Method for detecting cells with elastic cell membranes
First Claim
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1. A method for detecting cells with elastic cell membranes, the method comprising the steps of:
- fixing a plurality of cells to an impedimetric transducer;
applying osmotic stress to the plurality of cells;
waiting for a predetermined time to permit the plurality of cells to change in volume due to the osmotic stress;
detecting the change in volume with the impedimetric transducer and determining cells with elastic cell membranes are present in the plurality of cells.
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Abstract
The subject matter disclosed in this specification pertains to a method for detecting cells with elastic cell membranes. A plurality of cells are fixed to an impedimetric transducer and osmotic stress is applied. Those cells with elastic membranes, including cancer cells, undergo a volume change which is detected by the impedimetric transducer.
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Citations
19 Claims
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1. A method for detecting cells with elastic cell membranes, the method comprising the steps of:
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fixing a plurality of cells to an impedimetric transducer; applying osmotic stress to the plurality of cells; waiting for a predetermined time to permit the plurality of cells to change in volume due to the osmotic stress; detecting the change in volume with the impedimetric transducer and determining cells with elastic cell membranes are present in the plurality of cells. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for detecting cells with elastic cell membranes, the method comprising the steps of:
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fixing a plurality of cells to an impedimetric transducer; applying hyposmotic stress to the plurality of cells; waiting for a predetermined time to permit the plurality of cells to change in volume due to the hyposmotic stress; detecting an increase in volume with the impedimetric transducer and determining cells with elastic cell membranes are present in the plurality of cells; and displaying the degree of increase in volume to a user. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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Specification