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Heparin coatings

  • US 9,127,091 B2
  • Filed: 07/15/2011
  • Issued: 09/08/2015
  • Est. Priority Date: 06/26/2001
  • Status: Active Grant
First Claim
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1. A method of preparing a medical device coating comprising exposing the medical device to a solution comprising a first polymer and a polymeric heat-initiated crosslinker to form a layer on the surface and heating the layer to thereby covalently crosslink the first polymer with the heat-initiated polymeric cross-linker and form the coating on the medical device, wherein the first polymer comprises a copolymer of a heparin macromer, wherein the heparin macromer is selected from the group consisting of a heparin methacrylate, a heparin quaternary ammonium salt complex methacrylate, a heparin methacrylate salt, and a heparin polyethylene glycol methacrylate.

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