Ion source method and apparatus used in conjunction with a charged particle cancer therapy system

• US 9,155,911 B1
• Filed: 03/24/2014
• Issued: 10/13/2015
• Est. Priority Date: 05/22/2008
• Status: Active Grant

• Current Assignee: Andrey Vladimirovich Balakin, Pavel Vladimirovich Balakin
• Original Assignee: Vladimir Balakin
• Inventors: Balakin, Vladimir
• Primary Examiner(s): MASKELL, MICHAEL P
• Application Number:
  US14/223,604
• Publication Number:
  US 20150265854A1
• Time in Patent Office: 568 Days
• Field of Search: 2504921-4923, 313153-162
• US Class Current: 1/1
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1097 Means for immobilizing the patient
• CPC Class Codes: A61N 5/1044 with multiple repetitions of the scanning pattern
• CPC Class Codes: A61N 5/1067 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/107 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/1077 Beam delivery systems
• CPC Class Codes: A61N 5/1081 Rotating beam systems with a specific mechanical construction, e.g. gantries
• CPC Class Codes: A61N 5/1082 having multiple beam rotation axes
• CPC Class Codes: G21K 1/093 by magnetic means
• CPC Class Codes: G21K 5/04 with beam-forming means
• CPC Class Codes: H01J 2237/0815 Methods of ionisation
• CPC Class Codes: H01J 37/141 Electromagnetic lenses
• CPC Class Codes: H05H 2007/007 for focusing the beam to irradiation target
• CPC Class Codes: H05H 2007/082 Ion sources, e.g. ECR, duoplasmatron, PIG, laser sources

Abstract

As part of a charged particle cancer therapy system, a negative ion source is used to generate and accelerate an anion, such a C⁻, and to convert the anion to a cation, such as C⁶⁺, through use of one or more electron extraction subsystems. Initially, an electric field is pulsed across a magnetic field to generate the C⁻ anion. Subsequent to extraction of the C− anion from a plasma region using pulsed electrodes, one or both of a hydrogen gas electron stripping system and a carbon foil electron stripping system converts the carbon anion into the cation. The resultant cation is accelerated in a synchrotron, transported along a beam-line, and targeted to a tumor resulting in ablation of the tumor.

Claims

1. An apparatus, comprising:

a negative ion source, comprising;

a first containment wall, comprising a magnetic substance;

a second containment wall, comprising a magnetic material;

a non-conductive separator, said non-conductive separator separating said first containment wall from said second containment wall, wherein said first containment wall, said second containment wall, and said non-conductive separator substantially enclose a central chamber;

a first interior member comprising a non-magnetic substance extending into the central chamber;

a second interior member comprising a non-magnetic material extending into the central chamber;

means for establishing a magnetic field between said first containment wall and said second containment wall; and

means for establishing an electric field between said first interior member and said second interior member, the electric field about normal to the magnetic field during use.

2. The apparatus of claim 1, said first interior member connected to said first containment wall, said second interior member connected to said second containment wall.

3. The apparatus of claim 2, said first interior member separated from said second containment wall, said second interior member separated from said first containment wall.

4. The apparatus of claim 2, wherein said first interior member occupies a geometric center of the central chamber, said non-conductive separator comprising at least one stainless steel ring.

5. The apparatus of claim 2, further comprising:

an injection port, said injection port comprising an opening from an outside of the central chamber to the central chamber.

6. The apparatus of claim 5, said injection port further comprising:

a switch, said switch configured to be opened for time periods of less than ten microseconds; and

a passageway through said first containment wall and through at least a portion of said first interior member to the central chamber.

7. The apparatus of claim 6, wherein both said first containment wall and said second containment wall comprise a ferromagnetic material.

8. The apparatus of claim 7, wherein said means for establishing the electric field comprises a power supply configured to apply a voltage difference between:

(1) said first interior member comprising said non-magnetic substance and (2) said second interior member comprising said non-magnetic material.

9. The apparatus of claim 7, wherein said means for establishing the magnetic field comprises a first power supply configured to apply a first voltage difference between:

(1) said first containment wall comprising said magnetic substance and (2) said second containment wall comprising said magnetic material.

10. A method, comprising the steps of:

providing a negative ion source, comprising;

a first containment wall, comprising a magnetic substance;

a second containment wall, comprising a magnetic material;

a non-conductive separator, said non-conductive separator separating said first containment wall from said second containment wall, said first containment wall, said second containment wall, and said non-conductive separator substantially enclosing a central chamber;

a first interior member comprising a non-magnetic substance extending into the central chamber;

a second interior member comprising a non-magnetic material extending into the central chamber;

establishing a magnetic field between said first containment wall and said second containment wall; and

establishing an electric field between said first interior member and said second interior member, the electric field about normal to the magnetic field.

11. The method of claim 10, further comprising the step of:

injecting a carbon source into the central chamber through at least a portion of said first interior member.

12. The method of claim 11, further comprising the steps of:

forming a high temperature plasma region in the central chamber; and

converting the carbon source to a carbon anion using the high temperature plasma.

13. The method of claim 11, further comprising the steps of:

creating a magnetron discharge to break the carbon source into at least one of a carbon anion and C⁻

, said magnetron discharge formed by crossing a magnetic field between said first containment wall and said second containment wall with an electric field between said first interior member and said second interior member.

14. The method of claim 13, further comprising the step of:

extracting the C⁻

from the central chamber using;

(1) a first voltage difference between said first containment wall and said second containment wall, wherein said second containment wall comprises a first electrode circumferentially surrounding an exit port of the central chamber and (2) a second voltage difference between a second electrode, positioned circumferentially about a beam path outside of said exit port, and said first electrode.

15. The method of claim 14, further comprising the steps of:

initially stripping electrons from the carbon anion, using hydrogen gas, to form positively charged particles comprising at least one of;

a multiply charged carbon cation, a C³⁺ cation, and a C⁴⁺ cation; and

subsequently extracting electrons from at least one of the multiply charged carbon cation, the C³⁺ cation, and the C⁴⁺ cation to form C⁶⁺ by passing the positively charged particles through a carbon foil.

16. The method of claim 15, further comprising the steps of:

forming a vacuum seal between the carbon foil and a vacuum tube, said vacuum tube circumferentially surrounding at least a portion of a longitudinal axis of the beam path;

maintaining a first pressure on a negative ion source side of said carbon foil; and

maintaining a second pressure on a synchrotron side of said carbon foil, said first pressure at least ten times said second pressure.

17. A method for generating a charged particle beam, comprising the steps of:

injecting gas containing carbon into a chamber, the chamber comprising;

a first containment wall, comprising;

a magnetic substance and a first electrode circumferentially surrounding an exit port from the chamber;

a second containment wall, comprising a magnetic material; and

a non-conductive separator, said non-conductive separator separating said first containment wall from said second containment wall, said first containment wall, said second containment wall, and said non-conductive separator substantially enclosing the chamber;

applying a first high voltage pulse and resulting substantially uniform electric field across the chamber between;

(1) a first interior member comprising a non-magnetic substance extending into the chamber and (2) a second interior member comprising a non-magnetic material extending into the chamber;

crossing the electric field with a substantially uniform magnetic field between said first containment wall and said second containment wall to create a magnetron discharge used to break apart the gas containing carbon to form at least a C⁻

anion; and

extracting the C⁻

anion from the chamber forming the charged particle beam using a potential difference between said first electrode and a second electrode, said second electrode at least partially circumferentially enclosing a portion of a beam path of the C⁻

anion outside of the chamber.

18. The method of claim 17, further comprising the steps of:

connecting said first interior member to said first containment wall, said first interior member physically separated from said second containment wall by said non-conductive separator; and

connecting said second interior member to said second containment wall, said second interior member separated from said first containment wall by said non-conductive separator.

19. The method of claim 18, further comprising the steps of:

stripping electrons from the C⁻

anion using hydrogen gas injected into the charged particle beam to form multiply charged carbon cations; and

stripping electrons from the multiply charged carbon cations by passing the charged particle beam through a carbon foil.

20. The method of claim 19, further comprising the step of:

after said step of stripping electrons from the C⁻

anion and said step of stripping electrons from the multiply charged carbon cations, injecting the charged particle beam into a synchrotron.

21. The method of claim 20, wherein the gas containing carbon comprises at least one of:

at least twenty percent carbon by mass;

methane; and

ethane.