Medicament delivery device

• US 9,125,988 B2
• Filed: 04/27/2011
• Issued: 09/08/2015
• Est. Priority Date: 05/07/2010
• Status: Active Grant

• Current Assignee: Shl Medical AG
• Original Assignee: SHL Group AB
• Inventors: Karlsson, Anders
• Primary Examiner(s): Bosques, Edelmira
• Application Number:
  US13/696,368
• Publication Number:
  US 20130053790A1
• Time in Patent Office: 1,595 Days
• Field of Search: 604/218, 604/48, 604/187
• US Class Current: 1/1
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/3247 Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287

Abstract

A medicament delivery device has a housing for a medicament container and a drive unit for a stopper in the container to expel a dose of medicament, the drive unit having a plunger rod and a dual back-to-back force spring assembly connected to the plunger rod; and a lock and release mechanism connected to the drive unit that has a hold member connected to the plunger rod, a rotator member connected to the hold member, and a tubular actuation member linearly slidable in relation to the housing and connected to the rotator member. The hold member is attached to the housing and has a generally tubular lock tube through which the plunger rod extends and two half-cylindrical seats for the dual back-to-back force spring assembly. The lock tube has a resilient lock and release device to interact with both the plunger rod and the rotator member.

Claims

1. A medicament delivery device, comprising:

a housing configured for a medicament container;

a drive unit in the housing and configured for acting on a movable stopper in the medicament container for expelling a dose of medicament, wherein the drive unit includes an elongated plunger rod and a dual back-to-back force spring assembly operatively connected to the plunger rod so as to provide a symmetrical load on the plunger rod; and

a lock and release mechanism operatively connected to the drive unit and configured for releasing the drive unit upon activation, wherein the lock and release mechanism includes a hold member operatively connected to the plunger rod, a rotator member operatively connected to the hold member, and a tubular actuation member linearly slidable in relation to the housing and operatively connected to the rotator member;

wherein the hold member is fixedly attached to the housing and includes a generally tubular lock tube through which the plunger rod extends and two half-cylindrical seats open toward a proximal direction for housing the dual back-to-back force spring assembly;

the lock tube includes a resilient lock and release device configured to interact with both the plunger rod and the rotator member; and

the resilient lock and release device includes two oppositely positioned radial flexible tongues, each with a first radial inwardly directed protrusion and with a first radial outwardly directed protrusion.

2. The medicament delivery device of claim 1, wherein the plunger rod and spring assembly are movable between a loaded state, in which a proximal end of the plunger rod abuts the stopper positioned at a distal end in the medicament container and in which a portion of the strip material is unrolled and extends parallel on each side of the plunger rod, and a relaxed state, in which the plunger rod abuts the stopper positioned at a proximal end in the medicament container and in which the strip material is rolled up.

3. The medicament delivery device of claim 2, wherein the rotator member has an inner circumferential surface having inner ledges and inner grooves and an outer circumferential surface having a number of outer guides in two paths on opposite sides of the rotator member.

4. The medicament delivery device of claim 3, wherein the rotator member rotates between a locked position, in which the first radial outwardly directed protrusions interact with the ledges thereby forcing the radial flexible tongues radially inward such that the first radial inwardly directed protrusions engage into the recesses of the plunger rod for holding the plunger rod and spring assembly in the loaded state, and a released position, in which the first radial outwardly directed protrusions interact with the inner grooves on the inner surface of the rotator member thereby forcing the radial flexible tongues radially outward such that the first radial inwardly directed protrusions disengage from the recesses of the plunger rod for releasing the plunger rod and the spring assembly from the loaded state.

5. The medicament delivery device of claim 4, wherein the tubular actuation member comprises a proximal generally tubular part protruding through the proximal end of the housing, and two longitudinally extending arms;

each longitudinally extending arm comprises a second radial inwardly directly protrusion configured to interact into the paths on the outer surface of the rotator member, such that when proximal generally tubular part is pressed against a drug delivery site, the actuation member is linearly and distally displaced thereby forcing the rotator member to rotate from the locked position to the released position.

6. The medicament delivery device of claim 5, further comprising a security locking member extending through a distal end of the housing and having a proximal end operatively connected to the actuation member, wherein the security locking member is movable between a first position, in which the security locking member is locked to the actuation member for preventing linear and distal displacement of the actuation member when the actuation member is pressed against the drug delivery site, and a second position, in which the security locking member is unlocked from the actuation member for allowing linear and distal displacement of the actuation member when the actuation member is pressed against the drug delivery site.

7. The medicament delivery device of claim 1, wherein the device is a disposable auto-injection device.

8. The medicament delivery device of claim 1, wherein the dual back-to-back force spring assembly includes two springs each of strip material having a front side surface and a back side surface and pre-tensioned into a tightly wound roll with an outer end, each roll is cradled in a corresponding seat of the hold member, and each outer end has its back side surface toward the other outer end and attached to a respective side of a transversal post attached to a distal end of the plunger rod.

9. The medicament delivery device of claim 1, wherein the device is a disposable auto-injection device.

10. A medicament delivery device, comprising:

a housing configured for a medicament container;

a drive unit in the housing and configured for acting on a movable stopper in the medicament container for expelling a dose of medicament, wherein the drive unit includes an elongated plunger rod and a dual back-to-back force spring assembly operatively connected to the plunger rod so as to provide a symmetrical load on the plunger rod; and

a lock and release mechanism operatively connected to the drive unit and configured for releasing the drive unit upon activation, wherein the lock and release mechanism includes a hold member operatively connected to the plunger rod, a rotator member operatively connected to the hold member, and a tubular actuation member linearly slidable in relation to the housing and operatively connected to the rotator member;

wherein the hold member is fixedly attached to the housing and includes a generally tubular lock tube through which the plunger rod extends and two half-cylindrical seats open toward a proximal direction for housing the dual back-to-back force spring assembly;

the lock tube includes a resilient lock and release device configured to interact with both the plunger rod and the rotator member;

the dual back-to-back force spring assembly includes two springs each of strip material having a front side surface and a back side surface and pre-tensioned into a tightly wound roll with an outer end;

each roll is cradled in a corresponding seat of the hold member;

each outer end has its back side surface toward the other outer end and attached to a respective side of a transversal post attached to a distal end of the plunger rod; and

the resilient lock and release device includes two oppositely positioned radial flexible tongues, each with a first radial inwardly directed protrusion and with a first radial outwardly directed protrusion.

11. The medicament delivery device of claim 10, wherein the plunger rod and spring assembly are movable between a loaded state, in which a proximal end of the plunger rod abuts the stopper positioned at a distal end in the medicament container and in which a portion of the strip material is unrolled and extends parallel on each side of the plunger rod, and a relaxed state, in which the plunger rod abuts the stopper positioned at a proximal end in the medicament container and in which the strip material is rolled up.

12. The medicament delivery device of claim 11, wherein the rotator member has an inner circumferential surface having inner ledges and inner grooves and an outer circumferential surface having a number of outer guides in two paths on opposite sides of the rotator member.

13. The medicament delivery device of claim 12, wherein the rotator member rotates between a locked position, in which the first radial outwardly directed protrusions interact with the ledges thereby forcing the radial flexible tongues radially inward such that the first radial inwardly directed protrusions engage into the recesses of the plunger rod for holding the plunger rod and spring assembly in the loaded state, and a released position, in which the first radial outwardly directed protrusions interact with the inner grooves on the inner surface of the rotator member thereby forcing the radial flexible tongues radially outward such that the first radial inwardly directed protrusions disengage from the recesses of the plunger rod for releasing the plunger rod and the spring assembly from the loaded state.

14. The medicament delivery device of claim 13, wherein the tubular actuation member comprises a proximal generally tubular part protruding through the proximal end of the housing, and two longitudinally extending arms;

each longitudinally extending arm comprises a second radial inwardly directly protrusion configured to interact into the paths on the outer surface of the rotator member, such that when proximal generally tubular part is pressed against a drug delivery site, the actuation member is linearly and distally displaced thereby forcing the rotator member to rotate from the locked position to the released position.

15. The medicament delivery device of claim 14, further comprising a security locking member extending through a distal end of the housing and having a proximal end operatively connected to the actuation member, wherein the security locking member is movable between a first position, in which the security locking member is locked to the actuation member for preventing linear and distal displacement of the actuation member when the actuation member is pressed against the drug delivery site, and a second position, in which the security locking member is unlocked from the actuation member for allowing linear and distal displacement of the actuation member when the actuation member is pressed against the drug delivery site.