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Implantable device for evaluating autonomic cardiovascular drive in a patient suffering from chronic cardiac dysfunction

  • US 9,114,262 B2
  • Filed: 11/13/2014
  • Issued: 08/25/2015
  • Est. Priority Date: 12/07/2011
  • Status: Active Grant
First Claim
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1. A vagus nerve neurostimulator for modulating autonomic cardiovascular drive, comprising:

  • a pulse generator, wherein the pulse generator generates a pulsed electrical signal comprising;

    a signal ON time;

    a signal OFF time;

    an output current;

    a signal frequency of approximately 10 Hz;

    a pulse width; and

    a duty cycle defined by dividing the signal ON time by the sum of the signal ON time and signal OFF time;

    a therapy lead; and

    an electrode communicatively coupled to the pulse generator via the therapy lead, wherein the electrical signal is applied to a vagus nerve via the electrode to propagate action potentials in both afferent and efferent directions along the vagus nerve at an intensity that avoids acute physiological side effects.

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