Polynucleotides encoding IL-31 monoclonal antibodies
First Claim
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1. An isolated polynucleotide encoding a monoclonal antibody or antigen-binding fragment thereof that specifically binds to a polypeptide consisting of amino acid residues 27-164 of SEQ ID NO:
- 2, wherein the monoclonal antibody or antigen-binding fragment thereof binds to the same epitope as the antibody produced by the hybridoma having ATCC Patent Deposit Designation PTA-6815 for binding to the polypeptide.
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Abstract
The present invention relates to methods of treating pruritic diseases, including but not limited to Contact dermatitis, Atopic Dermatitis, Drug induced delayed type cutaneous allergic reactions, Toxic epidermal necrolysis, Cutaneous T cell Lymphoma, Bullous pemphigoid, Alopecia wereata, Vitiligo, Acne Rosacea, Prurigo nodularis, Scleroderma, Herpes simplex virus, or combination thereof by administering IL-31 monoclonal antibodies. The invention further provides the hybridomas that generate the monoclonal antibodies.
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9 Claims
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1. An isolated polynucleotide encoding a monoclonal antibody or antigen-binding fragment thereof that specifically binds to a polypeptide consisting of amino acid residues 27-164 of SEQ ID NO:
- 2, wherein the monoclonal antibody or antigen-binding fragment thereof binds to the same epitope as the antibody produced by the hybridoma having ATCC Patent Deposit Designation PTA-6815 for binding to the polypeptide.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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