Embolic particle mixing syringe

• US 9,107,668 B2
• Filed: 03/20/2009
• Issued: 08/18/2015
• Est. Priority Date: 03/25/2008
• Status: Active Grant

• Current Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Inventors: Melsheimer, Jeffry S., Tekulve, Kurt J.
• Primary Examiner(s): Mehta, Bhisma
• Assistant Examiner(s): LEE, BRANDY SCOTT
• Application Number:
  US12/408,109
• Publication Number:
  US 20090247985A1
• Time in Patent Office: 2,342 Days
• Field of Search: 604 82- 92, 604/135, 604/226, 604/231, 604/506, 604/191, 604/246
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 2017/00495 for two-component glue
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2005/31598 having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/31505 Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit

Abstract

A syringe device for agitating and delivering a liquid medication to a patient is provided. The device includes an injecting member, a first syringe, a second syringe and an accumulator. The first syringe is configured to provide the liquid medication to the device. The second syringe is configured to receive the liquid medication from the first syringe. The accumulator is biased to an empty position and cooperates with the second syringe to agitate the liquid medication back and forth between the second syringe and the accumulator. The second syringe is configured to move the liquid medication to the injecting member for patient delivery.

Claims

1. A syringe device for agitating and delivering a liquid medication to a patient comprising:

an injecting member;

a first syringe configured to provide the liquid medication;

a second syringe in selective fluid communication with the injecting member and the first syringe, the second syringe being configured to receive the liquid medication from the first syringe and move the liquid medication to the injecting member for patient delivery, the second syringe also being coupled to the first syringe by a valve, the valve being selectively adjustable between a first position in which the first syringe is in fluid communication with the second syringe and a second position in which the first syringe is not in fluid communication with the second syringe; and

an accumulator in selective fluid communication with the second syringe, the accumulator being biased to an empty position to move the liquid medication to the second syringe by a biasing member, wherein the biasing member is one of a spring, foam, gas, balloon, elastomer, electromagnetic field, and gravity, wherein the biased accumulator cooperates with the second syringe to agitate the liquid medication between the second syringe and the accumulator prior to patient delivery.

2. The device of claim 1, further comprising a first valve coupling the first syringe to the second syringe and a second valve coupling the accumulator to the second syringe proximal the first valve, the first valve being selectively adjustable between a first position in which the first and second syringes are in fluid communication with each other and a second position in which the first and second syringes are not in fluid communication with each other, the second valve being selectively adjustable between a first position in which the accumulator and the second syringe are in fluid communication with each other and the second valve is not in fluid communication with the first valve, a second position in which the accumulator and the second syringe are in fluid communication with each other and the second valve is in fluid communication with the first valve, and a third position in which the accumulator and the second syringe are not in fluid communication with each other and the second valve is in fluid communication with the first valve, wherein the second syringe is in fluid communication with the injecting member when the first valve is in the second position and when the second valve is in the third position.

3. The device of claim 2, wherein the first syringe includes a first barrel having a distal end, an opposing proximal end, and a first tubular tip projecting from the distal end configured to facilitate connection with the first valve, the proximal end being configured to receive a first piston longitudinally slidable within the first barrel,

wherein the second syringe includes a second barrel having a distal end, an opposing proximal end, and a second tubular tip projecting from the distal end configured to facilitate connection with the second valve, the proximal end being configured to receive a second piston longitudinally slidable within the second barrel,

wherein the accumulator includes a third barrel having a distal end, an opposing proximal end, a third tubular tip projecting from the distal end configured to facilitate connection with the second valve, and a third piston longitudinally slidable within the third barrel, the third piston being biased towards the distal end of the third barrel consistent with the empty position.

4. The device of claim 3, wherein manipulation of the second piston towards the distal end of the second barrel withdraws the liquid medication from the first syringe and into the second syringe when the first valve is in the first position and when the second valve is in one of the second position and the third position.

5. The device of claim 3, wherein manipulation of the second piston towards the distal end of the second barrel cooperates with the biased third piston of the accumulator to agitate the liquid medication back and forth between the second syringe and the accumulator when the second valve is in the first position.

6. The device of claim 3, wherein manipulation of the second piston towards the distal end of the second barrel forces the liquid medication from the second syringe to the injecting member for patient delivery when the first valve is in the second position and when the second valve is in the third position.

7. The device of claim 1, wherein first syringe includes a first barrel and a first plunger longitudinally slidable within the first barrel, wherein the second syringe includes a second barrel and a second plunger longitudinally slidable within the second barrel, wherein the accumulator includes a third barrel and a third plunger longitudinally slidable within the third barrel.

8. The device of claim 7, further comprising a handle coupled to the second syringe, the handle being configured to assist an operator to manipulate the second plunger.

9. The device of claim 7, wherein the accumulator is disposed within the first syringe, wherein the first plunger of the first syringe forms the third barrel of the accumulator such that the accumulator is longitudinally slidable within the first syringe.

10. The device of claim 9, further comprising a locking element configured to prevent the accumulator from longitudinally sliding within the first syringe when in a locked position.

11. The device of claim 10, wherein the third barrel of the accumulator includes a threaded outer wall, wherein the locking element includes a threaded member coupled with a cam lever, wherein the threaded member is configured to intersect a portion of the first barrel of the first syringe, wherein the cam lever is configured to selectively engage the threaded member against the threaded outer wall to lock the accumulator in place within the first syringe defining the locked position.

12. The device of claim 10, wherein the valve is selectively adjustable between a first position in which the first syringe and the accumulator are in fluid communication with the second syringe and in which the first syringe, the accumulator, and the second syringe are not in fluid communication with the injecting member, and a second position in which the first syringe and the accumulator are not in fluid communication with the second syringe or the injecting member and in which the second syringe is in fluid communication with the injecting member.

13. The device of claim 12, wherein the first barrel includes a distal end, an opposing proximal end, and a first tubular tip projecting from the distal end configured to facilitate connection with the valve, the proximal end being configured to receive the first plunger, wherein the second barrel includes a distal end, an opposing proximal end, and a second tubular tip projecting from the distal end configured to facilitate connection with the valve, the proximal end being configured to receive the second plunger, wherein the third barrel includes a distal end, an opposing proximal end, and a channel formed through the distal end providing a fluid communication between the first syringe and the accumulator, the proximal end being configured to receive the third plunger, the third plunger being biased towards the distal end of the third barrel consistent with the empty position.

14. The device of claim 13, wherein manipulation of the second plunger towards the proximal end of the second barrel withdraws the liquid medication from the first syringe and into the second syringe when the valve is in the first position and when the locking element is in an unlocked position.

15. The device of claim 13, wherein manipulation of the second plunger towards the distal end of the second barrel forces the liquid medication from the second syringe to the injecting member for patient delivery when the valve is in the second position.

16. The device of claim 13, wherein manipulation of the second plunger towards the distal end of the second barrel cooperates with the biased third plunger and the locking element to agitate the liquid medication back and forth between the second syringe and the accumulator when the valve is in the first position and when the locking element is in the locked position.

17. A syringe device for agitating and delivering a liquid medication to a patient comprising:

an injecting member;

a first syringe configured to provide the liquid medication, the first syringe having a first barrel including a first plunger longitudinally slidable within the first barrel;

a second syringe configured to fluidly communicate with the injecting member and the first syringe, the second syringe being configured to receive the liquid medication from the first syringe and move the liquid medication to the injecting member for patient delivery, the second syringe having a second barrel including a second plunger longitudinally slidable within the second barrel;

an accumulator configured to fluidly communicate with the second syringe, the accumulator including a third barrel having a third plunger longitudinally slidable within the third barrel, the third plunger being biased to an empty position to move the liquid medication to the second syringe, wherein the first plunger of the first syringe forms the third barrel of the accumulator such that the accumulator is longitudinally slidable within the first syringe;

a locking element configured to prevent the accumulator from longitudinally sliding within the first syringe when in a locked position; and

a valve coupling the first syringe to the second syringe, the valve being selectively adjustable between a first position in which the first syringe and the accumulator are in fluid communication with the second syringe and in which the first syringe, the accumulator, and the second syringe are not in fluid communication with the injecting member, and a second position in which the first syringe and the accumulator are not in fluid communication with the second syringe or the injecting member and in which the second syringe is in fluid communication with the injecting member.

18. A method of agitating and delivering a liquid medication to a patient comprising the steps of:

providing a syringe device including;

an injecting member;

a first syringe configured to provide the liquid medication;

a second syringe configured to receive the liquid medication from the first syringe and move the liquid medication to the injecting member for patient delivery, the second syringe also being coupled to the first syringe by a valve, the valve being selectively adjustable between a first position in which the first syringe is in fluid communication with the second syringe and a second position in which the first syringe is not in fluid communication with the second syringe; and

an accumulator configured to receive a portion of the liquid medication and to agitate the liquid medication back and forth between the accumulator and the second syringe, the accumulator being biased to an empty position to move the liquid medication to the second syringe by a biasing member, wherein the biasing member is one of a spring, foam, gas, balloon, elastomer, electromagnetic field, and gravity;

transferring the liquid medication from the first syringe to the second syringe;

shuttling the liquid medication back and forth between the second syringe and the biased accumulator; and

transferring the liquid medication from the second syringe to the injecting member for patient delivery.

19. The method of claim 18, wherein the accumulator is slidably disposed within the first syringe.

20. The method of claim 18, wherein the syringe device further comprises a locking element configured to prevent the accumulator from longitudinally sliding within the first syringe when in a locked position.

21. A syringe device for agitating and delivering a liquid medication to a patient comprising:

an injecting member;

a first syringe configured to provide the liquid medication;

a second syringe in selective fluid communication with the injecting member and the first syringe, the second syringe being configured to receive the liquid medication from the first syringe and move the liquid medication to the injecting member for patient delivery, the second syringe also being coupled to the first syringe by a valve, the valve being selectively adjustable between a first position in which the first syringe is in fluid communication with the second syringe and a second position in which the first syringe is not in fluid communication with the second syringe, the second syringe having a distal end and being coupled to the valve and the first syringe by a tip projecting from the distal end; and

an accumulator in selective fluid communication with the second syringe, the accumulator being biased to an empty position to move the liquid medication to the second syringe, wherein the biased accumulator cooperates with the second syringe to agitate the liquid medication between the second syringe and the accumulator prior to patient delivery.