Spindle and bearing combination and drug delivery device

• US 9,108,007 B2
• Filed: 05/27/2010
• Issued: 08/18/2015
• Est. Priority Date: 06/01/2009
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Plumptre, David Aubrey
• Primary Examiner(s): Price, Nathan R
• Application Number:
  US12/788,755
• Publication Number:
  US 20100331786A1
• Time in Patent Office: 1,909 Days
• Field of Search: 604/134, 604/135, 604/155, 604207-211, 604/224, 604/228, 604/229, 604/220
• US Class Current: 1/1
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31515 Connection of piston with piston rod
• CPC Class Codes: A61M 5/3158 performed by axially moving actuator operated by user, e.g. an injection button
• CPC Class Codes: A61M 5/5066 Means for preventing re-use by disconnection of piston and piston-rod
• CPC Class Codes: A61M 5/5086 for indicating if defective, used, tampered with or unsterile
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

An improved spindle and bearing combination for a drug delivery device is provided that has a first connection between the spindle and bearing comprising a web and a second connection that replaces the first connection when the web is severed that allows the spindle to rotate relative to the bearing.

Claims

1. A spindle and bearing combination for use in a drug delivery device comprising,

a) a rotatable spindle having a distal end;

and

b) a disk-shaped bearing configured to abut a proximal face of a non-rotatable piston in a medicament container, where the disk-shaped bearing has a first connection and a second connection to the distal end of the spindle, where the first connection comprises a web that fixedly attaches the disk-shaped bearing to the spindle to prevent independent movement of the disk-shaped bearing relative to the spindle and where the second connection is created and replaces the first connection when the web is sheared such that the spindle is rotatably connected to the disk-shaped bearing and the distal end of the spindle is retained within the disk-shaped bearing by a pair of cooperating web shears formed from the sheared web.

2. The spindle and bearing combination of claim 1 where the second connection comprises a joint that allows the spindle to rotate relative to the disk-shaped bearing.

3. The spindle and bearing combination of claim 2 where the second connection prevents accidental separation of the disk-shaped bearing from the spindle.

4. The spindle and bearing combination of claim 1 where the spindle has at least one helical groove positioned longitudinally along the spindle.

5. The spindle and bearing combination of claim 1 where the spindle and disk-shaped bearing are assembled as part of an injection device when the first connection remains intact.

6. The spindle and bearing combination of claim 1 where the spindle and disk-shaped bearing are connected with the second connection during delivery of a first dose with an injection device containing the spindle and bearing combination.

7. The spindle and bearing combination of claim 1 where the spindle and disk-shaped bearing are assembled as part of an injection device and the first connection is modified to the second connection during the assembly of the device.

8. A method of fabricating a spindle and bearing combination for a drug delivery device comprising the steps of,

a) providing a unitary part comprising,

i) a rotatable spindle having a distal end and at least one helical groove positioned longitudinally along the spindle;

and

ii) a disk-shaped bearing configured to abut a proximal face of a nonrotatable piston in a medicament container, where the disk-shaped bearing has a first connection comprising a web that fixedly attaches the disk-shaped bearing to the spindle preventing independent movement of the disk-shaped bearing relative to the spindle;

b) assembling the unitary part into a housing of a drug delivery device; and

c) shearing the web, thereby deforming and stretching the web, to form a second connection comprising a joint having a pair of cooperating web shears formed from the sheared web that allows the spindle to rotate relative to the disk-shaped bearing and that retains the distal end of the spindle within the disk-shaped bearing.

9. A method of fabricating a secure connection in a drug delivery device comprising the steps of,

a) providing a unitary part during the assembly of a drug delivery device comprising,

i) a first portion securely connected to a section portion through a breakable and extendable web;

and

b) assembling the unitary part into a housing of the drug delivery device; and

c) shearing the web, thereby deforming and stretching the web, to form a second connection comprising a joint having a pair of cooperating web shears formed from the sheared web that allows the first portion to move relative to the second portion while remaining connected to the second portion and that retains the distal end of the spindle within the second portion.