Concurrent fat and iron estimation in magnetic resonance signal data
First Claim
1. A computer-implemented method for concurrently estimating an amount of fat and iron in anatomical tissue from magnetic resonance (MR) signal data, the method comprising:
- receiving a test signal representative of the anatomical tissue acquired using a MR pulse sequence type;
generating a repository of reference signal data comprising a plurality of reference signals derived by an MR signal simulation for a plurality of different transverse relaxation rates, a plurality of different fat fractions, and the MR pulse sequence type;
identifying a first reference signal in the plurality of reference signals, the first reference signal providing a best match to the test signal based on one or more matching criteria;
searching the repository to determine a first transverse relaxation rate and a first fat fraction associated with the first reference signal; and
estimating the amount of fat and iron in the anatomical tissue based on the first transverse relaxation rate and the first fat fraction.
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Accused Products
Abstract
A computer-implemented method for concurrently estimating the amount of fat and iron in anatomical tissue from magnetic resonance (MR) signal data includes receiving a test signal representative of the anatomical tissue acquired using a MR pulse sequence type. A repository of reference signal data is generated. The repository comprises a plurality of reference signals derived by an MR signal simulation for a plurality of different transverse relaxation rates, a plurality of different fat fractions, and the MR pulse sequence type. A first reference signal is identified in the plurality of reference signals. The first reference signal provides a best match to the test signal based on one or more matching criteria. The repository is searched to determine a first transverse relaxation rate and a first fat fraction associated with the first reference signal. Then, the amount of fat and iron in the anatomical tissue is estimated based on the first transverse relaxation rate and the first fat fraction.
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Citations
20 Claims
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1. A computer-implemented method for concurrently estimating an amount of fat and iron in anatomical tissue from magnetic resonance (MR) signal data, the method comprising:
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receiving a test signal representative of the anatomical tissue acquired using a MR pulse sequence type; generating a repository of reference signal data comprising a plurality of reference signals derived by an MR signal simulation for a plurality of different transverse relaxation rates, a plurality of different fat fractions, and the MR pulse sequence type; identifying a first reference signal in the plurality of reference signals, the first reference signal providing a best match to the test signal based on one or more matching criteria; searching the repository to determine a first transverse relaxation rate and a first fat fraction associated with the first reference signal; and estimating the amount of fat and iron in the anatomical tissue based on the first transverse relaxation rate and the first fat fraction. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A system for concurrently estimating an amount of fat and iron in anatomical tissue from magnetic resonance (MR) signal data, the system comprising:
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an input processor configured to receive a test signal representative of the anatomical tissue acquired using a MR pulse sequence type; a repository of reference signal data comprising a plurality of reference signals derived by MR signal simulation for a plurality of different transverse relaxation rates, a plurality of different fat fractions, and the MR pulse sequence type; an image data processor configured to; identify a first reference signal in the plurality of reference signals providing a best match to the test signal based on one or more matching criteria, search the repository to determine a first transverse relaxation rate and a first fat fraction associated with the first reference signal, and estimate the amount of fat and iron in the anatomical tissue based on the first transverse relaxation rate and the first fat fraction. - View Dependent Claims (9, 10, 11, 12, 13, 14)
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15. A computer-implemented method for concurrently estimating fat and iron in anatomical tissue using magnetic resonance (MR) signal data, the method comprising:
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receiving, by an image processing computer, MR signal data representative of a portion of patient anatomy; generating, by the image processing computer, a library of reference signal entries, each reference signal entry comprising a reference signal, an associated transverse relaxation value, and an associated fat fraction value; receiving, by the image processing computer, a test signal; for each reference signal entry in the library of reference signal entries, calculating an inner product value of the test signal and the respective reference signal entry'"'"'s corresponding reference signal; identifying, by the image processing computer, a first reference signal entry associated with a maximum inner product value; and estimating, by the image processing computer, a test transverse relaxation rate value and a test fat fraction value based on a first associated transverse relaxation value and a first associated fat fraction value corresponding to the first reference signal entry. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification