Optical spectroscopic device for the identification of cervical cancer
First Claim
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1. A medical examination device comprising:
- an illumination source, wherein the illumination source includes a lamp and a mirror rotatable between a first mirror position to a second mirror position, and configured such that whenever the mirror is in the first mirror position the mirror directs a beam of light from the lamp in a first beam direction to radiate a first tissue site and whenever the mirror is in the second mirror position the beam of light is transmitted in a second beam direction;
a non-contacting ocular viewer configured to allow the operator of the examination device to directly visualize the first tissue site from the light emanating from the illuminated first tissue site;
a movable contacting fiber optic probe that is selectably movable to various positions in relation to the ocular viewer and having a distal end that is visible through the ocular viewer when the light is directed in the first beam direction of the probe and including both an excitation fiber optic strand and a reception fiber optic strand, wherein the excitation fiber optic strand is configured to receives the beam of light directed in the second beam direction from the illumination source and transmits the received beam of light to radiate a second tissue at a site in contact with the distal end of the probe, and wherein the collection fiber optic strand is configured to receives the light emanating from the illuminated second tissue site; and
a detector configured to receive the transmitted light emanating from the illuminated second tissue site and provides a spectral analysis of the second tissue site.
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Abstract
A medical examination device used for the detection of pre-cancerous and cancerous tissue has an illumination source, a visualization unit, a contacting optical probe, a detector and a process unit. One embodiment of the apparatus includes both a non-contacting macroscopic viewing device (the visualization unit) for visualizing an interior surface of the cervix, as well as a fiber optic wand (contacting optical probe) for spectrally analyzing a microscopic view of the tissue.
40 Citations
24 Claims
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1. A medical examination device comprising:
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an illumination source, wherein the illumination source includes a lamp and a mirror rotatable between a first mirror position to a second mirror position, and configured such that whenever the mirror is in the first mirror position the mirror directs a beam of light from the lamp in a first beam direction to radiate a first tissue site and whenever the mirror is in the second mirror position the beam of light is transmitted in a second beam direction; a non-contacting ocular viewer configured to allow the operator of the examination device to directly visualize the first tissue site from the light emanating from the illuminated first tissue site; a movable contacting fiber optic probe that is selectably movable to various positions in relation to the ocular viewer and having a distal end that is visible through the ocular viewer when the light is directed in the first beam direction of the probe and including both an excitation fiber optic strand and a reception fiber optic strand, wherein the excitation fiber optic strand is configured to receives the beam of light directed in the second beam direction from the illumination source and transmits the received beam of light to radiate a second tissue at a site in contact with the distal end of the probe, and wherein the collection fiber optic strand is configured to receives the light emanating from the illuminated second tissue site; and a detector configured to receive the transmitted light emanating from the illuminated second tissue site and provides a spectral analysis of the second tissue site. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A medical examination device comprising:
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an illumination source, wherein the illumination source includes a lamp and a plurality of selectably engageable filters for preparing a first selected wavelength band of light for a second selected wavelength band of light from the illumination source; a mirror rotatable between a first mirror position and a second mirror position, and configured such that whenever the mirror is in the first mirror position the first wavelength band of light radiates a first macroscopic tissue site and whenever the mirror is in the second mirror position the second wavelength band of light is transmitted to a fiber optic probe; a non-contacting ocular viewer configured to allow the operator of the examination device to visualize the first macroscopic tissue site from a first emitted light beam emanating from the radiated first tissue site; wherein the fiber optic probe is attached to the examination device at a distance from the ocular viewer with a distal end that is selectably movable to various positions in relation to the ocular viewer wherein movement of the distal end of the probe is visible through the ocular viewer, the probe having a shaft, a handle, and a fiber optic bundle having a plurality of excitation fiber optic strands and a reception fiber optic strand, wherein the excitation fiber optic strands are configured to receive the second wavelength band of light and transmit the second wavelength band of light to radiate a second microscopic tissue site having a tissue surface area less than or equal to a contact area that is in contact with the distal end of the probe, and wherein the collection fiber optic strand is configured to receive a second emitted light beam emanating from the radiated second tissue site; and a detector configured to receives the second emitted light beam and generate a spectral analysis of the second microscopic tissue site. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A medical examination device comprising:
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A lamp and a plurality of sectably engageable filters for preparing a first selected wavelength band of light or a second selected wavelength band of light from a light given off by the lamp; a mirror rotatable between a first mirror position and a second mirror position, and configured such that whenever the mirror is in the first mirror position the first wavelength band of light radiates a first macroscopic tissue site and whenever the mirror is in the second mirror position the second wavelength band of light is transmitted to a fiber optic probe; a beam splitter configured to split a first emitted light beam emanating from the radiated first macroscopic tissue site, wherein a first portion of the first emitted light beam is sent to an ocular viewer that allows an operator of the medical examination device to directly visualize the first macroscopic tissue site and wherein a second portion of the first emitted light beam is sent to a camera for recordation; wherein the fiber optic probe is attached to the examination device at a distance from the ocular viewer with a distal end that is selectably movable to various positions in relation to the ocular viewer wherein movement of the distal end of the probe is visible through the ocular viewer, the fiber optic probe having a plurality of excitation fiber optic strands and a reception fiber optic strand, wherein the excitation fiber optic strands are configured to receive the second wavelength band of light and transmit the second wavelength band of light to radiate the second microscopic tissue site that is within the macroscopic tissue site and in contact with the distal end of the fiber optic probe, and wherein the collection fiber optic strand is configured to receives a second emitted light beam emanating from the radiated second tissue site; and a detector configured to receives the second emitted light beam and generates a spectral analysis of the second microscopic tissue site.
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Specification