Method and system for patient-specific modeling of blood flow
First Claim
1. A system for providing a noninvasively derived fractional flow reserve and a computerized model of a portion of an anatomy of a patient, the system comprising:
- at least one computer system configured to;
create a three-dimensional model representing at least a portion of multiple coronary arteries emanating from the patient'"'"'s aorta, using patient-specific imaging data derived from a noninvasive imaging source;
create a blood flow model representing blood flow through at least a portion of multiple coronary arteries;
create a multi-dimensional model using the three-dimensional model and the blood flow model;
determine a fractional flow reserve value for at least one location of the coronary arteries, using the multi-dimensional model and without using any invasive fractional flow reserve measurement technique; and
display the three-dimensional model and the determined fractional flow reserve value together on a display device.
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Accused Products
Abstract
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient'"'"'s heart, and create a three-dimensional model representing at least a portion of the patient'"'"'s heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient'"'"'s heart and determine a fractional flow reserve within the patient'"'"'s heart based on the three-dimensional model and the physics-based model.
251 Citations
35 Claims
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1. A system for providing a noninvasively derived fractional flow reserve and a computerized model of a portion of an anatomy of a patient, the system comprising:
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at least one computer system configured to; create a three-dimensional model representing at least a portion of multiple coronary arteries emanating from the patient'"'"'s aorta, using patient-specific imaging data derived from a noninvasive imaging source; create a blood flow model representing blood flow through at least a portion of multiple coronary arteries; create a multi-dimensional model using the three-dimensional model and the blood flow model; determine a fractional flow reserve value for at least one location of the coronary arteries, using the multi-dimensional model and without using any invasive fractional flow reserve measurement technique; and display the three-dimensional model and the determined fractional flow reserve value together on a display device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method for providing a noninvasively derived fractional flow reserve value and a computerized model of a portion of an anatomy of a patient using at least one computer system, the method comprising:
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creating, using the at least one computer system, a three-dimensional model representing at least a portion of multiple coronary arteries emanating from the patient'"'"'s aorta, using patient-specific imaging data derived from a noninvasive imaging source; create a blood flow model representing blood flow through at least a portion of multiple coronary arteries; create a multi-dimensional model using the three-dimensional model and the blood flow model; determining, using the at least one computer system, a fractional flow reserve value within at least one of the coronary arteries based on the multi-dimensional model; and displaying the three-dimensional model and the determined fractional flow reserve value together on a display device. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A non-transitory computer readable medium for use on at least one computer system containing computer-executable programming instructions for performing a method for providing a noninvasively derived fractional flow reserve value and a computerized model of a portion of an anatomy of a patient, the method comprising:
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receiving patient-specific imaging data representing at least a portion of multiple coronary arteries emanating from the patient'"'"'s aorta, wherein the data is derived from a noninvasive imaging source; creating, using the at least one computer system, a three-dimensional model representing at least the portion of the patient'"'"'s aorta and the multiple coronary arteries, using the patient-specific imaging data; creating a blood flow model representing blood flow through at least a portion of multiple coronary arteries; create a multi-dimensional model using the three-dimensional model and the blood flow model; determining, using the at least one computer system, at least one fractional flow reserve value for each of the coronary arteries of the multi-dimensional model; and displaying the three-dimensional model and the at least one fractional flow reserve value determined for each of the coronary arteries together on a display device. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35)
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Specification