Valve prosthesis

• US 9,101,467 B2
• Filed: 03/30/2012
• Issued: 08/11/2015
• Est. Priority Date: 03/30/2012
• Status: Active Grant

• Current Assignee: Medtronic CV Luxembourg SARL (Medtronic Plc)
• Original Assignee: Medtronic CV Luxembourg SARL (Medtronic Plc)
• Inventors: McNatt, Tomas, Eberhardt, Carol, Lo, Pham
• Primary Examiner(s): Nguyen, Tuan V
• Assistant Examiner(s): NGUYEN, TIN DUC
• Application Number:
  US13/435,802
• Publication Number:
  US 20130261740A1
• Time in Patent Office: 1,229 Days
• Field of Search: 623/2.11, 623/2.37
• US Class Current: 1/1
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: F04C 2270/0421 Controlled or regulated

Abstract

Heart valve prostheses are provided having a self-expanding frame that supports a valve body comprising a plurality of coapting leaflets. The valve body may include a first leaflet, a second leaflet, and a third leaflet, wherein the second leaflet extends between the first leaflet and the third leaflet such that the first and third leaflets are separated from each other by the second leaflet. The leaflets are constructed with four commissure points to reduce the stress and strain applied to the commissure points and to efficiently distribute forces along the leaflets and to the frame. As such, the first and second leaflets may be sewn together to form a first commissure point and a second commissure point, and the second and third leaflets may be sewn together to form a third commissure point and a fourth commissure point, with the four commissure points being sewn to the frame.

Claims

1. A valve prosthesis comprising:

a valve body; and

a self-expanding frame,

wherein the valve body includes a first leaflet, a second leaflet, and a third leaflet, wherein the second leaflet extends between the first leaflet and the third leaflet such that the first and third leaflets are separated from each other by the second leaflet and wherein the first and second leaflets are sewn together to form a first commissure point and a second commissure point, and the second and third leaflets are sewn together to form a third commissure point and a fourth commissure point, and wherein the four commissure points are sewn to the frame.

2. The valve prosthesis according to claim 1, wherein a first angle is formed between the first commissure point and the second commissure point with a vertex of the first angle being a center of the frame, a second angle is formed between the second commissure point and the third commissure point with a vertex of the second angle being the center of the frame, a third angle is formed between the third commissure point and the fourth commissure point with a vertex of the third angle being the center of the frame, and a fourth angle is formed between the fourth commissure point and the first commissure point with a vertex of the fourth angle being the center of the frame such that the center of the frame is the vertex of each of the first, second, third and fourth angles, and wherein the first angle and the third angle are greater than the second angle and the fourth angle.

3. The valve prosthesis according to claim 2, wherein the first angle and the third angle are approximately equal.

4. The valve prosthesis according to claim 2, wherein the first angle and the third angle are approximately 170 degrees.

5. The valve prosthesis according to claim 2, wherein the first angle is greater than the third angle.

6. The valve prosthesis according to claim 2, wherein the second angle and the fourth angle are approximately equal.

7. The valve prosthesis according to claim 1, wherein a free edge of the first leaflet and a first free edge of the second leaflet form a first coaptive edge between the first commissure point and the second commissure point, and wherein a second free edge of the second leaflet and a free edge of the third leaflet form a second coaptive edge between the third commissure point and the fourth commissure point.

8. The valve prosthesis according to claim 7, wherein the first coaptive edge is approximately equal in length to the second coaptive edge.

9. The valve prosthesis according to claim 7, wherein the second coaptive edge is greater in length than the first coaptive edge.

10. The valve prosthesis according to claim 1, wherein the second leaflet extends across a center of the frame.

11. The valve prosthesis according to claim 10, further comprising:

a center member attached to the frame that extends across the second leaflet.

12. The valve prosthesis according to claim 11, wherein the center member is disposed on an outflow side of the second leaflet and is configured to restrict movement of the second leaflet in the presence of blood flow through the valve prosthesis.

13. The valve prosthesis according to claim 11, wherein a first end of the center member is attached to the frame between the first commissure point and the fourth commissure point and a second end of the center member is attached to the frame between the second commissure point and the third commissure point.

14. A method of treating a valve disorder in a patient'"'"'s heart, comprising:

loading a valve prosthesis onto a delivery system;

advancing the delivery system and valve prosthesis through an incision into the patient'"'"'s vasculature and into the patient'"'"'s heart;

releasing the valve prosthesis from the delivery system; and

withdrawing the delivery system from the patient'"'"'s heart,

wherein the valve prosthesis includes;

a valve body; and

a self-expanding frame,

wherein the valve body includes a first leaflet, a second leaflet, and a third leaflet, wherein the second leaflet extends between the first leaflet and the third leaflet such that the first and third leaflets are separated from each other by the second leaflet and wherein the first and second leaflets are sewn together to form a first commissure point and a second commissure point, and the second and third leaflets are sewn together to form a third commissure point and a fourth commissure point, and wherein the four commissure points are sewn to the frame.