Valve position sensor

• US 9,132,034 B2
• Filed: 10/01/2012
• Issued: 09/15/2015
• Est. Priority Date: 10/01/2012
• Status: Active Grant

• Current Assignee: Alcon Research, LLC (Alcon Incorporated)
• Original Assignee: Alcon Research Limited (Nestle SA)
• Inventors: Dos Santos, Cesario P.
• Primary Examiner(s): Deak, Leslie
• Assistant Examiner(s): WENG, KAI H
• Application Number:
  US13/632,550
• Publication Number:
  US 20140094736A1
• Time in Patent Office: 1,079 Days
• Field of Search: 604/9, 604/31
• US Class Current: 1/1
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61M 39/227 Valves actuated by a secondary fluid, e.g. hydraulically or pneumatically actuated valves

Abstract

An IOP control device for implantation in an eye of a patient is disclosed, including a housing with an entrance port and an exit port, a membrane anchored within the housing in a manner forming a flow control chamber on a first side of the membrane and a fluid flow passageway on a second opposing side of the membrane, and a position sensor system. The flow control chamber is arranged to contain a gas creating a flow control chamber pressure, and the membrane is configured to affect flow through the fluid flow passageway from the entrance port to the exit port by deflecting in response to changes in the flow control chamber pressure. The position sensor system includes a first conductive portion and a second conductive portion positioned to selectively contact the first conductive portion to indicate the position of the membrane relative to the fluid flow passageway.

Claims

1. An IOP control device for implantation in an eye of a patient, comprising:

a housing sized for implantation into the eye of the patient and including an entrance port and an exit port;

a membrane anchored within the housing in a manner forming a flow control chamber on a first side of the membrane and a fluid flow passageway on a second opposing side of the membrane, the flow control chamber including a flow control chamber pressure and the fluid flow passageway including a fluid flow passageway pressure, the membrane configured to affect flow through the fluid flow passageway from the entrance port to the exit port by deflecting in response to pressure differentials of the flow control chamber pressure and the fluid flow channel pressure acting on the opposing sides of the membrane; and

a position sensor system configured to detect the position of the membrane including;

a first conductive portion positioned on the membrane; and

a second conductive portion positioned on the housing between the entrance port and the exit port, and positioned to selectively contact the first conductive portion to indicate the position of the membrane relative to the fluid flow passageway;

wherein the first and second conductive portions are sized and shaped to form a seal that occludes flow through the fluid flow passageway when the first and second conductive portions are in contact.

2. The IOP control device of claim 1, wherein the first conductive portion is a conductive pad.

3. The IOP control device of claim 2, wherein the second conductive portion is a conductive ring.

4. The IOP control device of claim 2, wherein the conductive pad is positioned on a central portion of the membrane.

5. The IOP control device of claim 2, wherein the conductive pad comprises an integral, raised, central boss portion of the membrane.

6. The IOP control device of claim 2, wherein the conductive pad is fixedly attached to the membrane.

7. The IOP control device of claim 1, wherein the first conductive portion forms a continuous surface of conductive material.

8. The IOP control device of claim 1, wherein the first conductive portion forms a discontinuous surface of conductive material comprising at least a first conductive section and a second conductive section.

9. The IOP control device of claim 1, wherein the first conductive portion includes gold.

10. The IOP control device of claim 1, wherein the second conductive portion forms a continuous annular surface of conductive material.

11. The IOP control device of claim 1, wherein the second conductive portion forms a discontinuous surface of conductive material comprising at least a first conductive section and a second conductive section.

12. The IOP control device of claim 1, wherein the second conductive portion includes gold.

13. The IOP control device of claim 1, wherein the first conductive portion and the second conductive portion are aligned with each other about a central axis of the housing.

14. The IOP control device of claim 1, wherein the position sensor system forms a closed electrical circuit when the first conductive portion contacts the second conductive portion.

15. The IOP control device of claim 8, wherein the position sensor system forms an closed electrical circuit when the second conductive portion contacts and bridges the first conductive section and second conductive section of the first conductive portion.

16. The IOP control device of claim 11, wherein the position sensor system forms an closed electrical circuit when the first conductive portion contacts and bridges the first conductive section and second conductive section of the second conductive portion.

17. The IOP control device of claim 3, wherein the housing further comprises a valve seat circumferentially surrounding the entrance port, and the conductive ring is positioned on the valve seat.

18. The IOP control device of claim 17, wherein the conductive ring comprises an integral, raised, boss portion of the valve seat.

19. The IOP control device of claim 17, wherein the conductive ring is fixedly attached to the valve seat.

20. The IOP control device of claim 3, wherein the conductive pad includes an outer diameter and the conductive ring includes an inner diameter, wherein the outer diameter is greater than the inner diameter.

21. The IOP control device of claim 1, wherein the membrane is shaped and configured as a flexible, corrugated membrane.

22. The IOP control device of claim 1, wherein the flow control chamber is configured to contain a gas creating a flow control chamber pressure, and the flow control chamber includes an actuator fluid and an electrolysis system configured to affect the flow control chamber pressure by generating bubbles by converting at least a portion of the actuator fluid to the gas.

23. The TOP control device of claim 1, wherein the flow control chamber is shaped and configured as a reference pressure chamber having a reference chamber pressure representative of atmospheric pressure.

39. The IOP control device of claim 1, wherein the membrane further comprises first corrugation features proximate to the first conductive portion and second corrugation features spaced from the first corrugation features, wherein depths of the first and second corrugations features are different.

24. An IOP control system for implantation in an eye of a patient, comprising:

a drainage tube configured to convey aqueous humor from an anterior chamber of the eye; and

a flow system in fluid communication with the drainage tube and including;

a housing including a valve seat positioned between an entrance port and an exit port from the drainage tube;

a membrane, the membrane anchored within the housing to form a flow control chamber having a flow control chamber pressure on a first side of the membrane, the implantable device being actuatable in response to a flow control chamber pressure and the membrane being configured to control flow rates of the aqueous humor along the drainage tube by deflecting in response to the flow control chamber pressure; and

a position sensor system including;

a first conductive portion positioned on the membrane; and

a second conductive portion positioned on the valve seat between the entrance port and the exit port;

wherein the first and second conductive portions are sized and shaped to form a seal that occludes flow of the aqueous humor through the drainage tube when the first and second conductive portions are in contact.

25. The IOP control system of claim 24, wherein the first conductive portion and the second conductive portion are aligned with each other about a central axis extending through the valve seat.

26. The IOP control system of claim 24, wherein the first conductive portion is fixedly attached to a central portion of the membrane.

27. The IOP control system of claim 24, wherein the first conductive portion comprises an integral, raised, central boss portion of the membrane.

28. The IOP control system of claim 24, wherein the second conductive portion comprises an integral, raised, boss portion of the valve seat.

29. The IOP control system of claim 28, wherein the second conductive portion is fixedly attached to the valve seat.

30. The IOP control system of claim 24, wherein the first conductive portion comprises a disc including an outer diameter and the second conductive portion comprises a ring including an inner diameter, wherein the outer diameter is greater than the inner diameter.

31. The IOP control system of claim 24, wherein the position sensor system forms a closed electrical circuit when the first conductive portion contacts the second conductive portion.

32. The IOP control system of claim 24, wherein the position sensor system forms an open electrical circuit when the first conductive portion contacts the second conductive portion.

33. A method of regulating drainage from an anterior chamber of an eye with an implantable device, comprising:

directing fluid from an entrance port through a fluid flow passageway formed in part by a flexible membrane, the membrane configured to deflect away from and toward a valve seat to throttle flow by increasing or decreasing the size of the fluid flow passageway;

determining a valve state of the implantable device using a position sensor system configured to detect a position of the membrane relative to the valve seat, wherein determining a valve state comprises detecting a voltage change with a position sensor system, the position sensor system comprising a first conductive portion on the membrane in alignment with a second conductive portion on the valve seat; and

modifying the amount of drainage through the implantable device in response to a flow control pressure acting on the membrane by deflecting the membrane to increase or decrease the size of the fluid flow passageway based on the valve state of the implantable device, wherein deflecting the membrane comprises contacting the first and second conductive portions of the position sensor system to form a seal that occludes flow of the fluid through the fluid flow passageway.

34. The method of claim 33, wherein an electrolysis process using electrodes affects the flow control pressure acting on the membrane.

35. The method of claim 34, wherein modifying the amount of drainage through the implantable device comprises increasing or decreasing power to the electrodes.

36. The method of claim 35, wherein increasing or decreasing power to the electrodes comprises decreasing power to the electrodes when the position sensor system detects that the fluid flow passageway is closed.

37. The method of claim 33, wherein determining a valve state of the implantable device comprises determining whether the valve state of the implantable device is open with fluid flowing from the entrance port into the fluid flow passageway or closed with fluid not flowing from the entrance port into the fluid flow passageway.

38. The method of claim 33, wherein modifying the amount of drainage through the implantable device comprises controlling deflection of the membrane to increase or decrease the size of the fluid flow passageway in response to a closed looped pressure control signal.