Methods and systems for determining an algorithm setting based on a difference signal

• US 9,149,196 B2
• Filed: 09/11/2012
• Issued: 10/06/2015
• Est. Priority Date: 09/11/2012
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Rodriguez-Llorente, Fernando, Engelbrecht, Pirow, Wooder, Nicholas James
• Primary Examiner(s): ZEMAN, MARY K
• Application Number:
  US13/609,534
• Publication Number:
  US 20140073872A1
• Time in Patent Office: 1,120 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7235 Details of waveform analysis A61B5/349 takes precedence
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00

Abstract

A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may generate a difference signal based on the physiological signal. The system may determine positive areas associated with positive regions of the difference signal and negative areas associated with negative regions of the difference signal. The system may determine area ratios based on adjacent positive and negative regions of the difference signal. The system may determine an algorithm setting based on the area ratios. The algorithm setting may, for example, affect the amount of filtering applied to the physiological signal.

Claims

1. A subject monitoring pulse oximetry system for determining physiological information of a subject, comprising:

a pulse oximetry sensor configured to detect light attenuated by the subject and generate a photoplethysmographic (PPG) signal based on the detected attenuated light; and

a pulse oximeter coupled to the pulse oximetry sensor, wherein the pulse oximeter is configured to;

store a rate algorithm;

generate a difference signal based on the PPG signal;

determine a plurality of positive areas associated with positive regions of the difference signal;

determine a plurality of negative areas associated with negative regions of the difference signal;

determine a plurality of area ratios based on adjacent positive and negative regions of the difference signal;

determine an algorithm setting based on the plurality of area ratios;

apply the algorithm setting to the rate algorithm stored by the pulse oximeter; and

determine the physiological information of the subject using the rate algorithm and the PPG signal, wherein the physiological information comprises a pulse rate of the subject.

2. The system of claim 1, wherein the pulse oximeter is further configured to sort the plurality of area ratios.

3. The system of claim 2, wherein the pulse oximeter is further configured to identify one of the plurality of area ratios based on the sorting.

4. The system of claim 3, wherein the pulse oximeter is further configured to determine the algorithm setting based on the identified area ratio.

5. The system of claim 3, wherein the pulse oximeter is further configured to normalize the area ratios, wherein the identified area ratio is approximately the twenty-fifth percentile normalized area ratio.

6. The system of claim 1, wherein the algorithm setting affects the amount of filtering applied to the PPG signal.

7. A processing module of a pulse oximeter that is configured to store a rate algorithm for determining physiological information of a subject, wherein the processing module comprises non-transitory computer readable media configured to store instructions that instruct the processing module to:

receive a photoplethysmographic (PPG) signal derived from a detector output of a pulse oximetry sensor, wherein the pulse oximetry sensor is configured to detect light attenuated by the subject and generate the PPG signal based on the detected attenuated light;

generate a difference signal based on the PPG signal;

determine a plurality of positive areas associated with positive regions of the difference signal;

determine a plurality of negative areas associated with negative regions of the difference signal;

determine a plurality of area ratios based on adjacent positive and negative regions of the difference signal;

determine an algorithm setting based on the plurality of area ratios; and

apply the algorithm setting to the rate algorithm stored by the pulse oximeter, wherein the pulse oximeter is configured to determine the physiological information of the subject using the rate algorithm and the PPG signal, wherein the physiological information comprises a pulse rate of the subject.

8. The processing module of claim 7, further configured to sort the plurality of area ratios.

9. The processing module of claim 8, further configured to identify one of the plurality of area ratios based on the sorting.

10. The processing module of claim 9, further configured to determine the algorithm setting based on the identified area ratio.

11. The processing module of claim 9, further configured to normalize the area ratios, wherein the identified area ratio is approximately the twenty-fifth percentile normalized area ratio.

12. The processing module of claim 7, wherein the algorithm setting affects the amount of filtering applied to the PPG signal.

13. A method for determining physiological information of a subject by a pulse oximeter, comprising:

storing, using the pulse oximeter, a rate algorithm;

receiving, using the pulse oximeter, a photoplethysmographic (PPG) signal derived from a detector output of a pulse oximetry sensor, wherein the pulse oximetry sensor is configured to detect light attenuated by the subject and generate the PPG signal based on the detected attenuated light, and wherein the pulse oximeter comprises at least one processor and at least on non-transitory memory configured to store instructions that instruct the at least one processor to execute steps of the method;

generating, using the pulse oximeter, a difference signal based on the PPG signal;

determining, using the pulse oximeter, a plurality of positive areas associated with positive regions of the difference signal;

determining, using the pulse oximeter, a plurality of negative areas associated with negative regions of the difference signal;

determining, using the pulse oximeter, a plurality of area ratios based on adjacent positive and negative regions of the difference signal;

determining, using the pulse oximeter, an algorithm setting based on the plurality of area ratios;

applying, using the pulse oximeter, the algorithm setting to the rate algorithm stored by the pulse oximeter;

determining, using the pulse oximeter, the physiological information of the subject using the rate algorithm and the PPG signal, wherein the physiological information comprises a pulse rate of the subject.

14. The method of claim 13, further comprising sorting, using the pulse oximeter, the plurality of area ratios.

15. The method of claim 14, further comprising identifying, using the pulse oximeter, one of the plurality of area ratios based on the sorting.

16. The method of claim 15, wherein determining the algorithm setting based on the plurality of area ratios comprises determining the algorithm setting based on the identified area ratio.

17. The method of claim 15, further comprising normalizing, using the pulse oximeter, the area ratios, wherein the identified area ratio is approximately the twenty-fifth percentile normalized area ratio.

18. The method of claim 13, wherein the algorithm setting affects the amount of filtering applied to the PPG signal.

19. A non-transitory computer-readable medium for use in determining physiological information of a subject, the non-transitory computer-readable medium comprising:

computer program instructions recorded thereon for causing a pulse oximeter storing a rate algorithm to;

receive a photoplethysmographic (PPG) signal derived from a detector output of a pulse oximetry sensor, wherein the pulse oximetry sensor is configured to detect light attenuated by the subject and generates the PPG signal based on the detected attenuated light;

generate a difference signal based on the PPG signal;

determine a plurality of positive areas associated with positive regions of the difference signal;

determine a plurality of negative areas associated with negative regions of the difference signal;

determine a plurality of area ratios based on adjacent positive and negative regions of the difference signal;

determine an algorithm setting based on the plurality of area ratios

apply the algorithm setting to the rate algorithm stored by the pulse oximeter; and

determine the physiological information of the subject using the rate algorithm and the PPG signal, wherein the physiological information comprises a pulse rate of the subject.

20. The non-transitory computer-readable medium of claim 19, further comprising computer program instructions recorded thereon for causing a pulse oximeter to sort the plurality of area ratios.

21. The non-transitory computer-readable medium of claim 20, further comprising computer program instructions recorded thereon for causing a pulse oximeter to identify one of the plurality of area ratios based on the sorting.

22. The non-transitory computer-readable medium of claim 21, further comprising computer program instructions recorded thereon for causing a pulse oximeter to determine the algorithm setting based on the identified area ratio.

23. The non-transitory computer-readable medium of claim 21, further comprising computer program instructions recorded thereon for causing a pulse oximeter to normalize the area ratios, wherein the identified area ratio is approximately the twenty-fifth percentile normalized area ratio.

24. The non-transitory computer-readable medium of claim 19, wherein the algorithm setting affects the amount of filtering applied to the PPG signal.