Methods and systems for qualifying calculated values based on state transitions

• US 9,149,232 B2
• Filed: 09/11/2012
• Issued: 10/06/2015
• Est. Priority Date: 09/11/2012
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Rodriguez-Llorente, Fernando, Engelbrecht, Pirow, Wooder, Nicholas James
• Primary Examiner(s): Cattungal, Sanjay
• Assistant Examiner(s): Negarestan, Farshad
• Application Number:
  US13/609,462
• Publication Number:
  US 20140073941A1
• Time in Patent Office: 1,120 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02444 Details of sensor A61B5/02427 takes precedence
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients

Abstract

A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may receive a calculated value indicative of a physiological rate. Based on the value, the system may select pairs of values of the physiological signal that are particularly spaced. The system may determine a state for each pair of values. The state may correspond to a set of criteria such as, for example, equalities, inequalities, logical operators, or other criteria. The system may determine a number of state transitions based on the determined states, and qualify or disqualify the calculated value based on the number of state transitions.

Claims

1. A subject monitoring pulse oximetry system for processing physiological information of a subject, comprising:

a pulse oximetry sensor configured to generate a physiological signal, wherein the sensor detects light attenuated by the subject; and

a pulse oximeter coupled to the sensor, wherein the pulse oximeter is configured to;

receive a calculated value that is a candidate for being indicative of a physiological rate of the subject;

select a plurality of pairs of sample points of the physiological signal spaced by a particular spacing, wherein the particular spacing is based on the calculated value;

determine a state for each of the plurality of pairs, wherein each state corresponds to a set of criteria;

determine a number of state transitions based on the determined states;

qualify or disqualify the calculated value as being indicative of the physiological rate of the subject based on the number of state transitions;

determine the physiological rate of the subject based on the calculated value if the calculated value is qualified; and

display the physiological rate of the subject on a display.

2. The system of claim 1, wherein the set of criteria comprises:

a relative magnitude of sample points in a pair to each other;

a relative magnitude of a sample point to a product of the other sample point in a pair and a coefficient; and

a sign of each sample point in a pair.

3. The system of claim 1, wherein the pulse oximeter is further configured to compare the number of state transitions to at least one threshold.

4. The system of claim 3, wherein the at least one threshold comprises an upper threshold and a lower threshold.

5. The system of claim 1, wherein the pulse oximeter is further configured to determine the state from a number of states equal to a power of two, and wherein the power is greater than or equal to 2.

6. The system of claim 1, wherein the calculated value is indicative of a period associated with the physiological rate and wherein the particular spacing is substantially one quarter of the calculated value.

7. The system of claim 1, wherein the pulse oximeter is configured to determine the number of state transitions by calculating a value indicative of the number of state transitions.

8. The system of claim 7, wherein the pulse oximeter is configured to qualify or disqualify the calculated value based on a comparison between the value indicative of the number of state transitions and at least one threshold.

9. A processing module of a pulse oximeter for processing physiological information of a subject, wherein the processing module is configured to:

receive a physiological signal derived from a detector output of a pulse oximetry sensor, wherein the detector detects light attenuated by the subject;

receive a calculated value that is a candidate for being indicative of a physiological rate of the subject;

select a plurality of pairs of sample points of the physiological signal spaced by a particular spacing, wherein the particular spacing is based on the calculated value;

determine a state for each of the plurality of pairs, wherein each state corresponds to a set of criteria;

determine a number of state transitions based on the determined states;

qualify or disqualify the calculated value as being indicative of the physiological rate of the subject based on the number of state transitions;

determine the physiological rate of the subject based on the calculated value if the calculated value is qualified; and

display, on a display of the pulse oximeter, the physiological rate of the subject.

10. The processing module of claim 9, wherein the set of criteria comprises:

a relative magnitude of sample points in a pair to each other;

a relative magnitude of a sample point to a product of the other sample point in a pair and a coefficient; and

a sign of each sample point in a pair.

11. The processing module of claim 9, further configured to compare the number of state transitions to at least one threshold.

12. The processing module of claim 11, wherein the at least one threshold comprises an upper threshold and a lower threshold.

13. The processing module of claim 9, further configured to determine the state from a number of states equal to a power of two, and wherein the power is greater than or equal to 2.

14. The processing module of claim 9, wherein the calculated value is indicative of a period associated with the physiological rate and wherein the particular spacing is substantially one quarter of the calculated value.

15. A method for processing physiological information of a subject by a pulse oximeter, comprising:

receiving, using the pulse oximeter, a physiological signal derived from a detector output of a pulse oximetry sensor, wherein the detector detects light attenuated by the subject;

receiving, using the pulse oximeter, a calculated value that is a candidate for being indicative of a physiological rate of the subject;

selecting, using the pulse oximeter, a plurality of pairs of sample points of the physiological signal spaced by a particular spacing, wherein the particular spacing is based on the calculated value;

determining, using the pulse oximeter, a state for each of the plurality of pairs, wherein each state corresponds to a set of criteria;

determining, using the pulse oximeter, a number of state transitions based on the determined states;

qualifying or disqualifying, using the pulse oximeter, the calculated value as being indicative of the physiological rate of the subject based on the number of state transitions;

determining, using the pulse oximeter, the physiological rate of the subject based on the calculated value if the calculated value is qualified; and

displaying, on a display of the pulse oximeter, the physiological rate of the subject.

16. The method of claim 15, wherein the set of criteria comprises:

a relative magnitude of sample points in a pair to each other;

a relative magnitude of a sample point to a product of the other sample point in a pair and a coefficient; and

a sign of each sample point in a pair.

17. The method of claim 15, wherein qualifying or disqualifying the value as being indicative of the physiological rate comprises comparing the number of state transitions to at least one threshold.

18. The method of claim 17, wherein the at least one threshold comprises an upper threshold and a lower threshold.

19. The method of claim 15, wherein determining the state for each of the plurality of pairs comprises determining the state from a number of states equal to a power of two, and wherein the power is greater than or equal to 2.

20. The method of claim 15, wherein the calculated value is indicative of a period associated with the physiological rate and wherein the particular spacing is substantially one quarter of the calculated value.

21. A non-transitory computer-readable medium for use in processing physiological information of a subject, the computer-readable medium comprising:

computer program instructions recorded thereon for causing a pulse oximeter to;

receive a physiological signal derived from a detector output of a pulse oximetry sensor, wherein the detector detects light attenuated by the subject;

receive a calculated value that is a candidate for being indicative of a physiological rate of the subject;

select a plurality of pairs of sample points of the physiological signal spaced by a particular spacing, wherein the particular spacing is based on the calculated value;

determine a state for each of the plurality of pairs, wherein each state corresponds to a set of criteria;

determine a number of state transitions based on the determined states;

qualify or disqualify the calculated value as being indicative of the physiological rate of the subject based on the number of state transitions;

determine the physiological rate of the subject based on the calculated value if the calculated value is qualified; and

display, on a display of the pulse oximeter, the physiological rate of the subject.

22. The non-transitory computer-readable medium of claim 21, wherein the set of criteria comprises:

a relative magnitude of sample points in a pair to each other;

a relative magnitude of a sample point to a product of the other sample point in a pair and a coefficient; and

a sign of each sample point in a pair.

23. The non-transitory computer-readable medium of claim 21, further comprising computer program instructions recorded thereon for causing the pulse oximeter to compare the number of state transitions to at least one threshold.

24. The non-transitory computer-readable medium of claim 23, wherein the at least one threshold comprises an upper threshold and a lower threshold.

25. The non-transitory computer-readable medium of claim 21, further comprising computer program instructions recorded thereon for causing the pulse oximeter to determine the state from a number of states equal to a power of two, and wherein the power is greater than or equal to 2.

26. The non-transitory computer-readable medium of claim 21, wherein the calculated value is indicative of a period associated with the physiological rate and wherein the particular spacing is substantially one quarter of the calculated value.