Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer
First Claim
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1. An ophthalmic composition comprising:
- 0.01 wt. % to 2 wt. % of an amphoteric surfactant of general formula I
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Abstract
Ophthalmic compositions that comprise 0.1 ppm to 50 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0.005 wt. % to 2 wt. % of an anionic biopolymer; and 0.01 wt. % to 2 wt. % of an amphoteric surfactant of general formula I
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- wherein R1 is R or —(CH2)n—NHC(O)R, wherein R is a C8-C30alkyl optionally substituted with hydroxyl and n is 2, 3 or 4; R2 and R3 are each independently selected from C1-C4alkyl; R4 is a C2-C8alkylene optionally substituted with hydroxyl; and Y is CO2− or SO3. The invention is also direct to the use of the ophthalmic compositions to clean and disinfect contact lenses, and in particular, soft, silicone hydrogel contact lenses.
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16 Claims
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1. An ophthalmic composition comprising:
0.01 wt. % to 2 wt. % of an amphoteric surfactant of general formula I - View Dependent Claims (2, 3, 4, 5, 6, 11, 13, 15, 16)
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7. An ophthalmic composition comprising:
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0.5 ppm to 1.8 ppm of poly(hexamethylene biguanide); 0.5 ppm to 2 ppm α
-[4-tris(2-hydroxyethyl)-ammonium chloride-2-butenyl]poly[1-dimethyl ammonium chloride-2-butenyl]-ω
-tris(2-hydroxyethyl) ammonium chloride;0.002 wt. % to 0.03 wt. % hyaluronic acid; 0.01 wt. % to 0.05 wt. % ethylenediaminetetraacetic acid or a corresponding salt thereof; a borate buffer; and 0.01 wt. % to 0.8 wt. % of an amphoteric surfactant of general formula I - View Dependent Claims (8, 9, 10, 12, 14)
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Specification