×

Timed, pulsatile release systems

  • US 9,161,919 B2
  • Filed: 07/19/2011
  • Issued: 10/20/2015
  • Est. Priority Date: 05/02/2005
  • Status: Active Grant
First Claim
Patent Images

1. A pharmaceutical composition comprising one or more populations of timed, pulsatile release beads, wherein at least one population of time-pulsatile release beads comprises:

  • a) a core particle comprising a basic active pharmaceutical ingredient or a pharmaceutically acceptable salt thereof;

    b) an inner barrier coating comprising a water-insoluble polymer that is optionally in combination with a water-soluble/pore-forming polymer; and

    c) an outer lag-time coating comprising a water-insoluble polymer in combination with an enteric polymer;

    wherein the population of timed, pulsatile release beads provides a lag time greater than 6 hours before onset of drug release.

View all claims
  • 8 Assignments
Timeline View
Assignment View
    ×
    ×