Non-immediate effects of therapy
First Claim
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1. A method of treating a metabolic condition in a patient, comprising:
- determining a target non-immediate effect of a therapy relating to treatment of a metabolic condition, said target including a reduced fasting glucose level identifiable 24 hours after said applying is stopped;
selecting an application protocol designed to at least approach said target;
applying an electric field to an abdominal cavity of the patient following said protocol so as to at least approach said target; and
causing said target to be approached by said applying, wherein said non-immediate effect is in addition to any effect caused by weight loss.
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Abstract
A method of treating a metabolic condition in a patient, comprising:
- determining a target non-immediate effect of a therapy relating to treatment of a metabolic condition; and
- applying an electric field to an abdominal cavity of the patient in a manner designed to at least approach said target.
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Citations
50 Claims
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1. A method of treating a metabolic condition in a patient, comprising:
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determining a target non-immediate effect of a therapy relating to treatment of a metabolic condition, said target including a reduced fasting glucose level identifiable 24 hours after said applying is stopped; selecting an application protocol designed to at least approach said target; applying an electric field to an abdominal cavity of the patient following said protocol so as to at least approach said target; and causing said target to be approached by said applying, wherein said non-immediate effect is in addition to any effect caused by weight loss. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. Apparatus for treating a metabolic disorder, comprising:
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at least one electrode adapted for implantation in an abdominal cavity; and circuitry configured to apply an electrical signal, suitable for acute metabolic treatment of humans by reducing blood glucose levels, to said electrodes fewer than 3 hours a day, on the average for a month, wherein said configuration comprises a limit on application duration in a day. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. Apparatus for treating a metabolic disorder, comprising:
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at least one electrode adapted for implantation in an abdominal cavity; and circuitry configured to apply an electrification signal, suitable for acute metabolic treatment of humans by reducing blood glucose levels, to said at least one electrode less than once a day on the average for at least a week, wherein said configuration comprises a limit on application duration in a day. - View Dependent Claims (42)
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43. A method of metabolic treatment, comprising:
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determining a desired diurnal day and night blood glucose level pattern which is not uniform over the day; applying a blood chemical modifying electrical therapy in a pattern selected to at least approach said desired diurnal pattern by the application separately affecting day and night blood glucose levels.
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44. A method of treating an early morning rise in blood glucose levels including one or both of a dawn effect and a Somogyi effect, comprising:
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predicting an increase in blood glucose levels at a time prior to an expected waking time; and applying an electric field to an abdominal cavity of a patient more than 2 hours before said expected waking time and prior to said predicted increase, said applying preventing or reducing such an increase in blood glucose level. - View Dependent Claims (45)
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46. A method for determining a suitability of a patient for treatment using electrical therapy, comprising:
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applying at least one electrical field to the patient, said field at least putatively suitable for achieving a metalobic change of a non-immediate reduced fasting glucose level identifiable after 24 hours; and determining a suitablility of said patient, based on at least one of (a) a change in response to a metabolic challenge given after the applying, said change caused by said field; and
(b) a non-immediate effect of said field measured at least 24 hours after said applying is stopped. - View Dependent Claims (47, 48, 49)
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50. A method of treating a variation in blood glucose level, comprising:
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predicting a change in blood glucose level based on a pattern of blood glucose levels; and applying an electric field to an abdominal cavity of a patient more than 1 hour before a predicted increase in blood glucose levels, said applying preventing or reducing such an increase in blood glucose level.
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Specification