Method and apparatus for controlling a process of injury therapy

• US 9,149,646 B2
• Filed: 12/22/2009
• Issued: 10/06/2015
• Est. Priority Date: 12/31/2008
• Status: Active Grant

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Keswarpu, Payal, Srinivasan, Balakrishnan, Kudavelly, Srinivas Rao
• Primary Examiner(s): Thomson, William
• Assistant Examiner(s): LIPITZ, JEFFREY BRIAN
• Application Number:
  US13/142,362
• Publication Number:
  US 20120010683A1
• Time in Patent Office: 2,114 Days
• Field of Search: 607 88- 90, 205/781
• US Class Current: 1/1
• CPC Class Codes: A61B 2017/00061 spectrum
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/242 Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
• CPC Class Codes: A61N 2005/0659 infrared
• CPC Class Codes: A61N 5/06 using light

Abstract

A method and apparatus for controlling a process of injury therapy includes monitoring a Nitric Oxide level of the injury, generating a controlling signal by comparing the Nitric oxide level with a predefined threshold, and adjusting a dosage of light for the injury therapy according to the controlling signal.

Claims

1. A method of controlling a light for therapy of an injury of a subject, comprising the acts of:

detecting a meth-hemoglobin level and a oxy-hemoglobin level of the subject at an injury site of the injury of the subject;

after the detecting act, calculating a nitric oxide level according to a ratio between the meth-hemoglobin level and the oxy-hemoglobin level of the subject;

after the calculating act, generating by a processor a controlling signal by comparing the nitric oxide level with a predefined threshold; and

after the generating act, adjusting a dosage of the light provided to the injury site from a light source according to the controlling signal for providing the therapy.

2. The method as claimed in claim 1, wherein the detecting act includes acts of:

detecting a magnetic field formed due to a transition from Fe²⁺ to Fe³⁺;

acquiring an Fe³⁺ level based on the detected magnetic field; and

calculating the meth-hemoglobin level according to the Fe³⁺ level.

3. The method as claimed in claim 1, wherein the detecting act includes acts of:

illuminating a surface near the injury;

obtaining a spectrum of light reflected from the surface;

determining the ratio between the meth-hemoglobin level and the oxy-hemoglobin level according to the spectrum; and

calculating the meth-hemoglobin level based on the ratio between the meth-hemoglobin level and the oxy-hemoglobin level.

4. The method as claimed in claim 1, wherein the detecting act includes acts of:

illuminating a surface near the injury with the light from the light source;

obtaining a wave band of light reflected from the surface;

detecting a current for the light reflected from the surface by converting the light reflected from the surface into current;

determining the ratio between a meth-hemoglobin level and an oxy-hemoglobin level according to the current; and

calculating the meth-hemoglobin level based on the ratio between the meth-hemoglobin level and the oxy-hemoglobin level.

5. The method as claimed in claim 1, wherein the adjusting act increases the dosage of the light if the calculated nitric oxide level is higher than the predefined threshold, and decreases the dosage of the light if the calculated nitric oxide level is lower than the predefined threshold.

6. An apparatus for controlling a light for therapy of an injury of a subject, comprising:

a light source configured to provide a dosage of the light for the therapy at an injury site of the injury;

a monitoring unit configured to detect a meth-hemoglobin level and a oxy-hemoglobin level of the subject at the injury site; and

a processor configured to;

calculate a nitric oxide level according to a ratio between the meth-hemoglobin level and the oxy-hemoglobin level of the subject,

generate a controlling signal by comparing the nitric oxide level with a predefined threshold, and

adjust the dosage of the light for the therapy provided to the injury site from the light source according to the controlling signal for providing the therapy.

7. The apparatus as claimed in claim 6, wherein the monitoring unit is further configured to:

detect a magnetic field formed due to a transition from Fe²⁺ to Fe³⁺, acquire an Fe³⁺ level according to the magnetic field, and calculate the meth-hemoglobin level according to the Fe³⁺ level.

8. The apparatus as claimed in claim 6, wherein monitoring unit is further configured to:

illuminate a surface near the injury with the light from the light source;

obtain a spectrum of light reflected from the surface;

determine the ratio between a meth-hemoglobin level and an oxy-hemoglobin level according to the spectrum; and

calculate the meth-hemoglobin level based on the ratio of the meth-hemoglobin level and the oxy-hemoglobin level.

9. The apparatus as claimed in claim 6, wherein the monitoring unit is further configured to:

illuminate a surface near the injury;

obtain a wave band of light reflected from the surface;

detect a current for the light reflected from the surface by converting the light reflected from the surface into the current;

determine the ratio between the meth-hemoglobin level and the oxy-hemoglobin level according to the current; and

calculate the meth-hemoglobin level based on the ratio between the meth-hemoglobin level and the oxy-hemoglobin level.

10. The apparatus as claimed in claim 6, wherein the processor is further configured to increase the dosage if the nitric oxide level is higher than the predefined threshold, and decrease the dosage if the nitric oxide level is lower than the predefined threshold.

11. An injury therapy device comprising a plurality of light sources configured to emit lights for therapy of an injury of a subject and an apparatus for controlling a dosage of the lights from the light sources, wherein the apparatus comprises:

a monitoring unit configured to indirectly monitor at an injury site a nitric oxide level released from the injury site of the injury; and

a processor configured to;

calculate a nitric oxide level according to a ratio between the meth-hemoglobin level and the oxy-hemoglobin level of the subject,

generate a controlling signal by comparing the nitric oxide level with a predefined threshold, and

adjust the dosage of the light for the therapy of the injury provided from the plurality of light sources according to the controlling signal,

wherein the monitoring unit comprises a plurality of sensors configured to collect information from the injury, the information comprising one of magnetic field information and spectrum information.

12. The injury therapy device as claimed in claim 11, wherein the plurality of sensors are arranged together with the plurality of light sources on a base to collect the information from the injury.

13. The injury therapy device as claimed in claim 12, wherein the sensors are Giant Magneto Resistive sensors.

14. The injury therapy device of claim 11, wherein the monitoring unit indirectly monitors the nitric oxide level by detecting a meth-hemoglobin level and an oxy-hemoglobin level of the subject at the injury site.

15. The injury therapy device of claim 14, wherein the monitoring unit detects the meth-hemoglobin level by detecting a magnetic field formed due to a transition from Fe²⁺ to Fe³⁺, and acquiring an Fe³⁺ level based on the detected magnetic field;

and wherein the processor calculates the meth-hemoglobin level according to the Fe³⁺ level.

16. The injury therapy device of claim 14, wherein the monitoring unit detects the meth-hemoglobin level by obtaining a spectrum of light reflected from a surface near the injury illuminated by the lights from the plurality of light sources, and the wherein the processor determines the ratio between the meth-hemoglobin level and the oxy-hemoglobin level according to the spectrum and calculates the meth-hemoglobin level based on the ratio between the meth-hemoglobin level and the oxy-hemoglobin level.

17. The injury therapy device of claim 14, wherein the monitoring unit detects the meth-hemoglobin level by obtaining a wave band of light reflected from a surface near the injury illuminated by the lights from the plurality of light sources, and the wherein the processor:

detects a current for the light reflected from the surface by converting the light reflected from the surface into the current;

determines the ratio between the meth-hemoglobin level and the oxy-hemoglobin level according to the current; and

calculates the meth-hemoglobin level based on the ratio between the meth-hemoglobin level and the oxy-hemoglobin level.

18. The injury therapy device of claim 11, wherein the processor increases the dosage of the light if the nitric oxide level is higher than a predefined threshold, and decreases the dosage of the light if the nitric oxide level is lower than the predefined threshold.