Devices and methods for control of blood pressure
First Claim
1. An apparatus for stimulating baroreceptors to treat hypertension of a subject, the apparatus comprising:
- a selective circumferential pressure applicator, comprising;
at least two non-contiguous pressure application surfaces that are configured to increase baroreceptor activity of the subject by applying pressure to an artery of the subject at two or more respective non-contiguous regions around a circumference of the artery at a longitudinal site of the artery, such that between the non-contiguous regions, at the longitudinal site;
there is at least one region of the artery that is more relaxed than in the absence of the apparatus, andthere is at least one region of the artery that is more tense than in the absence of the apparatus; and
a joint configured;
to couple the at least two surfaces to each other on the circumference of the artery at the longitudinal site, andfor at least a portion of a cardiac cycle of the subject, not to contact the artery of the subject on the circumference of the artery at the longitudinal sitewherein the at least two non-contiguous pressure application surfaces and the joint are configured to apply forces passively to the artery during systole and diastole of a cardiac cycle in order to increase the baroreceptor activity and maintain blood flow through the artery.
1 Assignment
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Accused Products
Abstract
Apparatus is provided for reducing hypertension of a subject. A selective circumferential pressure applicator (60) includes at least two surfaces (61) that increase baroreceptor activity of the subject, by applying pressure to an artery (20) of the subject at two or more respective non-contiguous regions around the circumference of the artery, at a longitudinal site of the artery, such that between the non-contiguous regions, at the longitudinal site (a) there is at least one region (22) of the artery that is more relaxed than in the absence of the device, and (b) there is at least one region (21) of the artery that is more tense than in the absence of the device. A joint (63) couples the surfaces to each other. For at least a portion of the subject'"'"'s cardiac cycle, the joint does not to contact the subject'"'"'s artery. Other applications are also provided.
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Citations
20 Claims
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1. An apparatus for stimulating baroreceptors to treat hypertension of a subject, the apparatus comprising:
a selective circumferential pressure applicator, comprising; at least two non-contiguous pressure application surfaces that are configured to increase baroreceptor activity of the subject by applying pressure to an artery of the subject at two or more respective non-contiguous regions around a circumference of the artery at a longitudinal site of the artery, such that between the non-contiguous regions, at the longitudinal site; there is at least one region of the artery that is more relaxed than in the absence of the apparatus, and there is at least one region of the artery that is more tense than in the absence of the apparatus; and a joint configured; to couple the at least two surfaces to each other on the circumference of the artery at the longitudinal site, and for at least a portion of a cardiac cycle of the subject, not to contact the artery of the subject on the circumference of the artery at the longitudinal site wherein the at least two non-contiguous pressure application surfaces and the joint are configured to apply forces passively to the artery during systole and diastole of a cardiac cycle in order to increase the baroreceptor activity and maintain blood flow through the artery. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for stimulating baroreceptors to treat hypertension of a subject, the method comprising:
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using at least two non-contiguous pressure application surfaces that are coupled to each other by a joint, applying pressure to an outer wall of an artery of the subject at two or more respective non-contiguous regions around a circumference of the artery at a longitudinal site of the artery, such that between the non-contiguous regions, at the longitudinal site; there is at least one region of the artery that is more relaxed than in the absence of the at least two non-contiguous pressure application surfaces, and there is at least one region of the artery that is more tense than in the absence of the at least two non-contiguous pressure application surfaces, and placing the joint such that for at least a portion of a cardiac cycle of the subject the joint does not contact the artery of the subject on the circumference of the artery at the longitudinal site wherein the at least two non-contiguous pressure application surfaces and the joint apply forces to the artery passively during systole and diastole of a cardiac cycle in order to stimulate the baroreceptors and maintain blood flow through the artery. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification