Devices, systems, and methods for the fabrication of tissue
DCFirst Claim
1. A bioprinter comprising:
- a) one or more printer heads, wherein each printer head comprises a means for receiving and holding at least one cartridge, and wherein each cartridge comprises a deposition orifice and a bio-ink, the bio-ink comprising a solid or semi-solid composition comprising living cells;
b) a means for dispensing the bio-ink of a selected cartridge by application of pressure to extrude the bio-ink of the selected cartridge through the deposition orifice;
c) a means for determining a position of the selected cartridge in space; and
d) a programmable computer processor for regulating the dispensing of the bio-ink communicatively coupled to the means for determining a position of the selected cartridge and the means for dispensing the bio-ink.
1 Assignment
Litigations
1 Petition
Accused Products
Abstract
Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.
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Citations
11 Claims
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1. A bioprinter comprising:
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a) one or more printer heads, wherein each printer head comprises a means for receiving and holding at least one cartridge, and wherein each cartridge comprises a deposition orifice and a bio-ink, the bio-ink comprising a solid or semi-solid composition comprising living cells; b) a means for dispensing the bio-ink of a selected cartridge by application of pressure to extrude the bio-ink of the selected cartridge through the deposition orifice; c) a means for determining a position of the selected cartridge in space; and d) a programmable computer processor for regulating the dispensing of the bio-ink communicatively coupled to the means for determining a position of the selected cartridge and the means for dispensing the bio-ink. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification