Inner housing for a drug delivery device

• US 9,125,993 B2
• Filed: 05/28/2010
• Issued: 09/08/2015
• Est. Priority Date: 06/01/2009
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Plumptre, David
• Primary Examiner(s): STIGELL, THEODORE J
• Application Number:
  US13/375,186
• Publication Number:
  US 20120157929A1
• Time in Patent Office: 1,929 Days
• Field of Search: 604/187, 604207-211
• US Class Current: 1/1
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/27 preventing use
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31543 piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button

Abstract

A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.

Claims

1. A dose setting mechanism for a drug delivery device, said mechanism comprising an outer housing, a non-rotating inner housing, a first driver portion, a second driver portion, a spindle axially movable in both a proximal and a distal direction inside and relative to the driver portions, and a dial sleeve disposed between said outer housing and said inner housing, wherein the inner housing has an external groove, said inner housing being rotatably fixed relative to the outer housing and operatively coupled to the second driver portion and guiding said second driver portion to dispense a dose set by said dose setting mechanism and wherein said dial sleeve is rotatably engaged with said external groove of said inner housing such that the dial sleeve translates away from both the inner and outer housing during dose setting;

and with the dose setting mechanism further comprising

a) a first clutch operatively coupled to said dial sleeve and said second driver portion is provided, said first clutch allows said dial sleeve and said second and first driver portions to rotate together during a setting of a dose of said drug delivery device, and said first clutch allows relative rotation of said second and first driver portions and said dial sleeve during an injection of said dose; and

b) a second clutch configured to couple the first and second driver portions to each other during dose setting and to decouple the first and second driver portions when the spindle is moved axially in the proximal direction.

2. The dose setting mechanism of claim 1 wherein a dose dial grip is non-rotatably coupled to a dose button, such that when a dose is set by rotating said dose dial grip of said dose setting mechanism, said dial sleeve is rotated with respect to both said outer housing and said inner housing and said dial sleeve is translated away from both said outer housing and said inner housing while said button does not rotate.

3. The dose setting mechanism of claim 1, wherein said inner housing comprises an internal surface, said internal surface comprising a mechanical configuration that guides said second driver portion to dispense said dose set by said dose setting mechanism.

4. The dose setting mechanism of claim 3 wherein said mechanical configuration of said inner housing comprises a spline that guides said second driver portion to dispense said dose set by said dose setting mechanism.

5. The dose setting mechanism of claim 3 wherein said mechanical configuration of said inner housing comprises a groove that guides said second driver portion to dispense said dose set by said dose setting mechanism.

6. The dose setting mechanism of claim 1 wherein said external groove of said inner housing comprises a helical groove having a constant pitch.

7. The dose setting mechanism of claim 1 wherein said dial sleeve has a generally smooth outer surface.

8. The dose setting mechanism of claim 7 comprising a scale arrangement provided along a portion of said generally smooth outer surface.

9. The dose setting mechanism of claim 8 wherein said scale arrangement provided along said portion of said generally smoother outer surface is viewable only through a window provided in an outer housing of said dose setting mechanism.

10. The dose setting mechanism of claim 1 comprising the spindle operatively coupled to said driver such that when said inner housing guides said second driver to dispense said dose set by said dose setting mechanism, said first driver pushes said spindle to act on a cartridge bung while said spindle translates in a distal direction to expel said dose from said cartridge.

11. The dose setting mechanism of claim 1 wherein the inner surface of said inner housing comprises at least one longitudinal groove.

12. The dose setting mechanism of claim 1 wherein the inner surface of said inner housing comprises at least a portion of a helical groove.

13. The dose setting mechanism of claim 1 wherein the inner surface of said inner housing comprises a male groove guide.

14. The dose setting mechanism of claim 1 wherein said spindle comprises at least one groove, said at least one groove allowing said spindle to translate in a distal direction to expel said dose from a cartridge.

15. The dose setting mechanism of claim 1 wherein the inner housing has a length in its axial direction which is essentially the same as the length of the dose setting mechanism, or the outer housing or the dose dial sleeve.