In vivo filter assembly

• US 9,132,261 B2
• Filed: 09/21/2011
• Issued: 09/15/2015
• Est. Priority Date: 10/18/2006
• Status: Active Grant

• Current Assignee: Inspired Industry, LLC, InspireMD, Ltd.
• Original Assignee: InspireMD, Ltd.
• Inventors: Holzer, Asher, Bar, Eli, Paz, Ofir
• Primary Examiner(s): BUI, VY Q
• Application Number:
  US13/237,977
• Publication Number:
  US 20120010649A1
• Time in Patent Office: 1,455 Days
• Field of Search: 606/200, 606/191, 606/194, 606/195, 606/198
• US Class Current: 1/1
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61M 2025/1059 having different inflatable sections mainly depending on the response to the inflation pressure, e.g. due to different material properties
• CPC Class Codes: A61M 2025/1081 having sheaths or the like for covering the balloon but not forming a permanent part of the balloon, e.g. retractable, dissolvable or tearable sheaths
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

Disclosed is an assembly for filtering debris flowing in an in vivo fluid stream, the assembly comprising at least one balloon configured to volumetrically expand and, during at least a portion of the expansion, operatively connect with a filter, and to contract following the expansion. The assembly further comprising a filter configured to operatively connect with the at least one balloon during at least a portion of the volumetric expansion of the at least one balloon, such that the filter expands during the operative connection in order to filter debris from a fluid flowing in a fluid stream within which the expanded filter is disposed.

Claims

1. An assembly for filtering debris flowing in an in vivo fluid stream, the assembly comprising:

i) at least one balloon configured to volumetrically expand and, during at least a portion of said expansion, operatively connect with a filter, and to contract following said expansion;

ii) a filter configured to operatively connect with said at least one balloon during at least a portion of said volumetric expansion of said at least one balloon, such that said filter expands during said operative connection in order to filter debris from a fluid flowing in a fluid stream within which said expanded filter is disposed,

wherein said filter includes;

a) a distal portion;

b) a proximal portion;

c) an opening to said filter associated with said proximal portion; and

d) wherein at least one cord guide channel circumferentially encircling at least a portion said proximal portion and comprises two cord channels located substantially on the same cross-sectional plane of the filter, and wherein at least two cords are disposed in each of the cord channels to connect to the filter.

2. The assembly according to claim 1, wherein at least a portion of said filter is configured to removably connect to a luminal aspect associated with said fluid stream, in response to pressure of between at least about one atmosphere and no more than about 20 atmospheres.

3. The assembly according to claim 1, wherein at least a portion of said filter is configured to remain removably connected to a luminal aspect during said contraction of said at least one balloon.

4. The assembly according to claim 3, including at least one cord passing through said at least one cord guide channel and operatively associated with said filter and configured to disconnect at least a portion of said filter from said luminal aspect when tension is applied to said at least one cord.

5. The assembly according to claim 4, wherein said at least a portion of said filter is configured to disconnect from said luminal aspect in response to tension applied to said at least one cord of at least about one Newton.

6. The assembly according to claim 4 wherein said at least a portion of said filter is configured to disconnect from said luminal aspect in response to tension applied to said at least one cord of no more than about 20 Newtons.

7. The assembly according to claim 4, wherein:

i) said at least one balloon comprises an outer wall having a distal end and a proximal end and an inner wall defining a lumen, said lumen extending from said distal end to said proximal end; and

ii) at least a portion of said at least one cord is configured to slidingly pass through said lumen.

8. The assembly according to claim 7, including a catheter having a distal end and a proximal end and a lumen extending from said distal end to said proximal end, wherein said at least one balloon proximal end is operatively associated with said distal end of said catheter.

9. The assembly according to claim 8, wherein said at least one balloon lumen is substantially continuous with said catheter lumen.

10. The assembly according to claim 8, wherein at least a portion of said at least one cord additionally extends through said catheter lumen.

11. The assembly according to claim 3, including a compression sleeve comprising a substantially curved wall having a proximal end, a distal end and a lumen extending from said proximal end to said distal end, said lumen having a cross sectional diameter that is substantially smaller than the maximal cross sectional diameter of said luminal aspect.

12. The assembly according to claim 11, including at least one cord passing through said at least one cord guide channel and operatively associated with said filter, at least a portion of said at least one cord movingly juxtaposed within said compression sleeve lumen.

13. The assembly according to claim 12 wherein when said at least one cord operatively associated with said filter is held relatively stationary during a first distal moving of said compression sleeve, said filter is caused to disconnect from said luminal aspect.

14. The assembly according to claim 12, wherein in response to at least one second distal moving of said sleeve while said at least one cord is held relatively stationary, said filter is caused to radially contract such that a maximal cross sectional diameter of said filter is smaller than a cross sectional diameter of said sleeve lumen.

15. The assembly according to claim 14, wherein in response to at least one third distal moving of said sleeve while said at least one cord is held stationary, at least a portion of said filter is caused to enter said sleeve lumen.

16. The assembly according to claim 1, wherein at least a portion of said filter includes a pressure-sensitive adhesive having an affinity for a tissue associated with an in vivo luminal aspect.

17. The assembly according to claim 1, wherein said filter comprises a flexible sheet material and said guide channel is formed from at least one of:

a bending of a portion of said sheet material; and

a shaped component attached to said sheet material.

18. The assembly according to claim 1, including at least one cord, at least a portion of said at least one cord passes through said guide channel, such that at least a portion of said opening is configured to contract radially inwardly in response to tension applied to said at least one cord.

19. The assembly according to claim 18, wherein said at least one cord channel comprises at least two cord channels and said at least one cord comprises at least two cords, said at least two cord channels being located substantially on the same cross sectional plane of said filter.

20. An assembly for filtering debris flowing in an in vivo fluid stream, the assembly comprising:

i) at least one balloon configured to volumetrically expand and to contract following said expansion; and

ii) a filter comprising a material having tissue connective properties for a portion of luminal tissue associated with an in vivo fluid stream, said filter positioned to operatively connect with said at least one balloon during at least a portion of said expansion and removably connect to least a portion of said tissue and remain so connected during said contraction of said at least one balloon,

wherein said filter includes;

a) a distal portion;

b) a proximal portion;

c) an opening to said filter associated with said proximal portion; and

d) wherein at least one cord guide channel circumferentially encircling at least a portion said proximal portion and comprises two cord channels located substantially on the same cross-sectional plane of the filter, and wherein at least two cords are disposed in each of the cord channels to connect to the filter.