System and method for treating ischemic stroke

• US 9,119,656 B2
• Filed: 05/07/2013
• Issued: 09/01/2015
• Est. Priority Date: 09/10/2004
• Status: Active Grant

• Current Assignee: Penumbra, Inc.
• Original Assignee: Penumbra, Inc.
• Inventors: Bose, Arani, Gupta, Vikas, Donahue, Sean, Hui, Delilah
• Primary Examiner(s): Shi, Katherine M
• Assistant Examiner(s): BACHMAN, LINDSEY MICHELE
• Application Number:
  US13/889,201
• Publication Number:
  US 20140155931A1
• Time in Patent Office: 847 Days
• Field of Search: 606/113, 606/114, 606/127, 606/128, 606/159, 606/191, 606/200
• US Class Current: 1/1
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22044 with a pointed tip
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector

Abstract

A thromboembolic removal system for treating ischemic stroke, including a guide and occlusion catheter, a delivery and aspiration catheter, an aspiration pump, a thromboembolic receiver, and a thromboembolic separator.

Claims

1. A method for removing a thromboembolism from a blood vessel, said method comprising:

providing a device comprising a catheter having an axial lumen, a pusher element slidably disposed in the lumen of the catheter, and a thromboembolic receiver on a distal end of the pusher element, the receiver formed of a plurality of structural members arranged to form a sleeve having a central lumen, a first plurality of structural members comprising longitudinally extending struts, a second plurality of the structural members comprising v-shaped engaging elements, and a third set of structural members comprising a plurality of axially spaced-apart circumferential rings attached to the longitudinal struts, each of said v-shaped engaging elements being disposed between adjacent ones of the longitudinal struts and including a first leg extending into the central lumen from a first longitudinal strut and a second leg extending into the central lumen from a second, adjacent longitudinal strut, said first and second legs attached to one another within the central lumen to define a plurality of longitudinally oriented apexes extending in to the central lumen, wherein at least a distal row and a proximal row of the v-shaped engaging elements are disposed between a distal circumferential ring and a proximal circumferential ring and each apex is unattached to any other structure within the central lumen;

providing at least one elongate element;

passing the at least one elongate element through the thromboembolic receiver in order to engage one or more of the engaging elements whereby said engaging elements are prevented from extending medially into the lumen of the thromboembolic receiver;

positioning a distal end of the catheter adjacent to the thromboembolism in the blood vessel;

withdrawing said one or more elongate elements until the engaging elements are released from the constraint of the elongate element;

retracting the catheter relative to the pusher element to release the thromboembolic receiver wherein an open end of the expanded cylindrical thromboembolic receiver engages the thromboembolism; and

retracting the pusher element to remove the thromboembolism from the blood vessel.

2. The method according to claim 1, wherein the method also comprises the step of advancing the thromboembolic receiver over the thromboembolism before the step of withdrawing said one or more elongate elements.

3. The method according to claim 1, wherein the method also comprises the additional step of withdrawing the receiver from the blood vessel with the thromboembolism engaged by the thromboembolic receiver.

4. The method according to claim 1, wherein prior to the step of providing a thromboembolic receiver on a distal end of the pusher element that is slidably disposed in the lumen of the catheter, the method also comprises the steps of:

providing the thromboembolic receiver comprising the elements set forth in claim 1;

compressing the thromboembolic receiver to a collapsed configuration; and

positioning the receiver in the collapsed configuration within the catheter.

5. The method according to claim 4, wherein the method further comprises the step of releasing the receiver from the collapsed configuration so that the receiver expands to a cylindrical shape with a fully open end.

6. The method according to claim 1, wherein the step of positioning the catheter within the blood vessel adjacent the thromboembolism further comprises the step of positioning the catheter proximal of the thromboembolism.

7. The method according to claim 1, wherein the method further comprises the step of extending the receiver distally from the catheter.

8. The method according to claim 7, wherein the method further comprises the step of sliding a distal portion of the catheter against a proximal portion of the receiver to cause the receiver to exert pressure against the thromboembolism in a radially inward direction.

9. The method according to claim 1, wherein at least one of the circumferential rings of the thromboembolic receiver further comprises one or more undulations.

10. The method according to claim 1, wherein at least one of the longitudinally extending struts comprises one or more flex regions.

11. The method according to claim 10, wherein the one or more flex regions resemble a letter “

S”

shape.