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Concurrent fat and iron estimation in magnetic resonance signal data

  • US 9,157,975 B2
  • Filed: 10/24/2013
  • Issued: 10/13/2015
  • Est. Priority Date: 10/24/2012
  • Status: Active Grant
First Claim
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1. A computer-implemented method for concurrently estimating an amount of fat and iron in anatomical tissue from magnetic resonance (MR) signal data, the method comprising:

  • receiving a test signal representative of the anatomical tissue acquired using a MR pulse sequence type;

    generating a repository of reference signal data comprising a plurality of reference signals derived by an MR signal simulation for a plurality of different transverse relaxation rates, a plurality of different fat fractions, and the MR pulse sequence type;

    identifying a first reference signal in the plurality of reference signals, the first reference signal providing a best match to the test signal based on one or more matching criteria;

    searching the repository to determine a first transverse relaxation rate and a first fat fraction associated with the first reference signal; and

    estimating the amount of fat and iron in the anatomical tissue based on the first transverse relaxation rate and the first fat fraction.

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