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Determining onsets and offsets of cardiac depolarization and repolarization waves

  • US 9,132,274 B2
  • Filed: 07/26/2013
  • Issued: 09/15/2015
  • Est. Priority Date: 07/26/2013
  • Status: Active Grant
First Claim
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1. A method for selecting an implant site for a pacing lead comprising:

  • a) determining a baseline rhythm using a plurality of body-surface electrodes, the baseline rhythm includes an atrial marker and a ventricular marker (Vs);

    b) defining a pre-specified window between the atrial marker and the ventricular marker;

    c) applying a low pass filter to a signal within the window;

    d) determining a rectified slope of the signal;

    e) determining a time point (t1) in which the rectified slope exceeds 10% of a maximum value of the rectified slope;

    f) determining a point of onset of a depolarization complex in the signal, wherein the point of onset occurs at a largest curvature in the signal within the pre-specified window from Vs-100 ms to t1;

    g) determine an electromechanical delay for each of a plurality of candidate cardiac pacing lead sites using the determined point of onset of the depolarization complex; and

    h) select the implant site for the pacing lead for delivering cardiac pacing based upon the determined electromechanical delays.

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