Control of neural modulation therapy using cervical impedance
First Claim
1. A method comprising:
- detecting fluctuations in a cervical vessel dimension of a patient, wherein detecting the fluctuations includes measuring a cervical impedance of the patient over time;
determining pulsatile information using the detected fluctuations in the cervical vessel dimension of the patient; and
providing a neural modulation therapy coordination with a characteristic of the pulsatile information.
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Abstract
An implantable apparatus can comprise an electrical test energy delivery circuit configured to provide an electrical test signal to a cervical location in a patient body. A detector circuit can use the electrical test signal to detect cervical impedance and generate a cervical impedance signal representing fluctuations in the detected cervical impedance. The implantable apparatus can comprise a therapy delivery circuit, such as configured to provide electrical neural modulation therapy using a neural modulation timing parameter, and a processor circuit that can be coupled to the electrical test energy delivery circuit, the detector circuit, and the therapy delivery circuit. The processor circuit can be configured to determine a pulsatile signal or pulse pressure signal, such as using the cervical impedance signal, identify a characteristic of the pulsatile signal or pulse pressure signal, and control a neural modulation therapy using the timing parameter and the identified pulse pressure signal characteristic.
37 Citations
20 Claims
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1. A method comprising:
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detecting fluctuations in a cervical vessel dimension of a patient, wherein detecting the fluctuations includes measuring a cervical impedance of the patient over time; determining pulsatile information using the detected fluctuations in the cervical vessel dimension of the patient; and providing a neural modulation therapy coordination with a characteristic of the pulsatile information. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method comprising:
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detecting fluctuations in a cervical vessel dimension of a patient, wherein detecting the fluctuations includes measuring a cervical impedance of the patient over time; determining a pulsatile signal based on the detected fluctuations in the cervical vessel dimension of the patient; identifying a patient physiological cycle; and providing a neural modulation therapy in coordination with the identified patient physiological cycle, wherein a parameter of the neural modulation therapy is determined in part using a first characteristic of the pulsatile signal. - View Dependent Claims (17, 18, 19)
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20. A medical device for controlling at least a portion of a neural modulation therapy, the device comprising:
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a detector circuit configured to detect cervical impedance of a patient and generate a cervical impedance signal representing fluctuations in the detected cervical impedance over time; a therapy delivery circuit configured to provide neural modulation therapy to the patient using a neural modulation therapy timing parameter, the timing parameter corresponding to a specified portion of a physiologic cycle of the patient; and a processor circuit, coupled to the detector circuit and the therapy delivery circuit, the processor circuit configured to; determine a pulsatile signal using the cervical impedance signal; identify at least one characteristic of the pulsatile signal; and control delivery of the neural modulation therapy using the neural modulation therapy timing parameter and the at least one identified characteristic of the pulsatile signal.
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Specification