Anti-cancer compositions and methods
First Claim
1. A method of modulating Akt dysregulation in a cell, comprising:
- contacting the cell with an effective amount of an isoselenocyanate having the structural formula;
R—
(CH2)n—
N═
C═
Se, where n is an integer in the range of 1-8, inclusive, and where R is an aromatic group.
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Accused Products
Abstract
Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.
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Citations
2 Claims
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1. A method of modulating Akt dysregulation in a cell, comprising:
contacting the cell with an effective amount of an isoselenocyanate having the structural formula;
R—
(CH2)n—
N═
C═
Se, where n is an integer in the range of 1-8, inclusive, and where R is an aromatic group.- View Dependent Claims (2)
Specification