Determining systolic time intervals using heart sounds
First Claim
1. A system comprising:
- an acoustic energy sensor, configured to sense an acoustic signal of a subject;
a heart sound detector circuit, configured to detect a heart sound signal using the acoustic signal;
a physiological signal sensing circuit configured to detect a physiological pulsatile signal associated with the subject'"'"'s pulse and including a pulsatile cervical impedance signal;
a timing circuit, coupled to the heart sound detector circuit and the physiological signal sensing circuit, configured to calculate a time interval between a feature on the heart sound signal and a feature on the pulsatile signal; and
at least one of an ambulatory medical device or an adjunct device including a diagnostic circuit configured to determine a physiologic diagnostic indication using information provided by the timing circuit about the time interval between the feature on the heart sound signal and the feature on the pulsatile signal.
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Accused Products
Abstract
Systems and methods are provided for using information from a subject heart sound signal and information from a subject physiological pulsatile signal to identify subject systolic time intervals. An example system for identifying systolic time intervals includes a heart sound detector circuit, configured to detect a subject heart sound signal using an acoustic signal. The system can include a physiological signal sensing circuit configured to detect a physiological pulsatile signal, including at least one of a pulsatile cervical impedance signal or a pulsatile pulmonary artery pressure signal. A timing circuit can be configured to calculate a systolic time interval between a feature on the heart sound signal and a feature on the pulsatile signal. A subject physiologic diagnostic indication can be provided using information from the timing circuit about the systolic time interval.
26 Citations
18 Claims
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1. A system comprising:
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an acoustic energy sensor, configured to sense an acoustic signal of a subject; a heart sound detector circuit, configured to detect a heart sound signal using the acoustic signal; a physiological signal sensing circuit configured to detect a physiological pulsatile signal associated with the subject'"'"'s pulse and including a pulsatile cervical impedance signal; a timing circuit, coupled to the heart sound detector circuit and the physiological signal sensing circuit, configured to calculate a time interval between a feature on the heart sound signal and a feature on the pulsatile signal; and at least one of an ambulatory medical device or an adjunct device including a diagnostic circuit configured to determine a physiologic diagnostic indication using information provided by the timing circuit about the time interval between the feature on the heart sound signal and the feature on the pulsatile signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A process comprising:
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measuring a physiological pulsatile signal with an ambulatory medical device, the physiological pulsatile signal associated with a subject'"'"'s pulse and including a pulsatile cervical impedance signal; measuring a heart sound signal with the ambulatory medical device; calculating, using the ambulatory medical device or an adjunct device that is communicatively coupled thereto, a time interval between a feature on the physiological pulsatile signal and a feature on the heart sound signal; and determining a physiologic diagnostic indication using information about the time interval between the feature on the physiological pulsatile signal and a feature on the heart sound signal. - View Dependent Claims (15, 16, 17)
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18. A system comprising:
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an electrical signal sensing circuit, configured to sense an electrical signal from a subject; a physiological signal sensing circuit configured to detect a pulsatile cervical impedance signal, the impedance signal indicative of dimensional changes of a subject carotid artery; a timing circuit, coupled to the electrical signal sensing circuit and the physiological signal sensing circuit, configured to calculate a time interval between a feature on the electrical signal and a feature on the pulsatile cervical impedance signal; and at least one of an ambulatory medical device or an adjunct device including a diagnostic circuit configured to determine a physiologic diagnostic indication using information provided by the timing circuit about the time interval between the feature on the electrical signal and the feature on the pulsatile cervical impedance signal; wherein the timing circuit is configured to calculate the time interval between a Q-wave fiducial or an R-wave fiducial on the electrical signal and a feature on the pulsatile cervical impedance signal, the feature on the pulsatile cervical impedance signal corresponding to an onset of an ejection period.
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Specification