Spectral imaging with a color wheel

• US 9,107,567 B2
• Filed: 12/27/2012
• Issued: 08/18/2015
• Est. Priority Date: 12/27/2012
• Status: Active Grant

• Current Assignee: Christie Digital Systems Canada Incorporated (Ushio Incorporated)
• Original Assignee: Christie Digital Systems USA Incorporated (Ushio Incorporated)
• Inventors: Pinho, George P.
• Primary Examiner(s): Le, Long V
• Assistant Examiner(s): PONTIUS, KEVIN LANE
• Application Number:
  US13/728,736
• Publication Number:
  US 20140187968A1
• Time in Patent Office: 964 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/441 Skin evaluation, e.g. for skin disorder diagnosis
• CPC Class Codes: A61B 6/00 Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment instruments measuring radiation intensity for application in the field of nuclear medicine, e.g. in vivo counting, G01T1/161; apparatus for taking X-ray photographs G03B42/02
• CPC Class Codes: G01N 2021/178 Methods for obtaining spatial resolution of the property being measured
• CPC Class Codes: G01N 2021/3144 for oxymetry
• CPC Class Codes: G01N 2021/3148 using three or more wavelengths
• CPC Class Codes: G01N 21/314 with comparison of measurements at specific and non-specific wavelengths dual wavelength spectrometry G01J3/427

Abstract

A spectral imaging apparatus includes an image sensor positioned to capture images of a target, a rotating color wheel aligned with the image sensor, and a projector positioned to project overlay images onto the target. The color wheel can include one or more filter segments, each allowing light of a different range of wavelengths to pass. The color wheel can further include a blocking or opaque segment. A set of captured images of the different wavelengths can be processed to generate a false-color overlay image for projection onto the target. Processing of overlay images can be performed when the blocking or opaque segment is in front of the image sensor. The spectral imaging apparatus may be a multi-spectral imaging apparatus and made be used in the medical fields, such as for determining and indicating tissue oxygenation. Video rates can be achieved.

Claims

1. A spectral video medical imaging apparatus comprising:

an illumination device arranged to illuminate a target tissue;

an image sensor arranged to capture light reflected from the target tissue along an imaging optical path;

a color wheel aligned with the image sensor on the imaging optical path, the color wheel configured to rotate at a predetermined frequency, the color wheel comprising at least one filter segment and at least one blocking segment;

a projector arranged to project overlay images along a projecting optical path and onto the target tissue, the projecting optical path at least partially overlapping the imaging optical path; and

a processor connected to the image sensor and the projector, the processor configured to generate the overlay images from light captured by the image sensor and to provide the overlay images to the projector for projection when the blocking segment blocks the imaging optical path;

wherein

the projection occurs intermittently and at different times than the capturing; and

the blocking segment is configured to block the light reflected from the target tissue along the imaging optical path from reaching the image sensor when the projector is projecting the overlay images.

2. The apparatus of claim 1, wherein the processor is further configured to, during a current cycle of the color wheel, encode a first image based on light captured by the image sensor during the current cycle and control the projector to project a first image encoded during a previous cycle of the color wheel that occurred earlier than the current cycle.

3. The apparatus of claim 1, wherein the filter segment is selected to match an absorption band of oxygenated hemoglobin.

4. The apparatus of claim 1, wherein the color wheel comprises two or more filter segments.

5. The apparatus of claim 4, wherein the filter segments are selected to have different wavelengths to match different absorption bands of oxygenated hemoglobin.

6. The apparatus of claim 1, wherein the color wheel comprises a single blocking segment.

7. The apparatus of claim 1, further comprising a filter arranged along the projecting optical path and the imaging optical path, the filter configured to reflect wavelengths of light that the filter segment of the color wheel transmits.

8. The apparatus of claim 7, wherein the filter is located at an intersection of the projecting optical path and the imaging optical path and the filter is oriented at about 45 degrees to both the projecting optical path and the imaging optical path.

9. The apparatus of claim 8, wherein the projecting optical path overlaps the imaging optical path between the filter and the target tissue.

10. The apparatus of claim 9, wherein the projecting optical path does not overlap the imaging optical path between the filter and the image sensor.

11. The apparatus of claim 1, further comprising an imaging lens, the color wheel being positioned between the image sensor and the imaging lens.

12. The apparatus of claim 11, further comprising at least one relay lens positioned between the color wheel and the image sensor.

13. The apparatus of claim 11, further comprising at least one relay lens positioned between the color wheel and the imaging lens.

14. The apparatus of claim 1, wherein the predetermined frequency of rotation of the color wheel is at least about 15 Hz.

15. A method of video imaging, the method comprising:

capturing images of a target tissue, the images being of different wavelength bands defined by a color wheel comprising at least one filter segment and at least one blocking segment;

processing captured images to generate overlay images;

projecting the overlay images onto the target tissue when the blocking segment blocks capturing images of the target tissue; and

timing the capturing, processing, and projecting according to the rotation of the color wheel to perform the projecting of a previously generated overlay image at least partially contemporaneously with the processing of current captured images;

wherein the projecting occurs intermittently and at different times than the capturing.

16. The method of claim 15, wherein the different wavelength bands are selected to match different absorption bands of oxygenated hemoglobin.

17. The method of claim 15, wherein the color wheel comprises a single blocking segment.

18. The method of claim 15, wherein the capturing and projecting are performed at least partially along a same optical path.

19. The method of claim 15, comprising rotating the color wheel at least about 15 Hz.

20. A spectral video imaging apparatus comprising:

a processor;

memory connected to the processor;

an image sensor connected to the processor, the image sensor positioned to capture images of a target;

a projector connected to the processor, the projector positioned to project overlay images onto the target; and

a color wheel aligned with the image sensor, the color wheel including a blocking segment and at least two filter segments of different wavelengths, the color wheel configured to rotate at a predetermined frequency;

the processor configured to process a set of images of the different wavelengths captured by the image sensor to generate a false-color overlay image, and provide the overlay image to the projector for projection onto the target;

wherein the projection occurs intermittently and at different times than the capturing; and

the blocking segment is configured to block the image capture when the projector is projecting the overlay images.

21. The apparatus of claim 20, wherein the processor is configured to process a set of images of the different wavelengths to generate a false-color overlay image and provide the overlay image to the projector according to predetermined video-rate frequency of rotation of the color wheel.