced by the user, blood clotting time, prothrombin time, platelet count, and combinations thereof.

8. The system of claim 1, wherein said processor comprises internal memory.

9. The system of claim 8, wherein said memory includes stored data.

10. The system of claim 9, wherein said stored data comprises information related to said user.

11. The system of claim 10, wherein said information related to said user comprises information selected from the group consisting of the user'"'"'s age, the user'"'"'s height, the user'"'"'s weight, user'"'"'s sex, user'"'"'s ethnic origin, users medical history, the typical body temperature of the user, the last time medicament was administered to said user, the amount of medicament last administered to said user, maximum allowable dosage of medicament, historical data of medicament administration for the duration of the film cartridge and combinations thereof.

12. The system of claim 9, wherein said processor analyzes said inputted data and said stored data to determine an appropriate amount of medicament to be administered to said user.

13. The system of claim 1, wherein said appropriate amount of medicament to be administered to said user is the amount of medicament necessary to treat a condition experienced by said user.

14. The system of claim 13, wherein said condition comprises pain.

15. The system of claim 13, wherein said condition comprises fever.

16. The system of claim 13, wherein said condition comprises a blood sugar level.

17. The system of claim 13, wherein said condition comprises an insulin level.

18. The system of claim 13, wherein said condition comprises a platelet level.

19. The system of claim 13, wherein said condition comprises a blood clotting time.

20. The system of claim 13, wherein said condition comprises a prothrombin time.

21. The system of claim 1, wherein said output signal comprises the appropriate amount of medicament to be administered to said user.

22. The system of claim 21, wherein said instrument for producing an output signal comprises a display.

23. The system of claim 22, wherein said display conveys the appropriate amount of medicament to be administered to said user.

24. The system of claim 1, wherein said continuous roll of film has a protective layer.

25. The system of claim 1, wherein said housing is moisture-impermeable.

26. The system of claim 1, wherein said housing is heat-impermeable.

27. The system of claim 1, wherein said housing is light-impermeable.

28. The system of claim 1, wherein said housing is maintained at a desired temperature.

29. The system of claim 28, wherein said housing comprises a cooler.

30. The system of claim 1, wherein said amount of film needed to provide the appropriate amount of medicament to be administered to said user comprises a volume of film.

31. The system of claim 30, wherein said instrument for receiving said output signal determines the length of film to provide said volume of oral thin film.

32. The system of claim 1, wherein said dispenser is in communication with said housing, such that said amount of film may be dispensed from said housing through said dispenser.

33. The system of claim 32, wherein said dispenser comprises a port, which is sized to allow said film to pass therethrough.

34. The system of claim 33, wherein said port comprises a removable cover.

35. The system of claim 34, wherein said removable cover is automatically moved when said film is being dispensed.

36. The system of claim 34, wherein said removable cover may manually be removed to dispense said film.

37. The system of claim 33, wherein said dispenser comprises a cutting means.

38. The system of claim 37, wherein said cutting means is used to cut said film to the appropriate length so as to provide the amount of medicament needed.

39. The system of claim 1, wherein said medicament comprises a biologic.

40. The system of claim 1, wherein said medicament comprises insulin.

41. The system of claim 1, wherein said medicament comprises an analgesic.

42. The system of claim 1, wherein said medicament comprises a blood clotting agent.

43. The system of claim 1, wherein said instrument for inputting data and said housing are connected via a wire.

44. The system of claim 1, wherein said instrument for inputting data and said housing are housed in one unit.

45. The system of claim 44, wherein said housing is hand-held.

46. The system of claim 45, wherein said housing is pocket sized.

47. The system of claim 1, wherein said roll of film is housed in a cartridge.

48. The system of claim 47, wherein said cartridge is replaceable in said housing.