Methods and systems for determining an algorithm setting based on a difference signal

• US 9,155,478 B2
• Filed: 09/11/2012
• Issued: 10/13/2015
• Est. Priority Date: 09/11/2012
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Rodriguez-Llorente, Fernando, Engelbrecht, Pirow, Wooder, Nicholas James
• Primary Examiner(s): ZEMAN, MARY K
• Application Number:
  US13/609,523
• Publication Number:
  US 20140073871A1
• Time in Patent Office: 1,127 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7235 Details of waveform analysis A61B5/349 takes precedence
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00

Abstract

A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may generate a difference signal based on the physiological signal and sort the difference signal to generate a sorted difference signal. The system may identify a midpoint of a first segment of the difference signal and a midpoint of a second segment of the difference signal. The first segment may correspond to positive values of the difference signal and the second segment may correspond to negative values of the difference signal. The system may determine an algorithm setting based on the first midpoint and the second midpoint. The algorithm setting may, for example, affect the amount of filtering applied to the physiological signal.

Claims

1. A subject monitoring pulse oximetry system for determining physiological information of a subject, comprising:

a pulse oximetry sensor configured to detect light attenuated by the subject and generate a photoplethysmographic (PPG) signal based on the detected attenuated light; and

a pulse oximeter coupled to the pulse oximetry sensor, wherein the pulse oximeter is configured to;

store a rate algorithm;

generate a difference signal based on the PPG signal;

sort the difference signal in an order based on the values of the difference signal to generate a sorted difference signal;

identify a first midpoint of a first segment of the sorted difference signal;

identify a second midpoint of a second segment of the sorted difference signal;

determine an algorithm setting based on the first midpoint and the second midpoint;

apply the algorithm setting to the rate algorithm stored by the pulse oximeter; and

determine the physiological information of the subject using the rate algorithm and the PPG signal, wherein the physiological information comprises pulse rate of the subject.

2. The system of claim 1, wherein the pulse oximeter is further configured to:

determine a first offset associated with the first segment;

determine a second offset associated with the second segment; and

determine the algorithm setting based on the first midpoint, second midpoint, the first offset, and the second offset.

3. The system of claim 1, wherein the pulse oximeter is further configured to:

determine a first offset associated with the first segment;

determine a second offset associated with the second segment;

determine a first difference between the first midpoint and the first offset;

determine a second difference between the second midpoint and the second offset; and

determine the algorithm setting based on the first difference and the second difference.

4. The system of claim 3, wherein the pulse oximeter is further configured to:

determine a ratio based on the first difference and the second difference; and

determine the algorithm setting based on the ratio.

5. The system of claim 1, wherein the first segment comprises positive values and the second segment comprises negative values.

6. The system of claim 1, wherein the algorithm setting affects the amount of filtering applied to the PPG signal.

7. A pulse oximetry processing module for determining physiological information of a subject, wherein the pulse oximetry processing module comprises non-transitory computer-readable storage media configured to:

store a rate algorithm;

receive a photoplethysmographic (PPG) signal from a pulse oximetry sensor, wherein the pulse oximetry sensor detects light attenuated by the subject and generates the PPG signal based on the detected attenuated light;

generate a difference signal based on the PPG signal;

sort the difference signal in an order based on the values of the difference signal to generate a sorted difference signal;

identify a first midpoint of a first segment of the sorted difference signal;

identify a second midpoint of a second segment of the sorted difference signal;

determine an algorithm setting based on the first midpoint and the second midpoint;

apply the algorithm setting to the rate algorithm stored by the pulse oximetry processing module; and

determine the physiological information of the subject using the rate algorithm and the PPG signal, wherein the physiological information comprises pulse rate of the subject.

8. The pulse oximetry processing module of claim 7, wherein the non-transitory computer-readable storage media is further configured to:

determine a first offset associated with the first segment;

determine a second offset associated with the second segment; and

determine the algorithm setting based on the first midpoint, second midpoint, the first offset, and the second offset.

9. The pulse oximetry processing module of claim 7, wherein the non-transitory computer-readable storage media is further configured to:

determine a first offset associated with the first segment;

determine a second offset associated with the second segment;

determine a first difference between the first midpoint and the first offset;

determine a second difference between the second midpoint and the second offset; and

determine the algorithm setting based on the first difference and the second difference.

10. The pulse oximetry processing module of claim 9, wherein the non-transitory computer-readable storage media is further configured to:

determine a ratio based on the first difference and the second difference; and

determine the algorithm setting based on the ratio.

11. The pulse oximetry processing module of claim 7, wherein the first segment comprises positive values and the second segment comprises negative values.

12. The pulse oximetry processing module of claim 7, wherein the algorithm setting affects the amount of filtering applied to the PPG signal.

13. A method for determining physiological information of a subject, comprising:

storing, using a pulse oximeter, a rate algorithm;

receiving, using the pulse oximeter, a photoplethysmographic (PPG) signal derived from a pulse oximetry sensor output, wherein the pulse oximetry sensor detects light attenuated by the subject and generates the PPG signal based on the detected attenuated light;

generating, using the pulse oximeter, a difference signal based on the PPG signal;

sorting, using the pulse oximeter, the difference signal in an order based on the values of the difference signal to generate a sorted difference signal;

identifying, using the pulse oximeter, a first midpoint of a first segment of the sorted difference signal;

identifying, using the pulse oximeter, a second midpoint of a second segment of the sorted difference signal;

determining, using the pulse oximeter, an algorithm setting based on the first midpoint and the second midpoint;

applying, using the pulse oximeter, the algorithm setting to the stored rate algorithm; and

determining, using the pulse oximeter, the physiological information of the subject using the rate algorithm and the PPG signal, wherein the physiological information comprises pulse rate of the subject.

14. The method of claim 13, further comprising:

determining a first offset associated with the first segment; and

determining a second offset associated with the second segment, wherein determining the algorithm setting comprises determining the algorithm setting based on the first midpoint, second midpoint, the first offset, and the second offset.

15. The method of claim 13, further comprising:

determining a first offset associated with the first segment;

determining a second offset associated with the second segment;

determining a first difference between the first midpoint and the first offset; and

determining a second difference between the second midpoint and the second offset, wherein determining the algorithm setting based on the first and second midpoints comprises determining the algorithm setting based on the first difference and the second difference.

16. The method of claim 15, further comprising determining a ratio based on the first difference and the second difference, wherein determining the algorithm setting based on the first difference and the second difference comprises determining the algorithm setting based on the ratio.

17. The method of claim 13, wherein the first segment comprises positive values and the second segment comprises negative values.

18. The method of claim 13, wherein the algorithm setting affects the amount of filtering applied to the PPG signal.

19. A non-transitory computer-readable storage media for use in determining physiological information of a subject, the non-transitory computer-readable storage media having computer program instructions recorded thereon for:

storing a rate algorithm;

receiving a photoplethysmographic (PPG) signal derived from a pulse oximetry sensor output, wherein the pulse oximetry sensor detects light attenuated by the subject and generates the PPG signal based on the detected attenuated light;

generating a difference signal based on the PPG signal;

sorting the difference signal in an order based on the values of the difference signal to generate a sorted difference signal;

identifying a first midpoint of a first segment of the sorted difference signal;

identifying a second midpoint of a second segment of the sorted difference signal;

determining an algorithm setting based on the first midpoint and the second midpoint;

applying the algorithm setting to the stored rate algorithm; and

determining the physiological information of the subject using the rate algorithm and the PPG signal, wherein the physiological information comprises pulse rate of the subject.

20. The non-transitory computer-readable storage media of claim 19, having further computer program instructions recorded thereon for:

determining a first offset associated with the first segment;

determining a second offset associated with the second segment; and

determining the algorithm setting based on the first midpoint, second midpoint, the first offset, and the second offset.

21. The non-transitory computer-readable storage media of claim 19, having further computer program instructions recorded thereon for:

determining a first offset associated with the first segment;

determining a second offset associated with the second segment;

determining a first difference between the first midpoint and the first offset;

determining a second difference between the second midpoint and the second offset; and

determining the algorithm setting based on the first difference and the second difference.

22. The non-transitory computer-readable storage media of claim 21, having further computer program instructions recorded thereon for:

determining a ratio based on the first difference and the second difference; and

determining the algorithm setting based on the ratio.

23. The non-transitory computer-readable storage media of claim 19, wherein the first segment comprises positive values and the second segment comprises negative values.

24. The non-transitory computer-readable storage media of claim 19, wherein the algorithm setting affects the amount of filtering applied to the PPG signal.