Methods and compositions for improving the appearance of skin
First Claim
Patent Images
1. A topical emulsion composition comprising:
- from 0.0001 to 5% at least one Laminaria digitata extract consisting of an aqueous extraction and leaching of lyophilized algae, having a laminarin or mannitol or both laminarin and mannitol content of about 1 to 2% by weight of the total Laminaria digitata composition;
from 0.001 to 5% of at least one Narcissus tazetta extract consisting of a water soluble extract filtrate of Narcissus tazetta bulbs in the dormant state; and
at least one synthetic peptide present in an amount from 0.0001 to 3% and selected from the group consisting of;
Glu-Ile-His-Gly-Ser-Leu-Phe-Lys-NH2 (SEQ ID No;
1),His-Gly-Ser-Leu-Phe-Lys-NH2 (SEQ ID No;
2),Leu-Val-Gly-Ala-Gly-Val-Ser-Ala-NH2 (SEQ ID No;
3),Gly-Ala-Gly-Val-Ser-Ala-Glu (SEQ ID No;
4),Gly-Ala-Gly-Val-Ser-Ala-Glu-NH2 (SEQ ID No;
5),Thr-Gln-Asn-Ile-Asp-Glu-Leu (SEQ ID No;
6),Thr-Gln-Asn-Ile-Asp-Glu-Leu-NH2 (SEQ ID No;
7),Val-Ile-Thr-Gln-Asn-Ile-Asp-Ala-NH2 (SEQ ID No;
8);
and mixtures thereof, with all percentages by weight of the total composition.
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Abstract
A method for stimulating collagen synthesis in aging skin cells in need of treatment by topically applying a composition comprising at least one extract from Laminaria genus, at least one extract from the Narcissus genus, and at least one peptide that stimulates sirtuin 6 activity in the form of a peptide or a yeast extract where the peptide is component of the extract; and a treatment composition comprising at least one extract from Laminaria genus, at least one extract from the Narcissus genus; and at least one peptide that stimulates sirtuin 6 activity.
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Citations
17 Claims
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1. A topical emulsion composition comprising:
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from 0.0001 to 5% at least one Laminaria digitata extract consisting of an aqueous extraction and leaching of lyophilized algae, having a laminarin or mannitol or both laminarin and mannitol content of about 1 to 2% by weight of the total Laminaria digitata composition; from 0.001 to 5% of at least one Narcissus tazetta extract consisting of a water soluble extract filtrate of Narcissus tazetta bulbs in the dormant state; and at least one synthetic peptide present in an amount from 0.0001 to 3% and selected from the group consisting of; Glu-Ile-His-Gly-Ser-Leu-Phe-Lys-NH2 (SEQ ID No;
1),His-Gly-Ser-Leu-Phe-Lys-NH2 (SEQ ID No;
2),Leu-Val-Gly-Ala-Gly-Val-Ser-Ala-NH2 (SEQ ID No;
3),Gly-Ala-Gly-Val-Ser-Ala-Glu (SEQ ID No;
4),Gly-Ala-Gly-Val-Ser-Ala-Glu-NH2 (SEQ ID No;
5),Thr-Gln-Asn-Ile-Asp-Glu-Leu (SEQ ID No;
6),Thr-Gln-Asn-Ile-Asp-Glu-Leu-NH2 (SEQ ID No;
7),Val-Ile-Thr-Gln-Asn-Ile-Asp-Ala-NH2 (SEQ ID No;
8);and mixtures thereof, with all percentages by weight of the total composition. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16, 17)
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11. A topical emulsion composition comprising:
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from 0.0001 to 1% at least one extract of Laminaria digitata consisting of an extract from the aqueous extraction and leaching of lyophilized algae having a laminarin or mannitol or laminarin and mannitol content from about 1 to 2% by weight of the total Laminaria digitata extract; from 0.001 to 1.5% of at least one extract of Narcissus tazetta consisting of a water soluble extract filtrate of Narcissus tazetta bulbs in the dormant state; and at least one synthetic peptide present in an amount from 0.0001 to 1% and selected from the group consisting of; Glu-Ile-His-Gly-Ser-Leu-Phe-Lys-NH2 (SEQ ID No;
1),His-Gly-Ser-Leu-Phe-Lys-NH2 (SEQ ID No;
2),Leu-Val-Gly-Ala-Gly-Val-Ser-Ala-NH2 (SEQ ID No;
3),Gly-Ala-Gly-Val-Ser-Ala-Glu (SEQ ID No;
4),Gly-Ala-Gly-Val-Ser-Ala-Glu-NH2 (SEQ ID No;
5),Thr-Gln-Asn-Ile-Asp-Glu-Leu (SEQ ID No;
6),Thr-Gln-Asn-Ile-Asp-Glu-Leu-NH2 (SEQ ID No;
7),Val-Ile-Thr-Gln-Asn-Ile-Asp-Ala-NH2 (SEQ ID No;
8);and mixtures thereof, with all percentages by weight of the total composition wherein said peptide is in a mixture with yeast extract.
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Specification