Implants and methods for spinal fusion

• US 9,168,152 B2
• Filed: 12/27/2011
• Issued: 10/27/2015
• Est. Priority Date: 02/29/2008
• Status: Active Grant

• Current Assignee: Nuvasive Incorporated
• Original Assignee: Nuvasive Incorporated
• Inventors: Raiszadeh, Kamshad, VerHage, Benjamin, Mindoro, Michael, Arambula, Jared, Ahlgren, Dan K., Di Lauro, Michael C.
• Primary Examiner(s): HOFFMAN, MARY C
• Application Number:
  US13/337,967
• Publication Number:
  US 20120101582A1
• Time in Patent Office: 1,400 Days
• Field of Search: 623 1711- 1716
• US Class Current: 1/1
• CPC Class Codes: A61F 2/442 Intervertebral or spinal discs, e.g. resilient non-disc-shaped intervertebral inflatable pockets A61F2/441; non-disc-shaped intervertebral fusion implants A61F2/4455
• CPC Class Codes: A61F 2/447 substantially parallelepipedal, e.g. having a rectangular or trapezoidal cross-section
• CPC Class Codes: A61F 2/4603 for insertion or extraction of endoprosthetic joints or of accessories thereof
• CPC Class Codes: A61F 2/4611 of spinal prostheses
• CPC Class Codes: A61F 2/4684 Trial or dummy prostheses
• CPC Class Codes: A61F 2002/2817 Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
• CPC Class Codes: A61F 2002/2835 Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
• CPC Class Codes: A61F 2002/3008 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2002/30477 using sharp protrusions, e.g. spikes, for anchoring into connecting prosthetic part
• CPC Class Codes: A61F 2002/30578 having apertures, e.g. for receiving fixation screws
• CPC Class Codes: A61F 2002/30593 hollow
• CPC Class Codes: A61F 2002/30604 modular
• CPC Class Codes: A61F 2002/30774 internally-threaded
• CPC Class Codes: A61F 2002/30785 parallel
• CPC Class Codes: A61F 2002/3082 Grooves
• CPC Class Codes: A61F 2002/30841 Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
• CPC Class Codes: A61F 2002/30878 with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
• CPC Class Codes: A61F 2002/30904 serrated profile, i.e. saw-toothed
• CPC Class Codes: A61F 2002/4629 connected to the endoprosthesis or implant via a threaded connection
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2230/0019 : rectangular
• CPC Class Codes: A61F 2310/00023 : Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00976 : Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF

Abstract

An implant is provided for performing spinal fusion. The implant includes an implant body having a leading side and a trailing side at opposing ends along a longitudinal axis. Between the leading side and trailing side are an upper surface, a lower surface, an anterior side, and a posterior side. At least one keel structure is provided extending from the implant body for penetration into an adjacent vertebral body. A trial sizer and keel cutter may be utilized to form keel channels within the vertebral body to receive the keel structure.

Claims

1. A spinal fusion implant positionable within an interbody space between a first vertebral endplate and a second vertebral endplate, said interbody space being at least partially defined by a posterior aspect, and anterior aspect, and opposing lateral aspects, said implant comprising:

an implant body having a top surface configured to engage said first vertebral endplate when said implant is positioned within the interbody space, a bottom surface configured to engage said second vertebral endplate when said implant is positioned within the interbody space, a distal side, a proximal side, a first side wall defining an anterior side when said implant is positioned within the interbody space, and a second side wall defining a posterior side when said implant is positioned within the interbody space, said implant having a length extending from said proximal side to said distal side, a width extending from said first side wall to said second side wall, and a height extending from said top surface to said bottom surface, said length being dimensioned so as to extend between said lateral aspects of said interbody space when said implant is positioned within the interbody space and is at least two and a half times greater than said width, said width being greater than said height, said implant further including at least one fusion aperture extending between the top and bottom surfaces and permit bone growth between the first vertebral endplate and the second vertebral endplate when said implant is positioned within the interbody space, said top surface and said bottom surface of said implant body each including a keel channel extending along at least a portion of the length of the implant body; and

a first keel structure configured to be received within the keel channel in the top surface of the implant body such that a portion of the keel structure extends above the top surface of the implant body and a second keel structure configured to be received within the keel channel in the bottom surface of the implant body such that a portion of the keel structure extends below the bottom surface of the implant.

2. The spinal fusion implant of claim 1, wherein the at least one keel structure is positioned along the centerline of the implant.

3. The spinal fusion implant of claim 1, wherein the fusion aperture is generally rectangular in shape.

4. The spinal fusion implant of claim 1, wherein at least one visualization aperture extends through at least one of the anterior side and the posterior side of the implant.

5. The spinal fusion implant of claim 1, wherein the anterior side has a greater height dimension than the posterior side.

6. The spinal fusion implant of claim 1, further including osteoinductive materials positioned in thefusion aperture and including at least one of autologous bone harvested from the patient, bone allograft, bone xenograft, bone morphogenic protein, or bio-resorbable compositions.

7. The spinal fusion implant of claim 1, including anti-migration features comprising at least one of angled ridges formed along the upper surface, angled ridges formed along the lower surface, and one or more spike members disposed at various locations along the implant.