Methods and systems for dosing control in an automated fluid delivery system
First Claim
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1. A system for dispensing a radiopharmaceutical fluid, comprising:
- a pump configured to force an aliquot of a radiopharmaceutical fluid from a fluid source into a fluid delivery channel;
at least one radioactivity sensor configured to measure a sample value of a radioactivity property of the aliquot;
a processor in communication with the pump and the at least one radioactivity sensor; and
a non-transitory, computer-readable storage medium in operable communication with the processor, wherein the computer-readable storage medium contains one or more programming instructions that, when executed, cause the processor to;
receive the sample value,receive a source value of the radioactivity property for the fluid source,determine a sample volume of the aliquot based on a comparison of the sample value and the source value;
determine a pump coefficient based on a comparison of the sample volume with an expected volume, wherein the pump coefficient is configured to indicate a volume of fluid forced into the fluid delivery channel per unit; and
control operation of the pump to dispense a predetermined dose of the radiopharmaceutical fluid based on the comparison of the sample volume with the expected volume.
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Abstract
Methods and systems for dispensing a fluid using an automated fluid delivery system are disclosed. A pump may be configured to force an aliquot of fluid into a fluid delivery channel. A processor may receive values of a property for the aliquot and the source of the aliquot. The processor may use the values to determine the volume of the aliquot. The determined volume is compared by the processor against an expected volume to establish the amount of fluid being pumped by the pump per unit, such as time or revolutions. The processor controls operation of the pump to dispense a predetermined dose based on the amount of fluid being pumped by the pump per unit.
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Citations
19 Claims
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1. A system for dispensing a radiopharmaceutical fluid, comprising:
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a pump configured to force an aliquot of a radiopharmaceutical fluid from a fluid source into a fluid delivery channel; at least one radioactivity sensor configured to measure a sample value of a radioactivity property of the aliquot; a processor in communication with the pump and the at least one radioactivity sensor; and a non-transitory, computer-readable storage medium in operable communication with the processor, wherein the computer-readable storage medium contains one or more programming instructions that, when executed, cause the processor to; receive the sample value, receive a source value of the radioactivity property for the fluid source, determine a sample volume of the aliquot based on a comparison of the sample value and the source value; determine a pump coefficient based on a comparison of the sample volume with an expected volume, wherein the pump coefficient is configured to indicate a volume of fluid forced into the fluid delivery channel per unit; and control operation of the pump to dispense a predetermined dose of the radiopharmaceutical fluid based on the comparison of the sample volume with the expected volume. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of dispensing a radiopharmaceutical fluid, comprising:
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providing a pump configured to force an aliquot of a radiopharmaceutical fluid from a fluid source into a fluid delivery channel; receiving, by a processor, a source value of a radioactivity property for the fluid source and a sample value of the radioactivity property for the aliquot measured by at least one radioactivity sensor; determining, by the processor, a sample volume of the aliquot based on a comparison of the sample value of the radioactivity property and the source value of the radioactivity property; determining, by the processor, a pump coefficient based on a comparison of the sample volume with an expected volume, wherein the pump coefficient is configured to indicate a volume of fluid forced into the fluid delivery channel per unit; and controlling, by the processor, operation of the pump to dispense a predetermined dose of the radiopharmaceutical fluid based on the comparison of the sample volume with the expected volume. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19)
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Specification