Laser illumination systems and methods for dual-excitation wavelength non-linear optical microscopy and micro-spectroscopy systems
First Claim
1. An illumination system for providing dual-excitation wavelength illumination for non-linear optical microscopy and micro-spectroscopy, said illumination system comprising:
- a laser system including a laser for providing a first train of pulses at a center optical frequency ω
1;
an optical splitting means for dividing the first train of pulses at the center optical frequency ω
1 into a first split train of pulses and a second split train of pulses;
a frequency shifting system for shifting the optical frequency of the first split train of pulses to provide a frequency shifted train of pulses;
an amplifier system for amplifying the frequency-shifted train of pulses to provide an amplified frequency-shifted train of pulses;
combining means for combining the amplified frequency-shifted train of pulses with the second split trains of pulses to provide the amplified frequency-shifted train of pulses and the second split trains of pulses as a collinear train of laser pulses for the dual-excitation wavelength illumination; and
adjustment means for adjusting a time delay between the amplified frequency-shifted train of pulses and the second split train of pulses.
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Abstract
An illumination system is disclosed for providing dual-excitation wavelength illumination for non-linear optical microscopy and micro-spectroscopy. The illumination system includes a laser system, an optical splitting means, a frequency shifting system, and a picosecond amplifier system. The laser system includes a laser for providing a first train of pulses at a center optical frequency ω1. The optical splitting means divides the first train of pulses at the center optical frequency ω1 into two trains of pulses. The frequency shifting system shifts the optical frequency of one of the two trains of pulses to provide a frequency shifted train of pulses. The picosecond amplifier system amplifies the frequency shifted train of pulses to provide an amplified frequency-shifted train of pulses having a pulse duration of at least 0.5 picoseconds.
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Citations
21 Claims
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1. An illumination system for providing dual-excitation wavelength illumination for non-linear optical microscopy and micro-spectroscopy, said illumination system comprising:
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a laser system including a laser for providing a first train of pulses at a center optical frequency ω
1;an optical splitting means for dividing the first train of pulses at the center optical frequency ω
1 into a first split train of pulses and a second split train of pulses;a frequency shifting system for shifting the optical frequency of the first split train of pulses to provide a frequency shifted train of pulses; an amplifier system for amplifying the frequency-shifted train of pulses to provide an amplified frequency-shifted train of pulses; combining means for combining the amplified frequency-shifted train of pulses with the second split trains of pulses to provide the amplified frequency-shifted train of pulses and the second split trains of pulses as a collinear train of laser pulses for the dual-excitation wavelength illumination; and adjustment means for adjusting a time delay between the amplified frequency-shifted train of pulses and the second split train of pulses. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification