Optical capsule and spectroscopic method for treating and diagnosing the intestinal tract
First Claim
1. A diagnostic system comprising:
- an autonomous capsule sized to pass through an intestinal tract of a patient, the capsule comprising;
a light source configured to emit light from the capsule so that the emitted light is reflected from intestinal tract tissue when the capsule is moving through the intestinal tract; and
a sensor configured to sense reflected light for at least one predetermined wavelength at a first location within the intestinal tract and to output a signal representative of light sensed by the sensor at the at least one predetermined wavelength, each at least one predetermined wavelength associated with a corresponding condition of intestinal tract tissue;
a processor coupled to the sensor and configured to receive a signal representative of light sensed by the sensor, the processor further configured to associate each of the at least one predetermined wavelength with the corresponding condition of intestinal tract tissue, to select a gastrointestinal condition of intestinal tract tissue for detection, to control the emission of light from the light source for detecting the selected condition, to control wavelengths of light sensed by the sensor, and to determine the presence of the condition of intestinal tract tissue based at least in part on the received signal, the condition being at least one of a presence of a substance, an absence of a substance, or a condition of tissue of the intestinal tract;
a capsule tracking system configured to track a location of the capsule within the intestinal tract independent of capsule orientation, via calculating a transmission time of an acoustic tracking signal transmitted from one of (a) the autonomous capsule or (b) a location external a patient'"'"'s body, to the other of the autonomous capsule or the location external to the patient'"'"'s body, anda battery disposed within the capsule for powering the light source, the sensor, and portions of the capsule tracking system as the capsule is moving through the intestinal tract, the battery configured to allow the capsule to emit and sense light along a length of the intestinal tract when the acoustic tracking signal is transmitted without receiving external power, so as to develop a map of sensed optical characteristics along the length of the intestinal tract.
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Accused Products
Abstract
A device and method for mapping, diagnosing and treating disorders or other diseases, disorders or conditions (e.g., bleeding, ischemic or necrotic tissue, and presence of certain chemicals or substances) of the intestinal tract is provided using a capsule passing through the intestinal tract and sensing optical characteristics as the capsule passes through. Further, a capsule tracking system is provided for tracking a capsule'"'"'s location along the length of an intestinal tract as various treatment and/or sensing modalities are employed. In one variation, an acoustic signal is used to determine the location of the capsule. A map of optical characteristics may be derived from the pass of a capsule to diagnose the disorder or disease. The capsule or subsequently passed capsules may treat, further diagnose or mark the intestinal tract at a determined location along its length.
100 Citations
29 Claims
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1. A diagnostic system comprising:
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an autonomous capsule sized to pass through an intestinal tract of a patient, the capsule comprising;
a light source configured to emit light from the capsule so that the emitted light is reflected from intestinal tract tissue when the capsule is moving through the intestinal tract; and
a sensor configured to sense reflected light for at least one predetermined wavelength at a first location within the intestinal tract and to output a signal representative of light sensed by the sensor at the at least one predetermined wavelength, each at least one predetermined wavelength associated with a corresponding condition of intestinal tract tissue;a processor coupled to the sensor and configured to receive a signal representative of light sensed by the sensor, the processor further configured to associate each of the at least one predetermined wavelength with the corresponding condition of intestinal tract tissue, to select a gastrointestinal condition of intestinal tract tissue for detection, to control the emission of light from the light source for detecting the selected condition, to control wavelengths of light sensed by the sensor, and to determine the presence of the condition of intestinal tract tissue based at least in part on the received signal, the condition being at least one of a presence of a substance, an absence of a substance, or a condition of tissue of the intestinal tract; a capsule tracking system configured to track a location of the capsule within the intestinal tract independent of capsule orientation, via calculating a transmission time of an acoustic tracking signal transmitted from one of (a) the autonomous capsule or (b) a location external a patient'"'"'s body, to the other of the autonomous capsule or the location external to the patient'"'"'s body, and a battery disposed within the capsule for powering the light source, the sensor, and portions of the capsule tracking system as the capsule is moving through the intestinal tract, the battery configured to allow the capsule to emit and sense light along a length of the intestinal tract when the acoustic tracking signal is transmitted without receiving external power, so as to develop a map of sensed optical characteristics along the length of the intestinal tract. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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28. A diagnostic system comprising:
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an autonomous capsule sized to pass through an intestinal tract of a patient, the capsule comprising;
a light source configured to emit light from the capsule so that the emitted light is reflected from intestinal tract tissue when the capsule is moving through the intestinal tract; and
a sensor configured to sense light for at least one predetermined wavelength and to output a signal representative of light sensed by the sensor at the at least one predetermined wavelength, each at least one predetermined wavelength associated with a presence of blood within the intestinal tract at a first location;a processor coupled to the sensor and configured to receive a signal representative of light sensed by the sensor, the processor further configured to select the presence of blood as a condition to be detected, associate each of the at least one predetermined wavelength with the presence of blood within the intestinal tract, to control the emission of light from the light source for detecting presence of blood in the intestinal tract, to control wavelengths of light sensed by the sensor, and to detect bleeding in the gastrointestinal tract by determining the presence of blood at the first location within the intestinal tract based at least in part on the received signal; a capsule tracking system configured to track a location of the capsule within the intestinal tract independent of capsule orientation, via calculating a transmission time of an acoustic tracking signal transmitted from one of (a) the autonomous capsule or (b) a location external a patient'"'"'s body, to the other of the autonomous capsule or the location external to the patient'"'"'s body; and a battery disposed within the capsule for powering the light source, the sensor, and portions of the capsule tracking system as the capsule is moving through the intestinal tract, the battery configured to allow the capsule to emit and sense light along a length of the intestinal tract when the acoustic tracking signal is transmitted without receiving external power so as to develop a map of a sensed optical characteristics along the length of the intestinal tract. - View Dependent Claims (29)
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Specification