Tracking using field mapping

• US 9,131,869 B2
• Filed: 05/11/2010
• Issued: 09/15/2015
• Est. Priority Date: 05/11/2010
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Rhythmia Medical, Inc. (Boston Scientific Corporation)
• Inventors: Harlev, Doron, Kane, Derek, Stewart, Brian, Hultz, Paul, Csendes, Alpar
• Primary Examiner(s): Le, Long V
• Assistant Examiner(s): KELLOGG, MICHAEL S
• Application Number:
  US12/777,397
• Publication Number:
  US 20110282186A1
• Time in Patent Office: 1,953 Days
• Field of Search: 600/407, 600/424, 600/425, 600/427, 600/481, 600/508, 600/509, 600/513
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0044 for the heart
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0536 Impedance imaging, e.g. by tomography
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/061 Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body A61B1/00158 takes precedence
• CPC Class Codes: A61B 5/063 using impedance measurements
• CPC Class Codes: A61B 5/065 Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
• CPC Class Codes: A61B 5/068 using impedance sensors
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/6846 specially adapted to be brought in contact with an internal body part, i.e. invasive
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: A61B 5/6869 Heart

Abstract

Methods and systems for determining the position of an object, such as tracking the position of one or more catheters in a patient'"'"'s heart cavity are disclosed herein.

Claims

1. A method comprising:

causing current to flow among multiple current injecting electrodes, at least some of the current injecting electrodes being placed in stable locations relative to a patient'"'"'s body to generate a field in an organ;

in response to the current flow caused by the current injecting electrodes placed in stable locations relative to the patient'"'"'s body, measuring a signal at each of multiple measuring electrodes on a catheter for each of multiple locations of the catheter to generate information about fields measured at each of the multiple locations;

determining local field maps, wherein each of the local field maps is based on the measured signals for the catheter at a location corresponding to the local field map and characterized by a field function, of potential distribution on a closed surface around the location to points inside the closed surface, that is determined from the measured signals at the location;

subsequent to determining the local field maps, determining a combined model of a field that includes expected signals at additional locations within the organ based on the measured signals by;

reconciling the local field maps to determine relative locations of the local field maps; and

combining the local field maps to generate the combined model of the field; and

subsequent to determining the combined model of the field, determining a position of at least one electrode selected from the group consisting of at least one of the measuring electrodes of the catheter and a measuring electrode of another catheter in the organ based on at least measurements made by the at least one electrode and the combined model of the field that includes the expected signals.

2. The method of claim 1, wherein the current injecting electrodes are not on the catheter that includes the measuring electrodes.

3. The method of claim 1, wherein determining the expected signals comprises determining expected signals in the absence of information from an external tracking system.

4. The method of claim 1, wherein reconciling the local field maps comprises minimizing a cost function on one or more of a point, multiple points, a surface, and a volume.

5. The method of claim 1, wherein reconciling the local field maps to determine the relative locations comprises determining a translation and rotation between the measuring electrodes at the multiple locations.

6. The method of claim 1, wherein the combining comprises aligning information from different local field maps to account for different locations of the catheter based on known relative locations of the measuring electrodes on the catheter.

7. The method of claim 1, wherein determining the expected signals comprises reconciling the local field maps from the multiple locations.

8. The method of claim 7, wherein reconciling the local field maps comprises minimizing a cost function on one or more of a point, a surface, and a volume.

9. The method of claim 7, wherein reconciling the local field maps comprises determining a translation and rotation between the local field maps.

10. The method of claim 1, wherein determining the expected signals comprises determining the expected signals based on the measured signals and known relative locations between the multiple measuring electrodes on the catheter.

11. The method of claim 1, wherein the expected signals comprise a field map.

12. The method of claim 11, wherein the field map comprises a differentiable function.

13. The method of claim 1, wherein determining the expected signals comprises using Laplace'"'"'s equation.

14. The method of claim 1, wherein determining the expected signals comprises using Poisson'"'"'s equation.

15. The method of claim 1, wherein determining the expected signals comprises using a polynomial estimation.

16. The method of claim 1, wherein the current injecting electrodes are mounted on one or more catheters that are secured inside the organ.

17. The method of claim 1, wherein the current injecting electrodes comprise both electrodes mounted on one or more catheters secured inside the organ and one or more body-surface electrodes.

18. The method of claim 1, wherein measuring the signal comprises measuring potentials.

19. The method of claim 1, wherein measuring the signal at the multiple locations comprises moving the catheter to the multiple locations within the organ, and using the measuring electrodes to measure signals for each of the multiple locations of the catheter.

20. The method of claim 1, wherein combining the local field maps comprises sequentially combining the local field maps to generate the combined model of the field.

21. The method of claim 1, wherein combining the local field maps comprises concurrently combining the local field maps to generate the combined model of the field.

22. The method of claim 1, wherein the combined model of the field comprises a weighted mean of the local field maps.

23. The method of claim 1, further comprising:

removing the measuring electrodes from the organ; and

subsequent to removing the measuring electrodes from the organ using the expected signals to track a location of the measuring electrode of the another catheter.

24. The method of claim 1, wherein the current injecting electrodes comprise at least three sets of current injecting electrodes, and wherein the causing of the current flow comprises causing current to flow between each set of current injecting electrodes.

25. The method of claim 1, wherein the organ is the patient'"'"'s heart.

26. The method of claim 1, wherein determining the position comprises determining the position of the measuring electrode of the another catheter with the another catheter being a separate catheter from the catheter that includes the multiple measuring electrodes.

27. The method of claim 1, wherein the measured signals and expected signals are processed to account for respiration and heart beat.

28. The method of claim 27, wherein processing the measured signals and expected signals comprises using information from a catheter electrode positioned in a stable location relative to the organ.

29. The method of claim 28, wherein the stable location comprises the coronary sinus.

30. A method comprising:

causing current to flow among current injecting electrodes that are placed in stable locations relative to a patient'"'"'s body to generate fields in an organ;

measuring signals at measuring electrodes on a catheter for each of multiple locations of the catheter to generate information about the fields at the multiple locations;

generating expected signals at additional locations;

determining local field models, wherein determining a local field model at each location of the multiple locations comprises;

defining a closed surface containing the location;

calculating potential distribution on the closed surface; and

defining a field function from the potential distribution to points inside the closed surface; and

determining a combined field model comprising;

reconciling the local field models at the multiple locations to determine relative locations of the local field models; and

combining the local field models to generate the combined field model.

31. The method of claim 30, comprising:

determining a position of at least one measuring electrode based on one or more measurements made by the at least one measuring electrode and the combined field model.

32. The method of claim 30, wherein reconciling the local field models comprises:

minimizing a cost function on at least one of a point, a surface, and a volume within an intersection of two or more of the local field models.

33. The method of claim 30, wherein combining the local field models to generate the combined field model includes using at least one of a weighted mean of the local field models and a weighted average of the local field models, such that the local field models nearest a given location have the largest impact on the given location.

34. The method of claim 30, wherein combining the local field models to generate the combined field model includes predicting a potential at a given location using the local field models nearest the given location.

35. The method of claim 30, wherein combining the local field models to generate the combined field model includes merging the local field models into a continuous field map on a three dimensional grid of interest.

36. The method of claim 30, wherein reconciling the local field models includes determining a translation and a rotation between two or more of the local field models.

37. The method of claim 30, wherein the combined field model includes a differentiable function.

38. The method of claim 30, wherein the current injecting electrodes are mounted on one or more catheters that are secured inside the organ.

39. The method of claim 30, wherein the current injecting electrodes comprise electrodes mounted on one or more catheters secured inside the organ and one or more body-surface electrodes.

40. The method of claim 30, comprising:

processing the signals to account for respiration and heart beat by normalizing data for field variations due to the cardiac and respiratory cycles.