Methods of use of cyclopamine analogs
First Claim
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1. A method for treating a hyperproliferative disorder, the method comprising administering to a subject an effective amount of a compound having the formula:
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Abstract
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
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Citations
30 Claims
- 1. A method for treating a hyperproliferative disorder, the method comprising administering to a subject an effective amount of a compound having the formula:
- 5. A method of treating a condition mediated by the hedgehog pathway, the method comprising administering to a subject an effective amount of a compound having the formula:
- 15. A method of antagonizing the hedgehog pathway in a subject, the method comprising administering to the subject an effective amount of a compound having the formula:
- 20. A method of antagonizing the hedgehog pathway in a subject, the method comprising administering to the subject an effective amount of a compound having following structure:
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