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Probablistic pharmacokinetic and pharmacodynamic modeling

  • US 9,119,918 B2
  • Filed: 05/08/2013
  • Issued: 09/01/2015
  • Est. Priority Date: 03/25/2009
  • Status: Active Grant
First Claim
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1. A system comprising:

  • a processor; and

    at least one memory, the processor and the at least one memory configured to;

    receive dose event data A;

    receive observations of therapeutic and wellness data Y; and

    determine, based on the received observations of therapeutic and wellness data and the received dose event data, a response H representing a reaction to a substance integrated with an ingestible event marker, according to the following equation;


    Y=AH;

    wherein Y represents a matrix of observations of therapeutic and wellness data, A represents a matrix of dose event data, and H represents a response matrix.

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