×

Automatic isothermal titration microcalorimeter apparatus and method of use

  • US 9,103,782 B2
  • Filed: 12/02/2008
  • Issued: 08/11/2015
  • Est. Priority Date: 12/02/2008
  • Status: Active Grant
First Claim
Patent Images

1. An automated isothermal titration micro calorimetry (ITC) system arranged to perform a plurality of unattended titration experiments in series, the system comprising:

  • a system controller for controlling the automated operation of the ITC a micro calorimeter comprising a sample cell and a reference cell, the sample cell being accessible via a sample cell stem and the reference cell being accessible via a reference cell stem;

    an automatic pipette assembly comprising a syringe with a titration needle arranged to be inserted into the sample cell for supplying titrant, the pipette assembly comprising an activator for driving a plunger in the syringe cavity;

    a wash station;

    a sample fill station;

    a pipette translation unit supporting the pipette assembly that places a pipette in position for titration with the titration needle in the sample cell and in position for washing and filling operations with the titration needle in the wash station and the sample fill station;

    a cell preparation unit that performs operations for replacing the sample liquid in the sample cell when the pipette is placed in another position than the position for titration.

View all claims
  • 3 Assignments
Timeline View
Assignment View
    ×
    ×